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The map label for this gene is AraC [H]

Identifier: 20808709

GI number: 20808709

Start: 2228069

End: 2229628

Strand: Reverse

Name: AraC [H]

Synonym: TTE2343

Alternate gene names: 20808709

Gene position: 2229628-2228069 (Counterclockwise)

Preceding gene: 20808710

Following gene: 20808708

Centisome position: 82.9

GC content: 34.62

Gene sequence:

>1560_bases
ATGAAGCTATTTATAGCCGATGATGAAGTGGAGGTTGTGGAGGGAATTTTGACACTTATTGATTGGAAAGGGAATGGGAT
TGAACTTGTAGGATATGCCATGGATGGAGAAGAAGCTCTTTATAAGATAAAAAGTTTAAAGCCCGATATTGTGCTAATAG
ACATACGGATGCCTAAATTAGATGGGCTTGAAGTGATTGAGAAGGCGCAAGGAGAGGGAATAAGGTTTAAAAGTATAATT
TTGAGCGGATATGATGACTTTTACTTTGCCAAGAAAGCTATAGAGCTTAAAAGCTTTAGCTACCTTTTAAAGCCATGTAG
ACCTGAAGAAATTTTAAAAGAGGTTTTAAAAGCCAGGGAAGATATTGAAAAAGAGATAGAAAAGGAAAATACTTTAAAGG
AGTTTATCAATTACTACAATGATACTCTTCCGGTGATTAGAGAAAGGGTACTAAGTGAAGTGCTATATAGAGTGAGGTCT
TCTTCTGAAGTGGCAGAAGATTTCGTGAAATATAAAATAGATTTTCCTTATAAAAAGTACTGCGTGGTTTTGATGAAAAT
TGAAATAGAAGCTCAAAATGAAATAGAAGAAGCCTATAAGCTCGCTTGTGCTGATGTAATAAGGAAAAAGGCTGGGGATA
TGAAGATTGAGGTAATAAGGGATAGAGAAGAAATTGCAATTTTGATAAATTCTGAAGAGGAATTTAAAAAAGAGAGTATT
GAAGGGTTTTTAAATGATGTGAAAAGCGAGATATATGATAAGCTTGAAGTTCGTGCATATTTTGGGATTGGCAAGTGGGT
AGAAGGAGCGGACAAGATAAAATATTCTTATTATCAGGCAAAGGAGGCGCTGGAGCTTAAGTTTTTTGCAGAGGAATTTG
ATGCGATTTTTTATGAAGATATATGGCCTCATCAGGATAACCTTTACTATCCTGTAAATGAAGAGAGGGAAATAATAAAC
AGTGTGATTTTAAACAAAAGGGAGGATTTGAATAAAAAAGTGGAGAATTTTTTAAATGCCCTTTATACGGGTGGTTTTAA
CCAGTGGTTTGTCAAGGCTTCTATTTTGGTTTTGCTGGGAAATTTGATAAAAGCTTGCTATGAGAAGAATGTGGATATTG
GAGATATTGCAGGAGAAAAGGCCTTTGAGGGCATTTTAAAAGCCGACAGAAAAGAGACATTAAAGTCCCTCTCTTTAAGC
GTAATTTACAAAATTGCCGAAAAAATAGAAAGAGCGGGAGATAAGAACCCCATAATAAAAGACGCCGTAGAGTATATAGA
CAAAAATTATGATAAAGATATAAGTTTGGAAAGTGTTGCAAAAGAAGTATATGTAACTCCTGCATATCTTAGCATTCTGT
TTAAAAAAGAGATGAATATAAATTTTGTGAGTTATTTACACAAAGTTAGAGTGGAAAAGGCTAAGAAGCTTCTTGAAGAT
AGGAGTTTAAAGACATATCAAGTAGCAAATATGGTGGGGTTTGGAGATGAGAAATATTTTTCACAGGTATTTAAAAAGTA
CACAGGGCTTACTCCTTCTCAGTATAGAGACAGCCTTTAG

Upstream 100 bases:

>100_bases
TTATGGAGATAAGTATGAGCTTAAAATAGAGAGTAGGCAAGGAGAAGGGACAACCATTTCCCTTATATTGCCTGAAAGTA
TATCTTAAGGGGGAGGGCGT

Downstream 100 bases:

>100_bases
GAGTTTTTATTTTTTTGTGCTATAATATTTTTGAAAACATTTTATTAGGGGGCGTTTTTAATGGAGAAGTTACAATTAGA
AGATTTTACAAAATTTAAAT

Product: AraC-type DNA-binding domain-containing proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MKLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEALYKIKSLKPDIVLIDIRMPKLDGLEVIEKAQGEGIRFKSII
LSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKAREDIEKEIEKENTLKEFINYYNDTLPVIRERVLSEVLYRVRS
SSEVAEDFVKYKIDFPYKKYCVVLMKIEIEAQNEIEEAYKLACADVIRKKAGDMKIEVIRDREEIAILINSEEEFKKESI
EGFLNDVKSEIYDKLEVRAYFGIGKWVEGADKIKYSYYQAKEALELKFFAEEFDAIFYEDIWPHQDNLYYPVNEEREIIN
SVILNKREDLNKKVENFLNALYTGGFNQWFVKASILVLLGNLIKACYEKNVDIGDIAGEKAFEGILKADRKETLKSLSLS
VIYKIAEKIERAGDKNPIIKDAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFVSYLHKVRVEKAKKLLED
RSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYRDSL

Sequences:

>Translated_519_residues
MKLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEALYKIKSLKPDIVLIDIRMPKLDGLEVIEKAQGEGIRFKSII
LSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKAREDIEKEIEKENTLKEFINYYNDTLPVIRERVLSEVLYRVRS
SSEVAEDFVKYKIDFPYKKYCVVLMKIEIEAQNEIEEAYKLACADVIRKKAGDMKIEVIRDREEIAILINSEEEFKKESI
EGFLNDVKSEIYDKLEVRAYFGIGKWVEGADKIKYSYYQAKEALELKFFAEEFDAIFYEDIWPHQDNLYYPVNEEREIIN
SVILNKREDLNKKVENFLNALYTGGFNQWFVKASILVLLGNLIKACYEKNVDIGDIAGEKAFEGILKADRKETLKSLSLS
VIYKIAEKIERAGDKNPIIKDAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFVSYLHKVRVEKAKKLLED
RSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYRDSL
>Mature_519_residues
MKLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEALYKIKSLKPDIVLIDIRMPKLDGLEVIEKAQGEGIRFKSII
LSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKAREDIEKEIEKENTLKEFINYYNDTLPVIRERVLSEVLYRVRS
SSEVAEDFVKYKIDFPYKKYCVVLMKIEIEAQNEIEEAYKLACADVIRKKAGDMKIEVIRDREEIAILINSEEEFKKESI
EGFLNDVKSEIYDKLEVRAYFGIGKWVEGADKIKYSYYQAKEALELKFFAEEFDAIFYEDIWPHQDNLYYPVNEEREIIN
SVILNKREDLNKKVENFLNALYTGGFNQWFVKASILVLLGNLIKACYEKNVDIGDIAGEKAFEGILKADRKETLKSLSLS
VIYKIAEKIERAGDKNPIIKDAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFVSYLHKVRVEKAKKLLED
RSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYRDSL

Specific function: Member of the two-component regulatory system yesM/yesN [H]

COG id: COG4753

COG function: function code T; Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=112, Percent_Identity=39.2857142857143, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786251, Length=124, Percent_Identity=35.4838709677419, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788725, Length=147, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787987, Length=102, Percent_Identity=30.3921568627451, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00165 HTH_AraC; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 60318; Mature: 60318

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEALYKIKSLKPDIVLIDIRMPKL
CEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHCCCCCEEEEEEECCCC
DGLEVIEKAQGEGIRFKSIILSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKARE
CCHHHHHHCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DIEKEIEKENTLKEFINYYNDTLPVIRERVLSEVLYRVRSSSEVAEDFVKYKIDFPYKKY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCHHHH
CVVLMKIEIEAQNEIEEAYKLACADVIRKKAGDMKIEVIRDREEIAILINSEEEFKKESI
EEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCHHHHHHHHH
EGFLNDVKSEIYDKLEVRAYFGIGKWVEGADKIKYSYYQAKEALELKFFAEEFDAIFYED
HHHHHHHHHHHHHHHHHHHEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWPHQDNLYYPVNEEREIINSVILNKREDLNKKVENFLNALYTGGFNQWFVKASILVLLG
CCCCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NLIKACYEKNVDIGDIAGEKAFEGILKADRKETLKSLSLSVIYKIAEKIERAGDKNPIIK
HHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
DAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFVSYLHKVRVEKAKKLLED
HHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYRDSL
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MKLFIADDEVEVVEGILTLIDWKGNGIELVGYAMDGEEALYKIKSLKPDIVLIDIRMPKL
CEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHCCCCCEEEEEEECCCC
DGLEVIEKAQGEGIRFKSIILSGYDDFYFAKKAIELKSFSYLLKPCRPEEILKEVLKARE
CCHHHHHHCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DIEKEIEKENTLKEFINYYNDTLPVIRERVLSEVLYRVRSSSEVAEDFVKYKIDFPYKKY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCHHHH
CVVLMKIEIEAQNEIEEAYKLACADVIRKKAGDMKIEVIRDREEIAILINSEEEFKKESI
EEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCHHHHHHHHH
EGFLNDVKSEIYDKLEVRAYFGIGKWVEGADKIKYSYYQAKEALELKFFAEEFDAIFYED
HHHHHHHHHHHHHHHHHHHEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWPHQDNLYYPVNEEREIINSVILNKREDLNKKVENFLNALYTGGFNQWFVKASILVLLG
CCCCCCCEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
NLIKACYEKNVDIGDIAGEKAFEGILKADRKETLKSLSLSVIYKIAEKIERAGDKNPIIK
HHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
DAVEYIDKNYDKDISLESVAKEVYVTPAYLSILFKKEMNINFVSYLHKVRVEKAKKLLED
HHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSLKTYQVANMVGFGDEKYFSQVFKKYTGLTPSQYRDSL
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]