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The map label for this gene is Dap2.2 [H]

Identifier: 20808708

GI number: 20808708

Start: 2226011

End: 2228008

Strand: Reverse

Name: Dap2.2 [H]

Synonym: TTE2342

Alternate gene names: 20808708

Gene position: 2228008-2226011 (Counterclockwise)

Preceding gene: 20808709

Following gene: 20808706

Centisome position: 82.84

GC content: 36.84

Gene sequence:

>1998_bases
ATGGAGAAGTTACAATTAGAAGATTTTACAAAATTTAAATTTTTGTCAGGATTAAAATATTCACCAAGTGGTAGCTGTGC
AGCATTTGTGGTACATAGAATGGATGTTGAGGAGAACAAGTATTTGTCTAACATATGGGTTTTGGATACAAAGACTAAAA
AATATTTTCAGCTGACTTCCTTTAATGAGGAGAGAGGATTTGTATGGCTTGACGATGATTACATACTTTTTGCAGGTAGC
AGAAATCCAAAGGACAAAGAAAAGGCAGAAAGTGGAGAGGAATTTACAAAGTACTACAAGATTAATATACACGGAGGAGA
AGCTGTTGAGGCTTTTGTGATACCTAAAAAGGTTACAGAGATTTTGCCTGTTGATGACGATACTTTTCTCTTGATTGCAC
TTTATAATGTGAATAAAAAGGATTTGGAGGGTTTGAGTGAGGAGGAGAAGAAAAAAGAGCTTGAAAGGAGAAAAGAGGAG
AAAGATTACGAAGTATTTGATGAGATTCCTTTTTGGGCGAATGGCGAAGGAGTCATCAATAAAGACAGGGGAAGGCTCTA
TGTTTATAAATTAAGTGATAATAAATTGCAGCCTATAACAGATGAATACACTGATGTGTATTCTTTAAAGCTCAACAAAG
ATAAGACAAAAGCTGTGTTTATAGGAAAAAGTTATAAGGGCAAAATGCCTTTGACAAGTGATGTTTATATATACAATTTA
AAGGTTGGAGAACTTAAGAAAGTGAATAAGGATTCAGATTTTTCCTATAGGTATGTGGATTTTTTAGGAGATAAGATAAT
ATGCGCTGGAACAGATATGAAAAAATACGGTATAAATGAAAACAGCAAGTTCTACATTTTAGAGGAGTCAGGCGAAAGAA
GGTGCATAACCCCTGAGCTCGATATGAGTTTAGGAAATTCTGTAAACTCTGATGTGAGGTACGGTTCAGGCTTTAGTTTT
AAAGCAGAAGGAGATTATTTGTACTTCATATCTACAGAGAGGTACAATGCTTATCTTAACAGGATAAATTTAGAAGGGAA
AATAGAAAAAGTGATAGATAAAGATGGATCTGTGGATATGTTTGATGTATGTGGCGATAATATTCTTTTTATCGGTTTTA
GAGGATTAAAGCTTTTGGAGCTTTATGAGTACAAAGATGGGCAGGAGATACAGATTACTGACTTTAATGAGTGGGTGCAG
AAAGAAAAGAAACTTTCAAAGCCTGAAAGAGTAGAGGTAGAGACGAGGCCAGGGCATTTTATAGATGGTTGGGTTATAAA
GCCTGTAGACTATGAAGAAGGGAAGAAGTATCCTGCAATATTAGATATACATGGTGGTCCTAAAACAGTATATGGTGAAG
TATACTTCCATGAAATGCAGTACTGGGCTTCAGAAGGGTATTTTGTGTTTTTCTGCAATCCGGTAGGAAGCGATGGCAGA
GGAAACGAATTTGCTGATATAAGAGGAAAATATGGGACAATTGACTATGAAGATATAATGAAATTTACAGATTATGTGCT
TGAAAATTACAAAGACATTGACCCCGAAAGAGTTGGGGTTACAGGTGGATCTTACGGTGGATTTATGACAAACTGGATAA
TAGGGCATACAGATAGGTTTAAGGCAGCAGTATCTCAAAGGAGCATATCAAACTGGTTTACAGAGTTTGGAACTACAGAT
ATAGGTTATTACTTTGTGCCAGATCAGGTGGGCGGTACTCCCTGGGACAACTTTGAGAAATACTGGGACAATTCTCCGCT
TAAATATGCTGATAAAGTGAAGACTCCGACATTGTTCCTGCATTCTGATGAGGATTTTAGGTGCTGGCTTGCTGAAGCTC
TTCAAATGTTCACGGCCCTTAAGTACTTTGGTGTAGAGTCAAGGTTGGTGATCTGTCATGGTGAAAACCACGACCTTTCA
AGGAGCGGAAAACCAAAGCACAGGATAAGAAGGCTTAAAGAGATAACTGATTGGTTTAATAAGTACCTTAAAGGATGA

Upstream 100 bases:

>100_bases
CACAGGGCTTACTCCTTCTCAGTATAGAGACAGCCTTTAGGAGTTTTTATTTTTTTGTGCTATAATATTTTTGAAAACAT
TTTATTAGGGGGCGTTTTTA

Downstream 100 bases:

>100_bases
ATAAAAGAGGCATCTTGAGTGGTTCAAGATGCCTCTTTTTATGCAAGTAGTGCGGCCACTACTCCGACTAAAAATATTCC
ATCAAATATTCCCGCACCAC

Product: dipeptidyl aminopeptidase/acylaminoacyl-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MEKLQLEDFTKFKFLSGLKYSPSGSCAAFVVHRMDVEENKYLSNIWVLDTKTKKYFQLTSFNEERGFVWLDDDYILFAGS
RNPKDKEKAESGEEFTKYYKINIHGGEAVEAFVIPKKVTEILPVDDDTFLLIALYNVNKKDLEGLSEEEKKKELERRKEE
KDYEVFDEIPFWANGEGVINKDRGRLYVYKLSDNKLQPITDEYTDVYSLKLNKDKTKAVFIGKSYKGKMPLTSDVYIYNL
KVGELKKVNKDSDFSYRYVDFLGDKIICAGTDMKKYGINENSKFYILEESGERRCITPELDMSLGNSVNSDVRYGSGFSF
KAEGDYLYFISTERYNAYLNRINLEGKIEKVIDKDGSVDMFDVCGDNILFIGFRGLKLLELYEYKDGQEIQITDFNEWVQ
KEKKLSKPERVEVETRPGHFIDGWVIKPVDYEEGKKYPAILDIHGGPKTVYGEVYFHEMQYWASEGYFVFFCNPVGSDGR
GNEFADIRGKYGTIDYEDIMKFTDYVLENYKDIDPERVGVTGGSYGGFMTNWIIGHTDRFKAAVSQRSISNWFTEFGTTD
IGYYFVPDQVGGTPWDNFEKYWDNSPLKYADKVKTPTLFLHSDEDFRCWLAEALQMFTALKYFGVESRLVICHGENHDLS
RSGKPKHRIRRLKEITDWFNKYLKG

Sequences:

>Translated_665_residues
MEKLQLEDFTKFKFLSGLKYSPSGSCAAFVVHRMDVEENKYLSNIWVLDTKTKKYFQLTSFNEERGFVWLDDDYILFAGS
RNPKDKEKAESGEEFTKYYKINIHGGEAVEAFVIPKKVTEILPVDDDTFLLIALYNVNKKDLEGLSEEEKKKELERRKEE
KDYEVFDEIPFWANGEGVINKDRGRLYVYKLSDNKLQPITDEYTDVYSLKLNKDKTKAVFIGKSYKGKMPLTSDVYIYNL
KVGELKKVNKDSDFSYRYVDFLGDKIICAGTDMKKYGINENSKFYILEESGERRCITPELDMSLGNSVNSDVRYGSGFSF
KAEGDYLYFISTERYNAYLNRINLEGKIEKVIDKDGSVDMFDVCGDNILFIGFRGLKLLELYEYKDGQEIQITDFNEWVQ
KEKKLSKPERVEVETRPGHFIDGWVIKPVDYEEGKKYPAILDIHGGPKTVYGEVYFHEMQYWASEGYFVFFCNPVGSDGR
GNEFADIRGKYGTIDYEDIMKFTDYVLENYKDIDPERVGVTGGSYGGFMTNWIIGHTDRFKAAVSQRSISNWFTEFGTTD
IGYYFVPDQVGGTPWDNFEKYWDNSPLKYADKVKTPTLFLHSDEDFRCWLAEALQMFTALKYFGVESRLVICHGENHDLS
RSGKPKHRIRRLKEITDWFNKYLKG
>Mature_665_residues
MEKLQLEDFTKFKFLSGLKYSPSGSCAAFVVHRMDVEENKYLSNIWVLDTKTKKYFQLTSFNEERGFVWLDDDYILFAGS
RNPKDKEKAESGEEFTKYYKINIHGGEAVEAFVIPKKVTEILPVDDDTFLLIALYNVNKKDLEGLSEEEKKKELERRKEE
KDYEVFDEIPFWANGEGVINKDRGRLYVYKLSDNKLQPITDEYTDVYSLKLNKDKTKAVFIGKSYKGKMPLTSDVYIYNL
KVGELKKVNKDSDFSYRYVDFLGDKIICAGTDMKKYGINENSKFYILEESGERRCITPELDMSLGNSVNSDVRYGSGFSF
KAEGDYLYFISTERYNAYLNRINLEGKIEKVIDKDGSVDMFDVCGDNILFIGFRGLKLLELYEYKDGQEIQITDFNEWVQ
KEKKLSKPERVEVETRPGHFIDGWVIKPVDYEEGKKYPAILDIHGGPKTVYGEVYFHEMQYWASEGYFVFFCNPVGSDGR
GNEFADIRGKYGTIDYEDIMKFTDYVLENYKDIDPERVGVTGGSYGGFMTNWIIGHTDRFKAAVSQRSISNWFTEFGTTD
IGYYFVPDQVGGTPWDNFEKYWDNSPLKYADKVKTPTLFLHSDEDFRCWLAEALQMFTALKYFGVESRLVICHGENHDLS
RSGKPKHRIRRLKEITDWFNKYLKG

Specific function: Unknown

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=248, Percent_Identity=25.8064516129032, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI18450280, Length=244, Percent_Identity=29.0983606557377, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI37577089, Length=244, Percent_Identity=29.0983606557377, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI194394146, Length=163, Percent_Identity=31.2883435582822, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552908, Length=250, Percent_Identity=28.8, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25149159, Length=234, Percent_Identity=29.4871794871795, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508017, Length=159, Percent_Identity=30.188679245283, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508019, Length=159, Percent_Identity=30.188679245283, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551969, Length=275, Percent_Identity=25.4545454545455, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45550825, Length=275, Percent_Identity=25.4545454545455, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45553511, Length=275, Percent_Identity=25.4545454545455, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582257, Length=264, Percent_Identity=24.6212121212121, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 77359; Mature: 77359

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLQLEDFTKFKFLSGLKYSPSGSCAAFVVHRMDVEENKYLSNIWVLDTKTKKYFQLTS
CCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEC
FNEERGFVWLDDDYILFAGSRNPKDKEKAESGEEFTKYYKINIHGGEAVEAFVIPKKVTE
CCCCCCEEEECCCEEEEECCCCCCHHHHHHCCCCEEEEEEEEECCCCEEEEEEECHHHHH
ILPVDDDTFLLIALYNVNKKDLEGLSEEEKKKELERRKEEKDYEVFDEIPFWANGEGVIN
HCCCCCCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEE
KDRGRLYVYKLSDNKLQPITDEYTDVYSLKLNKDKTKAVFIGKSYKGKMPLTSDVYIYNL
CCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEE
KVGELKKVNKDSDFSYRYVDFLGDKIICAGTDMKKYGINENSKFYILEESGERRCITPEL
ECCCHHCCCCCCCCCEEEHHHCCCEEEEECCCHHHCCCCCCCEEEEEECCCCCEEECCCC
DMSLGNSVNSDVRYGSGFSFKAEGDYLYFISTERYNAYLNRINLEGKIEKVIDKDGSVDM
CHHCCCCCCCCCCCCCCEEEEECCCEEEEEECCHHEEEHEEECCCCHHHHHHCCCCCEEE
FDVCGDNILFIGFRGLKLLELYEYKDGQEIQITDFNEWVQKEKKLSKPERVEVETRPGHF
HCCCCCCEEEEEECCEEEEEEEECCCCCEEEEECHHHHHHHHHHCCCCCEEEEECCCCCE
IDGWVIKPVDYEEGKKYPAILDIHGGPKTVYGEVYFHEMQYWASEGYFVFFCNPVGSDGR
ECCEEEECCCHHCCCCCCEEEEECCCCCEEEEEEEEEEHHHHHCCCEEEEEECCCCCCCC
GNEFADIRGKYGTIDYEDIMKFTDYVLENYKDIDPERVGVTGGSYGGFMTNWIIGHTDRF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCCHHHHEEECCCHHH
KAAVSQRSISNWFTEFGTTDIGYYFVPDQVGGTPWDNFEKYWDNSPLKYADKVKTPTLFL
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCHHHCCCCCEEEE
HSDEDFRCWLAEALQMFTALKYFGVESRLVICHGENHDLSRSGKPKHRIRRLKEITDWFN
ECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
KYLKG
HHHCC
>Mature Secondary Structure
MEKLQLEDFTKFKFLSGLKYSPSGSCAAFVVHRMDVEENKYLSNIWVLDTKTKKYFQLTS
CCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEC
FNEERGFVWLDDDYILFAGSRNPKDKEKAESGEEFTKYYKINIHGGEAVEAFVIPKKVTE
CCCCCCEEEECCCEEEEECCCCCCHHHHHHCCCCEEEEEEEEECCCCEEEEEEECHHHHH
ILPVDDDTFLLIALYNVNKKDLEGLSEEEKKKELERRKEEKDYEVFDEIPFWANGEGVIN
HCCCCCCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEE
KDRGRLYVYKLSDNKLQPITDEYTDVYSLKLNKDKTKAVFIGKSYKGKMPLTSDVYIYNL
CCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEE
KVGELKKVNKDSDFSYRYVDFLGDKIICAGTDMKKYGINENSKFYILEESGERRCITPEL
ECCCHHCCCCCCCCCEEEHHHCCCEEEEECCCHHHCCCCCCCEEEEEECCCCCEEECCCC
DMSLGNSVNSDVRYGSGFSFKAEGDYLYFISTERYNAYLNRINLEGKIEKVIDKDGSVDM
CHHCCCCCCCCCCCCCCEEEEECCCEEEEEECCHHEEEHEEECCCCHHHHHHCCCCCEEE
FDVCGDNILFIGFRGLKLLELYEYKDGQEIQITDFNEWVQKEKKLSKPERVEVETRPGHF
HCCCCCCEEEEEECCEEEEEEEECCCCCEEEEECHHHHHHHHHHCCCCCEEEEECCCCCE
IDGWVIKPVDYEEGKKYPAILDIHGGPKTVYGEVYFHEMQYWASEGYFVFFCNPVGSDGR
ECCEEEECCCHHCCCCCCEEEEECCCCCEEEEEEEEEEHHHHHCCCEEEEEECCCCCCCC
GNEFADIRGKYGTIDYEDIMKFTDYVLENYKDIDPERVGVTGGSYGGFMTNWIIGHTDRF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCCHHHHEEECCCHHH
KAAVSQRSISNWFTEFGTTDIGYYFVPDQVGGTPWDNFEKYWDNSPLKYADKVKTPTLFL
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCHHHCCCCCEEEE
HSDEDFRCWLAEALQMFTALKYFGVESRLVICHGENHDLSRSGKPKHRIRRLKEITDWFN
ECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
KYLKG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]