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The map label for this gene is 20808694

Identifier: 20808694

GI number: 20808694

Start: 2211107

End: 2212120

Strand: Reverse

Name: 20808694

Synonym: TTE2328

Alternate gene names: NA

Gene position: 2212120-2211107 (Counterclockwise)

Preceding gene: 20808695

Following gene: 20808693

Centisome position: 82.25

GC content: 39.25

Gene sequence:

>1014_bases
ATGCTACAATATGATAAAGACGTAGTGTTATCCAGTCGAATTAGGTTGGCTCGCAATGTAAAAGACATTCCTTTTCCAAC
TGTCATGACTGAAGAACAAGGCAAAAAAGTCATTGAGCTCGCCAGGAAGGCAATTCTAGGCAGCAATACTATCCTATCCA
CCCAATTTACGGAGTATGAGATGAAAAAGTTGACCCCTTTAGACAGGCAGGCATTGGTTGAAAAACACCTTATAAGCCCT
GACCTTTCTCAAAATATAAAAACCGGATATGCTCTTATAAAAGACGATAATACTGTGAGCATCATGGTAAATGAAGAAGA
CCATTTGAGGATACAATGCATTCTGCCGGGTTTGAAGCTTGATGAGAGCTGGGATATGGCTGACAAAATTGATGATTTAA
TTGAAGAGACGATTGACTATGCTTACGACGAAAAGATAGGATACTTAACTTCATGCCCTACAAATGTCGGCACAGGGATA
AGAGCTTCAGTTATGGTACATCTTCCAGCTTTAACAATAACCGGGCAGATAAGCAATATTCTAAATTCTGTTTCTAAAAT
AGGGATGGCAGTAAGGGGTATATACGGAGAAGGCACTCAAGCTTTAGGAGATATATACCAGATTTCCAATCAGGTAACTT
TGGGGCAGAGTGAAAAAGAGATAATAGAAAATATCGAAGGAGTTGCTAAACAGATAATTTCAAGCGAAAGAAGAGCAAGG
GAGGAACTTTACAAAAAACAAAGAGTTCAGATAGAGGACAGAGTAGGAAGAGCATTTGGTATCTTGTCTCATGCCAAAGT
GATGTCCACCAAAGAGTACATGACTTTGATGTCTGACGTAAGGCTTGGGATTGTTTTGGGAATATTAAGTGTGGACCTTG
ATAAACTCGACAGACTCACCACTCAAATACAGCCTGCTAATCTCCAGAAGATTTACGGCATGCAACTTAACCCTTATGAG
AGGGATGTGAAAAGAGCTGAATATGTGTCCACTCAGTTAAATAAAAAAGAATAA

Upstream 100 bases:

>100_bases
AGCTTGAAAAAGCCATAAAAGAAGAAGCTTATGAAAAAGCGGCAGAGCTCAGAGATAAAATAAGAGAACTGGAAAAAGAA
CTAGGAAAGTAGGTGAGAAC

Downstream 100 bases:

>100_bases
TTTCGGGAGGTGTTAATATGGCCATGTTTGGCAGGTTTACAGAAAGGGCTCAAAAGGCTCTTTATCTAGCTCAAGAGGAA
GCAAGGTCTTTTTACCATAA

Product: ATP:guanido phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLQYDKDVVLSSRIRLARNVKDIPFPTVMTEEQGKKVIELARKAILGSNTILSTQFTEYEMKKLTPLDRQALVEKHLISP
DLSQNIKTGYALIKDDNTVSIMVNEEDHLRIQCILPGLKLDESWDMADKIDDLIEETIDYAYDEKIGYLTSCPTNVGTGI
RASVMVHLPALTITGQISNILNSVSKIGMAVRGIYGEGTQALGDIYQISNQVTLGQSEKEIIENIEGVAKQIISSERRAR
EELYKKQRVQIEDRVGRAFGILSHAKVMSTKEYMTLMSDVRLGIVLGILSVDLDKLDRLTTQIQPANLQKIYGMQLNPYE
RDVKRAEYVSTQLNKKE

Sequences:

>Translated_337_residues
MLQYDKDVVLSSRIRLARNVKDIPFPTVMTEEQGKKVIELARKAILGSNTILSTQFTEYEMKKLTPLDRQALVEKHLISP
DLSQNIKTGYALIKDDNTVSIMVNEEDHLRIQCILPGLKLDESWDMADKIDDLIEETIDYAYDEKIGYLTSCPTNVGTGI
RASVMVHLPALTITGQISNILNSVSKIGMAVRGIYGEGTQALGDIYQISNQVTLGQSEKEIIENIEGVAKQIISSERRAR
EELYKKQRVQIEDRVGRAFGILSHAKVMSTKEYMTLMSDVRLGIVLGILSVDLDKLDRLTTQIQPANLQKIYGMQLNPYE
RDVKRAEYVSTQLNKKE
>Mature_337_residues
MLQYDKDVVLSSRIRLARNVKDIPFPTVMTEEQGKKVIELARKAILGSNTILSTQFTEYEMKKLTPLDRQALVEKHLISP
DLSQNIKTGYALIKDDNTVSIMVNEEDHLRIQCILPGLKLDESWDMADKIDDLIEETIDYAYDEKIGYLTSCPTNVGTGI
RASVMVHLPALTITGQISNILNSVSKIGMAVRGIYGEGTQALGDIYQISNQVTLGQSEKEIIENIEGVAKQIISSERRAR
EELYKKQRVQIEDRVGRAFGILSHAKVMSTKEYMTLMSDVRLGIVLGILSVDLDKLDRLTTQIQPANLQKIYGMQLNPYE
RDVKRAEYVSTQLNKKE

Specific function: Unknown

COG id: COG3869

COG function: function code E; Arginine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 phosphagen kinase C-terminal domain

Homologues:

Organism=Homo sapiens, GI153252003, Length=252, Percent_Identity=27.7777777777778, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI153251984, Length=252, Percent_Identity=27.7777777777778, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI153251982, Length=252, Percent_Identity=27.7777777777778, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI66346730, Length=251, Percent_Identity=27.0916334661355, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI10334859, Length=251, Percent_Identity=27.0916334661355, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI21536286, Length=250, Percent_Identity=27.6, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI310110654, Length=250, Percent_Identity=27.6, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI21536288, Length=252, Percent_Identity=26.5873015873016, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI310110650, Length=187, Percent_Identity=28.3422459893048, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI310110652, Length=149, Percent_Identity=31.5436241610738, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17509681, Length=255, Percent_Identity=28.2352941176471, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17507069, Length=255, Percent_Identity=28.2352941176471, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17560974, Length=253, Percent_Identity=28.4584980237154, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17511011, Length=242, Percent_Identity=28.5123966942149, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71990551, Length=240, Percent_Identity=27.5, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566409, Length=240, Percent_Identity=27.5, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24661332, Length=253, Percent_Identity=32.4110671936759, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI161082598, Length=241, Percent_Identity=28.2157676348548, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221331031, Length=241, Percent_Identity=28.2157676348548, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24661348, Length=241, Percent_Identity=28.2157676348548, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24661344, Length=241, Percent_Identity=28.2157676348548, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24661336, Length=241, Percent_Identity=28.2157676348548, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24661340, Length=241, Percent_Identity=28.2157676348548, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647265, Length=252, Percent_Identity=28.968253968254, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2328_THETN (Q8R7S0)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623865.1
- ProteinModelPortal:   Q8R7S0
- SMR:   Q8R7S0
- GeneID:   997417
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2328
- NMPDR:   fig|273068.3.peg.2505
- HOGENOM:   HBG302740
- OMA:   IRASVMM
- ProtClustDB:   PRK01059
- BioCyc:   TTEN273068:TTE2328-MONOMER
- HAMAP:   MF_00602
- InterPro:   IPR000749
- InterPro:   IPR022414
- InterPro:   IPR022415
- InterPro:   IPR014746
- Gene3D:   G3DSA:3.30.590.10
- PANTHER:   PTHR11547

Pfam domain/function: PF00217 ATP-gua_Ptrans

EC number: NA

Molecular weight: Translated: 38009; Mature: 38009

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00112 PHOSPHAGEN_KINASE; PS51510 PHOSPHAGEN_KINASE_C

Important sites: BINDING 76-76 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQYDKDVVLSSRIRLARNVKDIPFPTVMTEEQGKKVIELARKAILGSNTILSTQFTEYE
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEECCCHHHH
MKKLTPLDRQALVEKHLISPDLSQNIKTGYALIKDDNTVSIMVNEEDHLRIQCILPGLKL
HHHCCCCHHHHHHHHHHCCCCHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEEECCCCC
DESWDMADKIDDLIEETIDYAYDEKIGYLTSCPTNVGTGIRASVMVHLPALTITGQISNI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEEECCEEEHHHHHHH
LNSVSKIGMAVRGIYGEGTQALGDIYQISNQVTLGQSEKEIIENIEGVAKQIISSERRAR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EELYKKQRVQIEDRVGRAFGILSHAKVMSTKEYMTLMSDVRLGIVLGILSVDLDKLDRLT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
TQIQPANLQKIYGMQLNPYERDVKRAEYVSTQLNKKE
HHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLQYDKDVVLSSRIRLARNVKDIPFPTVMTEEQGKKVIELARKAILGSNTILSTQFTEYE
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEECCCHHHH
MKKLTPLDRQALVEKHLISPDLSQNIKTGYALIKDDNTVSIMVNEEDHLRIQCILPGLKL
HHHCCCCHHHHHHHHHHCCCCHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEEECCCCC
DESWDMADKIDDLIEETIDYAYDEKIGYLTSCPTNVGTGIRASVMVHLPALTITGQISNI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEEECCEEEHHHHHHH
LNSVSKIGMAVRGIYGEGTQALGDIYQISNQVTLGQSEKEIIENIEGVAKQIISSERRAR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EELYKKQRVQIEDRVGRAFGILSHAKVMSTKEYMTLMSDVRLGIVLGILSVDLDKLDRLT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
TQIQPANLQKIYGMQLNPYERDVKRAEYVSTQLNKKE
HHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336