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The map label for this gene is Sms [H]

Identifier: 20808691

GI number: 20808691

Start: 2205876

End: 2207240

Strand: Reverse

Name: Sms [H]

Synonym: TTE2325

Alternate gene names: 20808691

Gene position: 2207240-2205876 (Counterclockwise)

Preceding gene: 20808692

Following gene: 20808689

Centisome position: 82.07

GC content: 41.68

Gene sequence:

>1365_bases
TTGAAAGATGGTGGAGAGATGAAGAAGTCGACCACAAAATTTGTATGCAGAGAATGCGGATTTGAGAGCAGTAAATGGCT
GGGCAGATGCCCTAATTGCGGCAGCTGGAATTCTTTTGATGAAGAGATAGTAGGGGATTTCAAAGAAAAAAAGGTTAAAA
GCAGGAATAGCAAAAACTTATACTTGTTAAGAGAGGTTGTATCTTCTGAAGAAGAGAGGATAAAGACAGGTATTGAAGAA
TTTGACAGAGTACTAGGGGGCGGCATTGTAAGAGGTTCCTTGGTGCTCATAGGAGGAGACCCAGGGATAGGGAAGTCAAC
GCTTTTGCTTCAGGTAGCTGGAAATGTTTCAGAAAAGTTTACGGTGTTATATGTATCTGGTGAGGAATCCCCCCAGCAAA
TCAAGCTGAGGGCTGATAGAATTTTAAAAGAGAGGCAGGATTTATACCTTTTGTGTGAGACGAATATAGATGTGATAGAG
GAAAAAATTGAAGAGATACGTCCGGATTTTGTGATAGTAGATTCTATTCAGACCATGTACACAGAGGAAAGTGAGACAAT
ACCTGGCAGCATTTCTCAGGTGAGATACGCTTCTCAAAAGCTTATGGCTATTGCGAAAGAAAAAAATATAAGCGTTTTTT
TGATAGGGCATGTCACAAAGGAAGGAGCTATAGCAGGGCCCAAGGTTCTTGAACACATGGTGGACACGGTTCTCTATTTG
GAGGGCGATGCCAGCCATTCTTTTAGAGTGTTAAGGGCTGTTAAAAATAGGTTTGGAGCAACTCACGAAATAGGAGTTTT
TGAGATGCAAGATAAAGGGCTTGAGGAAATCCGCAATCCCTCTGAATTTATACTGATGAGCAGGCCTAAAGGGGTTGCCG
GTACAGCGATTGTGTCTTCTCTCCAGGGGACGCGCCCTATTTTGATGGAAGTTCAGGCGCTTTTGAGCTACACATCTTTT
GGTATGCCGAGGAGAATGGCGACAGGTTTTGATTACAACAGGTTTATTCTGCTTCTTGCGGTAATGGAAAAAAGATTGGG
GCTTAATTTTTCAAATTTTGATGCGTATGTAAATGTGACAGGGGGGATAAAAATTCAGGAGCCGGCAGCCGATTTGGGCG
TAATAGCTGCTTCTTTGTCAGGATATTATAACATCCCTTTGCCAGAGGATGTTTGTTTCGTCGGAGAAGTAGGTTTAGCT
GGAGAAGTAAGGGGTGTTGGCAATATTGACAAGAGAATCAACGAAGCTAAAAAGATGGGGTTTTCTAAGGTTTTTATACC
TCATATGAAAGCCAAAGAAGAAGGGATTGAGGTAATAAAGGTCAAAGATATAAAAGAGGTAATGGAATTTGTAAGAGGGT
TGTAA

Upstream 100 bases:

>100_bases
TGTTAGTGGCCTCTTTTGTGATGATATTGAACGGGTTACTTCTTTATTTAACTTTAAAGGGAGAAGTTTAAGTGGTATAA
TTTAAACAAGCAAAGCATTT

Downstream 100 bases:

>100_bases
AAAAAGCGCCTTAAAAGGCGCTTCTTATAACATGTTAAAAATTCCTAGAGTATTTAGCTCTTTGTGCTTTTTAAGGAGTA
TGTCGTAAAAATTAAGGCCT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKDGGEMKKSTTKFVCRECGFESSKWLGRCPNCGSWNSFDEEIVGDFKEKKVKSRNSKNLYLLREVVSSEEERIKTGIEE
FDRVLGGGIVRGSLVLIGGDPGIGKSTLLLQVAGNVSEKFTVLYVSGEESPQQIKLRADRILKERQDLYLLCETNIDVIE
EKIEEIRPDFVIVDSIQTMYTEESETIPGSISQVRYASQKLMAIAKEKNISVFLIGHVTKEGAIAGPKVLEHMVDTVLYL
EGDASHSFRVLRAVKNRFGATHEIGVFEMQDKGLEEIRNPSEFILMSRPKGVAGTAIVSSLQGTRPILMEVQALLSYTSF
GMPRRMATGFDYNRFILLLAVMEKRLGLNFSNFDAYVNVTGGIKIQEPAADLGVIAASLSGYYNIPLPEDVCFVGEVGLA
GEVRGVGNIDKRINEAKKMGFSKVFIPHMKAKEEGIEVIKVKDIKEVMEFVRGL

Sequences:

>Translated_454_residues
MKDGGEMKKSTTKFVCRECGFESSKWLGRCPNCGSWNSFDEEIVGDFKEKKVKSRNSKNLYLLREVVSSEEERIKTGIEE
FDRVLGGGIVRGSLVLIGGDPGIGKSTLLLQVAGNVSEKFTVLYVSGEESPQQIKLRADRILKERQDLYLLCETNIDVIE
EKIEEIRPDFVIVDSIQTMYTEESETIPGSISQVRYASQKLMAIAKEKNISVFLIGHVTKEGAIAGPKVLEHMVDTVLYL
EGDASHSFRVLRAVKNRFGATHEIGVFEMQDKGLEEIRNPSEFILMSRPKGVAGTAIVSSLQGTRPILMEVQALLSYTSF
GMPRRMATGFDYNRFILLLAVMEKRLGLNFSNFDAYVNVTGGIKIQEPAADLGVIAASLSGYYNIPLPEDVCFVGEVGLA
GEVRGVGNIDKRINEAKKMGFSKVFIPHMKAKEEGIEVIKVKDIKEVMEFVRGL
>Mature_454_residues
MKDGGEMKKSTTKFVCRECGFESSKWLGRCPNCGSWNSFDEEIVGDFKEKKVKSRNSKNLYLLREVVSSEEERIKTGIEE
FDRVLGGGIVRGSLVLIGGDPGIGKSTLLLQVAGNVSEKFTVLYVSGEESPQQIKLRADRILKERQDLYLLCETNIDVIE
EKIEEIRPDFVIVDSIQTMYTEESETIPGSISQVRYASQKLMAIAKEKNISVFLIGHVTKEGAIAGPKVLEHMVDTVLYL
EGDASHSFRVLRAVKNRFGATHEIGVFEMQDKGLEEIRNPSEFILMSRPKGVAGTAIVSSLQGTRPILMEVQALLSYTSF
GMPRRMATGFDYNRFILLLAVMEKRLGLNFSNFDAYVNVTGGIKIQEPAADLGVIAASLSGYYNIPLPEDVCFVGEVGLA
GEVRGVGNIDKRINEAKKMGFSKVFIPHMKAKEEGIEVIKVKDIKEVMEFVRGL

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=455, Percent_Identity=40.8791208791209, Blast_Score=376, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 50432; Mature: 50432

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDGGEMKKSTTKFVCRECGFESSKWLGRCPNCGSWNSFDEEIVGDFKEKKVKSRNSKNL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
YLLREVVSSEEERIKTGIEEFDRVLGGGIVRGSLVLIGGDPGIGKSTLLLQVAGNVSEKF
HHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCCCCCCEEEEEECCCCCCEE
TVLYVSGEESPQQIKLRADRILKERQDLYLLCETNIDVIEEKIEEIRPDFVIVDSIQTMY
EEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECHHHHH
TEESETIPGSISQVRYASQKLMAIAKEKNISVFLIGHVTKEGAIAGPKVLEHMVDTVLYL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHEEEE
EGDASHSFRVLRAVKNRFGATHEIGVFEMQDKGLEEIRNPSEFILMSRPKGVAGTAIVSS
ECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCCCCCEEEEECCCCCHHHHHHHH
LQGTRPILMEVQALLSYTSFGMPRRMATGFDYNRFILLLAVMEKRLGLNFSNFDAYVNVT
HCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
GGIKIQEPAADLGVIAASLSGYYNIPLPEDVCFVGEVGLAGEVRGVGNIDKRINEAKKMG
CCEEECCCCHHHHHHHHHHCCEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
FSKVFIPHMKAKEEGIEVIKVKDIKEVMEFVRGL
CCCEECCCCCCHHCCCEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKDGGEMKKSTTKFVCRECGFESSKWLGRCPNCGSWNSFDEEIVGDFKEKKVKSRNSKNL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
YLLREVVSSEEERIKTGIEEFDRVLGGGIVRGSLVLIGGDPGIGKSTLLLQVAGNVSEKF
HHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCCCCCCEEEEEECCCCCCEE
TVLYVSGEESPQQIKLRADRILKERQDLYLLCETNIDVIEEKIEEIRPDFVIVDSIQTMY
EEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECHHHHH
TEESETIPGSISQVRYASQKLMAIAKEKNISVFLIGHVTKEGAIAGPKVLEHMVDTVLYL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHEEEE
EGDASHSFRVLRAVKNRFGATHEIGVFEMQDKGLEEIRNPSEFILMSRPKGVAGTAIVSS
ECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCCCCCEEEEECCCCCHHHHHHHH
LQGTRPILMEVQALLSYTSFGMPRRMATGFDYNRFILLLAVMEKRLGLNFSNFDAYVNVT
HCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
GGIKIQEPAADLGVIAASLSGYYNIPLPEDVCFVGEVGLAGEVRGVGNIDKRINEAKKMG
CCEEECCCCHHHHHHHHHHCCEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
FSKVFIPHMKAKEEGIEVIKVKDIKEVMEFVRGL
CCCEECCCCCCHHCCCEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]