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The map label for this gene is MviM4 [H]

Identifier: 20808355

GI number: 20808355

Start: 1897606

End: 1898694

Strand: Reverse

Name: MviM4 [H]

Synonym: TTE1951

Alternate gene names: 20808355

Gene position: 1898694-1897606 (Counterclockwise)

Preceding gene: 20808356

Following gene: 20808354

Centisome position: 70.6

GC content: 46.01

Gene sequence:

>1089_bases
ATGTCCAAGGAAAAAGTGAGAGTAGGAATAATTGGTTGCGGAGGGATAGCTTTTGGAAAGCACATGCCCTCTTTGGCAAA
GCTTGATAACGTTGAAATGGTGGCCTTTTGCGACATCATAGAGGAGAGGGCTAGGAAGGCAGCAAAGGAATACGGAACAG
ACGATGCGAAAGTGTACACAGATTACAGAAAGCTTTTAGAAGACAAGACTATAGACGTAGTGCACGTCTGCACACCGAAT
AAGTCTCATGCAGGCATAACTGTGGATGCTCTTTACGCCGGAAAGCATGTAATGTGTGAAAAGCCAATGGCAAAGACTGC
AGAAGGCGCAAGAAAGATGGTAGAAGCTTATAAGAAGACAGGCAAAAAGCTTACAATAGGGTATCAGAATCGCTTCAGGC
CAGATTCGCAGTATTTACATAAGATTTGCCAGAATGGAGAGCTTGGCGAAGTTTATTTTGCAAAGGCATATGCAGTGAGG
CGCCGTGCTGTTCCCACATGGGGGGTTTTCTTGGATGAAGAAGAGCAGGGAGGAGGTCCTCTAATCGATATAGGAACCCA
TTCTCTCGATTTAACCCTTTGGATGATGAACAATTACAAGCCTAGGATGGTGGTTGGCACAGTGTACCACAAACTTGGCA
AGATGGCAAACGCGGCAAACGCATGGGGACCATGGGACCCTGAAAAATTCACAGTAGAAGATTCTGCCTTTGGGTTTATA
GTCATGGAAAATGGCGCTACCATCATATTAGAATCCAGCTGGGCTTTGAACACACTGGATGTCGGGGAAGCGATGACGAC
TCTCTGCGGGACAGAAGGCGGAGCCGATATGAGAGATGGGCTTCGCATAAATGGCGAGAGGTTTGGACGCCTTTACACTA
CAAAAGTATCTTTTGACATAGGCGGTGTCGCGTATTACGAAGGGAAAGGAGAAGACCCCGGGTATCTGGAAGCCAAGTCC
TGGATAGATGCCATTGTAAATGACAGAGAACCGGTTGTAAAGCCAGAAGAAGCTTTGGTGGTAAGCGAGATATTAGAGGC
TATTTACACATCAGCTAAGACAGGAAAGCCTGTATACTTTAATAAGTAA

Upstream 100 bases:

>100_bases
TTTCTGGAGCACGAGCTTGTTATAAGAGAGTCAACAGTCAAGTATTAAAAATTGCCCTTTGAGGCAATTTTCAAAATAAA
CAGCAAAGGGAGGAAGAAAA

Downstream 100 bases:

>100_bases
TGGAGGTTTATGTATGAAAAAACTCAGATACGCATGTGTCGGTGCAGGTGCAGTTGCTGATTACAAGCACCTACTCGGTT
ATTCAAGATTAAAAGATGTT

Product: dehydrogenase and related proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSKEKVRVGIIGCGGIAFGKHMPSLAKLDNVEMVAFCDIIEERARKAAKEYGTDDAKVYTDYRKLLEDKTIDVVHVCTPN
KSHAGITVDALYAGKHVMCEKPMAKTAEGARKMVEAYKKTGKKLTIGYQNRFRPDSQYLHKICQNGELGEVYFAKAYAVR
RRAVPTWGVFLDEEEQGGGPLIDIGTHSLDLTLWMMNNYKPRMVVGTVYHKLGKMANAANAWGPWDPEKFTVEDSAFGFI
VMENGATIILESSWALNTLDVGEAMTTLCGTEGGADMRDGLRINGERFGRLYTTKVSFDIGGVAYYEGKGEDPGYLEAKS
WIDAIVNDREPVVKPEEALVVSEILEAIYTSAKTGKPVYFNK

Sequences:

>Translated_362_residues
MSKEKVRVGIIGCGGIAFGKHMPSLAKLDNVEMVAFCDIIEERARKAAKEYGTDDAKVYTDYRKLLEDKTIDVVHVCTPN
KSHAGITVDALYAGKHVMCEKPMAKTAEGARKMVEAYKKTGKKLTIGYQNRFRPDSQYLHKICQNGELGEVYFAKAYAVR
RRAVPTWGVFLDEEEQGGGPLIDIGTHSLDLTLWMMNNYKPRMVVGTVYHKLGKMANAANAWGPWDPEKFTVEDSAFGFI
VMENGATIILESSWALNTLDVGEAMTTLCGTEGGADMRDGLRINGERFGRLYTTKVSFDIGGVAYYEGKGEDPGYLEAKS
WIDAIVNDREPVVKPEEALVVSEILEAIYTSAKTGKPVYFNK
>Mature_361_residues
SKEKVRVGIIGCGGIAFGKHMPSLAKLDNVEMVAFCDIIEERARKAAKEYGTDDAKVYTDYRKLLEDKTIDVVHVCTPNK
SHAGITVDALYAGKHVMCEKPMAKTAEGARKMVEAYKKTGKKLTIGYQNRFRPDSQYLHKICQNGELGEVYFAKAYAVRR
RAVPTWGVFLDEEEQGGGPLIDIGTHSLDLTLWMMNNYKPRMVVGTVYHKLGKMANAANAWGPWDPEKFTVEDSAFGFIV
MENGATIILESSWALNTLDVGEAMTTLCGTEGGADMRDGLRINGERFGRLYTTKVSFDIGGVAYYEGKGEDPGYLEAKSW
IDAIVNDREPVVKPEEALVVSEILEAIYTSAKTGKPVYFNK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=202, Percent_Identity=28.2178217821782, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1787574, Length=358, Percent_Identity=35.4748603351955, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI87081947, Length=191, Percent_Identity=29.3193717277487, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581117, Length=211, Percent_Identity=27.0142180094787, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40114; Mature: 39983

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKVRVGIIGCGGIAFGKHMPSLAKLDNVEMVAFCDIIEERARKAAKEYGTDDAKVYT
CCCCEEEEEEEEECCHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DYRKLLEDKTIDVVHVCTPNKSHAGITVDALYAGKHVMCEKPMAKTAEGARKMVEAYKKT
HHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHC
GKKLTIGYQNRFRPDSQYLHKICQNGELGEVYFAKAYAVRRRAVPTWGVFLDEEEQGGGP
CCEEEEECCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCEEEECCCCCCCC
LIDIGTHSLDLTLWMMNNYKPRMVVGTVYHKLGKMANAANAWGPWDPEKFTVEDSAFGFI
EEEECCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEE
VMENGATIILESSWALNTLDVGEAMTTLCGTEGGADMRDGLRINGERFGRLYTTKVSFDI
EEECCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCHHCCEEEEEEEEEEE
GGVAYYEGKGEDPGYLEAKSWIDAIVNDREPVVKPEEALVVSEILEAIYTSAKTGKPVYF
CCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEE
NK
CC
>Mature Secondary Structure 
SKEKVRVGIIGCGGIAFGKHMPSLAKLDNVEMVAFCDIIEERARKAAKEYGTDDAKVYT
CCCEEEEEEEEECCHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DYRKLLEDKTIDVVHVCTPNKSHAGITVDALYAGKHVMCEKPMAKTAEGARKMVEAYKKT
HHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHC
GKKLTIGYQNRFRPDSQYLHKICQNGELGEVYFAKAYAVRRRAVPTWGVFLDEEEQGGGP
CCEEEEECCCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCEEEECCCCCCCC
LIDIGTHSLDLTLWMMNNYKPRMVVGTVYHKLGKMANAANAWGPWDPEKFTVEDSAFGFI
EEEECCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEE
VMENGATIILESSWALNTLDVGEAMTTLCGTEGGADMRDGLRINGERFGRLYTTKVSFDI
EEECCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCHHCCEEEEEEEEEEE
GGVAYYEGKGEDPGYLEAKSWIDAIVNDREPVVKPEEALVVSEILEAIYTSAKTGKPVYF
CCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEE
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]