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The map label for this gene is MviM3 [H]

Identifier: 20808354

GI number: 20808354

Start: 1896546

End: 1897592

Strand: Reverse

Name: MviM3 [H]

Synonym: TTE1950

Alternate gene names: 20808354

Gene position: 1897592-1896546 (Counterclockwise)

Preceding gene: 20808355

Following gene: 20808353

Centisome position: 70.56

GC content: 38.01

Gene sequence:

>1047_bases
ATGAAAAAACTCAGATACGCATGTGTCGGTGCAGGTGCAGTTGCTGATTACAAGCACCTACTCGGTTATTCAAGATTAAA
AGATGTTGAAATTGTAGCCATATCTGACCCGGATGTTGGGGCGGCTAAGAGGCTGGCAGAGAAGTACAGTATTCCTCATG
TTTACGAAAACTATGAAGAAATGTTTGAAAAAGAAAAACTTGATCTAATTAGCATATGTACTCCTAATTATTTGCATGCC
CCTATTTCTATAAAAGCGATGGAGAAGGGAATTCACATCCACTGCGAAAAGCCCATGACTTTAAATGCCAAAGAGGCCCA
CAAAGTAATTGAAGCGAAGAATAAATACAAGACAAAATTTATGGTGGGATTAAATAACAGATTTACAAACGAATCTTACT
TTGTAAAAAAGTACATAGAAGAAGGCTATCTTGGAGAAATATACCATGTAAAGACGGGATGGAGGAGGAGAAGAGGCATT
CCGGGTAAAGGCGGATGGTTTACCACAAAAAAATTATCTGGAGGAGGGCCTTTGATAGATTTGGGCGTGCATTTTATTGA
CCTGGTCATGTATTTTATGGATTATCCGGAGGTTAAGTCCGTTTCAGCAGCTACCTACTCTAAATTTTCAAATAGTACTA
GCTGGAATGGATGGAGTGAAGCAAAATCAGGCAATGGCATTTACAATGTAGAGGATATGGCAGTGGGATTTATAAGACTT
AAAAATGGTACTACAATTGACTTTGAATTTAGCTGGGCCTCCAATATTGAGGGAGATTACAACTACTATGAAATTTTAGG
AGATAAAGGCGGTATATGGTTCAAAAATGGTCAGATAAAGGTATTTTCAGAAGTTGTGAATACTTTAGTGGACATAATAC
CAAATACAAACTATCCCAAGAAGCCTTTAGACGAGTTTGAACACTTTGTAAACTGCATAAAAGAAGGTAAAGAACCTTTG
GCTTCAGCGGAAGAGGGAGCAAAACTTATGGAAATAATAGATGCGGCGTATCTGTCCGCTGAAAAGGGAGTTGAAATAGT
TCTTTAA

Upstream 100 bases:

>100_bases
CCAGAAGAAGCTTTGGTGGTAAGCGAGATATTAGAGGCTATTTACACATCAGCTAAGACAGGAAAGCCTGTATACTTTAA
TAAGTAATGGAGGTTTATGT

Downstream 100 bases:

>100_bases
GGGGGAAGTTAGGATGCTACCTATTGCGCTTCAGCTTTATACTGTTAGGGAAGAAGCACAGAAAGACTTTACAGGCACTC
TTGAAAAAGTGGCAGAGATG

Product: dehydrogenase and related proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKKLRYACVGAGAVADYKHLLGYSRLKDVEIVAISDPDVGAAKRLAEKYSIPHVYENYEEMFEKEKLDLISICTPNYLHA
PISIKAMEKGIHIHCEKPMTLNAKEAHKVIEAKNKYKTKFMVGLNNRFTNESYFVKKYIEEGYLGEIYHVKTGWRRRRGI
PGKGGWFTTKKLSGGGPLIDLGVHFIDLVMYFMDYPEVKSVSAATYSKFSNSTSWNGWSEAKSGNGIYNVEDMAVGFIRL
KNGTTIDFEFSWASNIEGDYNYYEILGDKGGIWFKNGQIKVFSEVVNTLVDIIPNTNYPKKPLDEFEHFVNCIKEGKEPL
ASAEEGAKLMEIIDAAYLSAEKGVEIVL

Sequences:

>Translated_348_residues
MKKLRYACVGAGAVADYKHLLGYSRLKDVEIVAISDPDVGAAKRLAEKYSIPHVYENYEEMFEKEKLDLISICTPNYLHA
PISIKAMEKGIHIHCEKPMTLNAKEAHKVIEAKNKYKTKFMVGLNNRFTNESYFVKKYIEEGYLGEIYHVKTGWRRRRGI
PGKGGWFTTKKLSGGGPLIDLGVHFIDLVMYFMDYPEVKSVSAATYSKFSNSTSWNGWSEAKSGNGIYNVEDMAVGFIRL
KNGTTIDFEFSWASNIEGDYNYYEILGDKGGIWFKNGQIKVFSEVVNTLVDIIPNTNYPKKPLDEFEHFVNCIKEGKEPL
ASAEEGAKLMEIIDAAYLSAEKGVEIVL
>Mature_348_residues
MKKLRYACVGAGAVADYKHLLGYSRLKDVEIVAISDPDVGAAKRLAEKYSIPHVYENYEEMFEKEKLDLISICTPNYLHA
PISIKAMEKGIHIHCEKPMTLNAKEAHKVIEAKNKYKTKFMVGLNNRFTNESYFVKKYIEEGYLGEIYHVKTGWRRRRGI
PGKGGWFTTKKLSGGGPLIDLGVHFIDLVMYFMDYPEVKSVSAATYSKFSNSTSWNGWSEAKSGNGIYNVEDMAVGFIRL
KNGTTIDFEFSWASNIEGDYNYYEILGDKGGIWFKNGQIKVFSEVVNTLVDIIPNTNYPKKPLDEFEHFVNCIKEGKEPL
ASAEEGAKLMEIIDAAYLSAEKGVEIVL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=194, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787574, Length=348, Percent_Identity=33.6206896551724, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87082405, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081947, Length=223, Percent_Identity=23.7668161434978, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581117, Length=198, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39332; Mature: 39332

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLRYACVGAGAVADYKHLLGYSRLKDVEIVAISDPDVGAAKRLAEKYSIPHVYENYEE
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHH
MFEKEKLDLISICTPNYLHAPISIKAMEKGIHIHCEKPMTLNAKEAHKVIEAKNKYKTKF
HHHHHCCCEEEECCCCCEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEE
MVGLNNRFTNESYFVKKYIEEGYLGEIYHVKTGWRRRRGIPGKGGWFTTKKLSGGGPLID
EEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCCCEEEEEEECCCCCCHH
LGVHFIDLVMYFMDYPEVKSVSAATYSKFSNSTSWNGWSEAKSGNGIYNVEDMAVGFIRL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHEEEEEEE
KNGTTIDFEFSWASNIEGDYNYYEILGDKGGIWFKNGQIKVFSEVVNTLVDIIPNTNYPK
CCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCCC
KPLDEFEHFVNCIKEGKEPLASAEEGAKLMEIIDAAYLSAEKGVEIVL
CHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure
MKKLRYACVGAGAVADYKHLLGYSRLKDVEIVAISDPDVGAAKRLAEKYSIPHVYENYEE
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHH
MFEKEKLDLISICTPNYLHAPISIKAMEKGIHIHCEKPMTLNAKEAHKVIEAKNKYKTKF
HHHHHCCCEEEECCCCCEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEE
MVGLNNRFTNESYFVKKYIEEGYLGEIYHVKTGWRRRRGIPGKGGWFTTKKLSGGGPLID
EEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHCCCCCCCCEEEEEEECCCCCCHH
LGVHFIDLVMYFMDYPEVKSVSAATYSKFSNSTSWNGWSEAKSGNGIYNVEDMAVGFIRL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHEEEEEEE
KNGTTIDFEFSWASNIEGDYNYYEILGDKGGIWFKNGQIKVFSEVVNTLVDIIPNTNYPK
CCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCCC
KPLDEFEHFVNCIKEGKEPLASAEEGAKLMEIIDAAYLSAEKGVEIVL
CHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]