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The map label for this gene is IolE2 [H]

Identifier: 20808353

GI number: 20808353

Start: 1895786

End: 1896532

Strand: Reverse

Name: IolE2 [H]

Synonym: TTE1949

Alternate gene names: 20808353

Gene position: 1896532-1895786 (Counterclockwise)

Preceding gene: 20808354

Following gene: 20808352

Centisome position: 70.52

GC content: 38.69

Gene sequence:

>747_bases
ATGCTACCTATTGCGCTTCAGCTTTATACTGTTAGGGAAGAAGCACAGAAAGACTTTACAGGCACTCTTGAAAAAGTGGC
AGAGATGGGATATGAAGGTGTAGAATTTGCAGGATATGGCGGATTAAAGGCAAGCGAACTTAAAAAGGTTTTAGATAGGA
CTGGTCTTAAGGCAGCCGGGTCGCATGTGGGTATAGAGTTACTGAAGAAGGATTTAAACGGAGTTTTAGAGTATAGCCTT
GAAATAGGGAACAGGTATATAGTGTGTCCCGGCGTTCCCTATAAATCAAAAGAGGACTATATTGAGATGGCAAAGTTTTT
CAATGAAGTAGGGGAAAGGTGCAAAGAAAAAGGGCTTATTTTCTGCTATCACAATCACGCCCATGAATTTGAAATTTATG
ATGGAGAATACGGCCTTGATATACTTTTTAAGAATACGGATAAAGAGTCAGTGAAAGCAGAAATTGATGTCTACTGGGTA
AAATACGCTGGAGTAGACCCTCTCGAATATTTAAAGAAATTTTCTGGAAGGCTTCCTCTCATTCATTTAAAAGATATGGA
TGGAAAGGATAGGAGCAATACAGAGATAGGGAATGGAATAATTGACTTTAAAAAGATAGTAAAAGTTGCAGAAGAAAATG
GTGTGGAGTGGCTGATTGTTGAGCAGGATGAGTGCAAAAGGTCTCCCCTTGAGAGTGCAAAAATAAGCCTTGAGAATTTA
AGAAGGATTTTAAAGGAGGAATTGTAA

Upstream 100 bases:

>100_bases
GCTTCAGCGGAAGAGGGAGCAAAACTTATGGAAATAATAGATGCGGCGTATCTGTCCGCTGAAAAGGGAGTTGAAATAGT
TCTTTAAGGGGGAAGTTAGG

Downstream 100 bases:

>100_bases
TTATGTATATAGGATTTTTAACAGTGGCTTTAAGAGACATGCCTTTAAAAGAAAAAGCCAAATGGGCGAGTGAAAATGGA
TTTAAATCCTTAGAAGTTGC

Product: sugar phosphate isomerase/epimerase

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAGSHVGIELLKKDLNGVLEYSL
EIGNRYIVCPGVPYKSKEDYIEMAKFFNEVGERCKEKGLIFCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWV
KYAGVDPLEYLKKFSGRLPLIHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAKISLENL
RRILKEEL

Sequences:

>Translated_248_residues
MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAGSHVGIELLKKDLNGVLEYSL
EIGNRYIVCPGVPYKSKEDYIEMAKFFNEVGERCKEKGLIFCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWV
KYAGVDPLEYLKKFSGRLPLIHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAKISLENL
RRILKEEL
>Mature_248_residues
MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAGSHVGIELLKKDLNGVLEYSL
EIGNRYIVCPGVPYKSKEDYIEMAKFFNEVGERCKEKGLIFCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWV
KYAGVDPLEYLKKFSGRLPLIHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAKISLENL
RRILKEEL

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 28255; Mature: 28255

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHCCCHHCC
SHVGIELLKKDLNGVLEYSLEIGNRYIVCPGVPYKSKEDYIEMAKFFNEVGERCKEKGLI
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
FCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWVKYAGVDPLEYLKKFSGRLPL
EEEECCCEEEEEECCCCCEEEEEECCCHHHHEEEEEEEEEEECCCCHHHHHHHHCCCCCE
IHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAKISLENL
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHCCCCHHHHHHHHHHH
RRILKEEL
HHHHHHCC
>Mature Secondary Structure
MLPIALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHCCCHHCC
SHVGIELLKKDLNGVLEYSLEIGNRYIVCPGVPYKSKEDYIEMAKFFNEVGERCKEKGLI
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
FCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWVKYAGVDPLEYLKKFSGRLPL
EEEECCCEEEEEECCCCCEEEEEECCCHHHHEEEEEEEEEEECCCCHHHHHHHHCCCCCE
IHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQDECKRSPLESAKISLENL
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHCCCCHHHHHHHHHHH
RRILKEEL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA