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The map label for this gene is MipB

Identifier: 20808323

GI number: 20808323

Start: 1856555

End: 1857205

Strand: Reverse

Name: MipB

Synonym: TTE1918

Alternate gene names: 20808323

Gene position: 1857205-1856555 (Counterclockwise)

Preceding gene: 20808327

Following gene: 20808322

Centisome position: 69.06

GC content: 40.86

Gene sequence:

>651_bases
ATGAAATTCTTTCTTGACACTGCAAATATAGAGGAGATAAAAGAGGCTTATTCTCTAGGAGTGATATCTGGGGTTACTAC
AAATCCGTCGCTTGTTGCCAAAGAGGGAAGGGATTTTAAAGAAGTAATAAGGGAGATAGCAGAGATTGTGGACGGGCCCA
TAAGCGCAGAGGTTATAAGCGATGACCATGAAGGGATGGTGAAAGAAGCAAGAGAGCTTGCAAAGATACATAAAAACATA
GTCATAAAAATACCCATGACGGCAGAGGGCCTGAAAGCTGTTAACATCCTTTCTAAAGAAGGAATTAAGACAAATGTGAC
ATTGATTTTTTCAGCAAATCAGGCGCTTCTCGCAGCTCGCGCTGGTGCTACCTATGTGAGTCCATTTGTAGGGAGACTGG
ACGACATAAATACGGATGGGATGCAGATAATTGAGGATATAGTAACTATATTCACAAACTATGATATACAGGCAGAAATA
ATAACTGCCAGCGTGAGACATCCTATACACGTTTTAGAGGCAGCAAAACTGGGAGCCCATATTGCTACAGTTCCTTACAA
AGTGCTCATGCAGATGATTAAGCATCCTCTCACAGATATAGGAATTGAAAGATTCAAAGAGGACTGGAAAAAAGCAGGAT
TGAAGATATGA

Upstream 100 bases:

>100_bases
TTCTACATTGTGCTTTTCCTTTTGACTTTAAGCTTTTAATTTTTGAAAGTTAGTTATATAATAAAGGTAAAGTTAAATTA
AACTGCGGAGGGATGAAAAT

Downstream 100 bases:

>100_bases
ATAAAAGGGCAGGGGAAAATCTCCCTGCCTTTTTAGTTATTTATAAGGCGGTGAGAGAATATAGTTTATTATGAGGTGAT
ATGATGTGAAAAAGGCCTTT

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKFFLDTANIEEIKEAYSLGVISGVTTNPSLVAKEGRDFKEVIREIAEIVDGPISAEVISDDHEGMVKEARELAKIHKNI
VIKIPMTAEGLKAVNILSKEGIKTNVTLIFSANQALLAARAGATYVSPFVGRLDDINTDGMQIIEDIVTIFTNYDIQAEI
ITASVRHPIHVLEAAKLGAHIATVPYKVLMQMIKHPLTDIGIERFKEDWKKAGLKI

Sequences:

>Translated_216_residues
MKFFLDTANIEEIKEAYSLGVISGVTTNPSLVAKEGRDFKEVIREIAEIVDGPISAEVISDDHEGMVKEARELAKIHKNI
VIKIPMTAEGLKAVNILSKEGIKTNVTLIFSANQALLAARAGATYVSPFVGRLDDINTDGMQIIEDIVTIFTNYDIQAEI
ITASVRHPIHVLEAAKLGAHIATVPYKVLMQMIKHPLTDIGIERFKEDWKKAGLKI
>Mature_216_residues
MKFFLDTANIEEIKEAYSLGVISGVTTNPSLVAKEGRDFKEVIREIAEIVDGPISAEVISDDHEGMVKEARELAKIHKNI
VIKIPMTAEGLKAVNILSKEGIKTNVTLIFSANQALLAARAGATYVSPFVGRLDDINTDGMQIIEDIVTIFTNYDIQAEI
ITASVRHPIHVLEAAKLGAHIATVPYKVLMQMIKHPLTDIGIERFKEDWKKAGLKI

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=174, Percent_Identity=31.6091954022989, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI87081788, Length=214, Percent_Identity=35.981308411215, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790382, Length=214, Percent_Identity=38.3177570093458, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1786189, Length=154, Percent_Identity=34.4155844155844, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788807, Length=183, Percent_Identity=31.1475409836066, Blast_Score=74, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25153750, Length=173, Percent_Identity=31.2138728323699, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321480, Length=171, Percent_Identity=32.1637426900585, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323386, Length=131, Percent_Identity=36.6412213740458, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45549185, Length=147, Percent_Identity=34.0136054421769, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_THETN (Q8R8S6)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623494.1
- ProteinModelPortal:   Q8R8S6
- SMR:   Q8R8S6
- GeneID:   997112
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1918
- NMPDR:   fig|273068.3.peg.1781
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- ProtClustDB:   PRK01362
- BioCyc:   TTEN273068:TTE1918-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23776; Mature: 23776

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFLDTANIEEIKEAYSLGVISGVTTNPSLVAKEGRDFKEVIREIAEIVDGPISAEVIS
CEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCHHEEC
DDHEGMVKEARELAKIHKNIVIKIPMTAEGLKAVNILSKEGIKTNVTLIFSANQALLAAR
CCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHH
AGATYVSPFVGRLDDINTDGMQIIEDIVTIFTNYDIQAEIITASVRHPIHVLEAAKLGAH
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHCHHHHHHHHHHCCH
IATVPYKVLMQMIKHPLTDIGIERFKEDWKKAGLKI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFFLDTANIEEIKEAYSLGVISGVTTNPSLVAKEGRDFKEVIREIAEIVDGPISAEVIS
CEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCCCHHEEC
DDHEGMVKEARELAKIHKNIVIKIPMTAEGLKAVNILSKEGIKTNVTLIFSANQALLAAR
CCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHH
AGATYVSPFVGRLDDINTDGMQIIEDIVTIFTNYDIQAEIITASVRHPIHVLEAAKLGAH
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHCHHHHHHHHHHCCH
IATVPYKVLMQMIKHPLTDIGIERFKEDWKKAGLKI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336