Click here to switch to the map view.

The map label for this gene is Fur5 [H]

Identifier: 20808265

GI number: 20808265

Start: 1798912

End: 1799400

Strand: Reverse

Name: Fur5 [H]

Synonym: TTE1851

Alternate gene names: 20808265

Gene position: 1799400-1798912 (Counterclockwise)

Preceding gene: 20808266

Following gene: 20808264

Centisome position: 66.91

GC content: 33.13

Gene sequence:

>489_bases
TTGGTGAGTTGTATGGTGAAAAATCAAAAAAACCTTATGCCTCTTTTAGTTAAGGTTCTAAAAGGTAGGGGCTTGAAGGT
TACGGAAAAGCGGCAGATCCTTTTGGATGTATTTTTAAAAAATCCGGATAAGCATTTTGATATTGATTCACTTTATGAAG
AAGTAAGGAAAAGGTGGCCTCACTATGGAATTGCTACTCTATACAGGAACTTAAAAATTTTAGTAGAAAGCGATATTATC
TCTGAAAATCTTATCGGAAACAAGAAATACTATGAGCTCAAGATGTTTAGCAAAAAAAGGATACACGCGCATTTAATCTG
CAAATACTGCGGTAATATTGACGAGTATTATAGCCCAGAGCTTATAAAAACTGTAAAAGAGATAGAAAAAAAGTATGACT
TTGATATTTACTATGGAGAACTAAATTTTTATGGAATATGCAGCAATTGCAAAGCCAGGCTTTTAGCAAATTCAGAGGAA
AAGTCTTAA

Upstream 100 bases:

>100_bases
GATAGATGATTTTCTGTGGGAGAAATGGAGAAAAATGTACGAAAGTTATTGACATATGTCAATAAAAATTGTATATTTAA
ATTGAACATATGTCTGAAAT

Downstream 100 bases:

>100_bases
AGTGCGGCGGGTTTCCGCGCTTTATTTTTTTATTGACTTGGATAGGTGACCATGATATACTAAATATTGAGGCATTAAAT
TAAGATACTACTATATTTTG

Product: Fe2+/Zn2+ uptake regulation proteins

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MVSCMVKNQKNLMPLLVKVLKGRGLKVTEKRQILLDVFLKNPDKHFDIDSLYEEVRKRWPHYGIATLYRNLKILVESDII
SENLIGNKKYYELKMFSKKRIHAHLICKYCGNIDEYYSPELIKTVKEIEKKYDFDIYYGELNFYGICSNCKARLLANSEE
KS

Sequences:

>Translated_162_residues
MVSCMVKNQKNLMPLLVKVLKGRGLKVTEKRQILLDVFLKNPDKHFDIDSLYEEVRKRWPHYGIATLYRNLKILVESDII
SENLIGNKKYYELKMFSKKRIHAHLICKYCGNIDEYYSPELIKTVKEIEKKYDFDIYYGELNFYGICSNCKARLLANSEE
KS
>Mature_162_residues
MVSCMVKNQKNLMPLLVKVLKGRGLKVTEKRQILLDVFLKNPDKHFDIDSLYEEVRKRWPHYGIATLYRNLKILVESDII
SENLIGNKKYYELKMFSKKRIHAHLICKYCGNIDEYYSPELIKTVKEIEKKYDFDIYYGELNFYGICSNCKARLLANSEE
KS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=136, Percent_Identity=30.1470588235294, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19183; Mature: 19183

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSCMVKNQKNLMPLLVKVLKGRGLKVTEKRQILLDVFLKNPDKHFDIDSLYEEVRKRWP
CCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
HYGIATLYRNLKILVESDIISENLIGNKKYYELKMFSKKRIHAHLICKYCGNIDEYYSPE
CCCHHHHHHHHHHEEEHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHCCCH
LIKTVKEIEKKYDFDIYYGELNFYGICSNCKARLLANSEEKS
HHHHHHHHHHHCCCEEEEECEEEEEECCCCHHHEECCCCCCC
>Mature Secondary Structure
MVSCMVKNQKNLMPLLVKVLKGRGLKVTEKRQILLDVFLKNPDKHFDIDSLYEEVRKRWP
CCEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
HYGIATLYRNLKILVESDIISENLIGNKKYYELKMFSKKRIHAHLICKYCGNIDEYYSPE
CCCHHHHHHHHHHEEEHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCHHCCCH
LIKTVKEIEKKYDFDIYYGELNFYGICSNCKARLLANSEEKS
HHHHHHHHHHHCCCEEEEECEEEEEECCCCHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8996110 [H]