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The map label for this gene is ManA [H]

Identifier: 20808170

GI number: 20808170

Start: 1697196

End: 1698155

Strand: Reverse

Name: ManA [H]

Synonym: TTE1751

Alternate gene names: 20808170

Gene position: 1698155-1697196 (Counterclockwise)

Preceding gene: 20808171

Following gene: 20808168

Centisome position: 63.14

GC content: 39.38

Gene sequence:

>960_bases
ATGGAACCTCTTAAGTTTAAGCCAATATTTATGGAGAGAATATGGGGAGGAACTGCTTTAAAAGAGAGGTTTGGGTTTGA
TATTCCTGAAGGCAAAAAAATAGGGGAACTCTGGACAGTGTCTGACAATAGGACGGCAGTTAGTGTAATTGATGGAGGAG
AATTTGACGGGAAAAAGATAAGCGATGTGGCGTTGGAATTTGCTGAAAGTCTCTATGGGAAGGGGAAAAAATACGAAAGG
TTTCCTCTCCTCATAAAAATCATAGATGCGCAGGATAAACTCTCAGTTCAAGTTCACCCTGATGACGAATACGCCTACAA
GTACGAAAATGGTGATTCGGGTAAGACAGAGATGTGGTACATAATAGATGCTAAGCCGGGTGCCAAATTGGTCTGTGGTC
TAAAAGAAGGTACCACAAGAGAAGAATTTATAAAACTTTTAGAAGAGGAAAGACTAGAAGAATGTCTAAAAGAAGTAGAA
GTCAAGGCGGGAGATGTTGTCTACATTCCTGCTGGGATGGTACATGCGATAGGCGAAGGCATTTTGATATGCGAAATTCA
GCAGAATTCCGATTTGACCTACAGGGTCTATGACTACAACAGAGTGGACGAAAAAGGCAGAAAAAGAGAGCTCCATGTAG
ATAAAGCACTTGATGTAATAGATTTTGAACTCAAATCAGATAAGATAGTGCCTATGTTTGAAGAAATAAAAGGAGGGCGT
ATTGCAAGAGCAGTTGAATCCCCATATTTTAACGTTGAGATAATTGAACTGGCTGAAAAAATGGAGTTTGAAACTTATGA
CAGATTTGAAACTCTTACTTCTGTGGAAGGCATATTAGAGGTAGAGTGGGAAGAAGGGACAAAAGTAGTAAAGGCAGGAG
AAACTATTGTCATACCCGCTTTTGTAGATAAATACAAAGTTAAAGGAAAAGCTAAATTTCTCAAAGCATATGTGCCGTGA

Upstream 100 bases:

>100_bases
CTTTCATGGACATGGTTAAGATTGCTCTGGAGATTGCATAGTAAAGTGGCATTTGAAAATGCCACTTTACTATTATCTAT
TTAGAAAGGAGAGATATTTT

Downstream 100 bases:

>100_bases
GTTTTATTAAAGTTTTGGCATTTTGAATTGCGCAGCCGTTGACGTCATTGTTGAAATACACGTAAATTTCATCGCAATTT
TTTAAATATTCTTCTATGTC

Product: phosphomannose isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MEPLKFKPIFMERIWGGTALKERFGFDIPEGKKIGELWTVSDNRTAVSVIDGGEFDGKKISDVALEFAESLYGKGKKYER
FPLLIKIIDAQDKLSVQVHPDDEYAYKYENGDSGKTEMWYIIDAKPGAKLVCGLKEGTTREEFIKLLEEERLEECLKEVE
VKAGDVVYIPAGMVHAIGEGILICEIQQNSDLTYRVYDYNRVDEKGRKRELHVDKALDVIDFELKSDKIVPMFEEIKGGR
IARAVESPYFNVEIIELAEKMEFETYDRFETLTSVEGILEVEWEEGTKVVKAGETIVIPAFVDKYKVKGKAKFLKAYVP

Sequences:

>Translated_319_residues
MEPLKFKPIFMERIWGGTALKERFGFDIPEGKKIGELWTVSDNRTAVSVIDGGEFDGKKISDVALEFAESLYGKGKKYER
FPLLIKIIDAQDKLSVQVHPDDEYAYKYENGDSGKTEMWYIIDAKPGAKLVCGLKEGTTREEFIKLLEEERLEECLKEVE
VKAGDVVYIPAGMVHAIGEGILICEIQQNSDLTYRVYDYNRVDEKGRKRELHVDKALDVIDFELKSDKIVPMFEEIKGGR
IARAVESPYFNVEIIELAEKMEFETYDRFETLTSVEGILEVEWEEGTKVVKAGETIVIPAFVDKYKVKGKAKFLKAYVP
>Mature_319_residues
MEPLKFKPIFMERIWGGTALKERFGFDIPEGKKIGELWTVSDNRTAVSVIDGGEFDGKKISDVALEFAESLYGKGKKYER
FPLLIKIIDAQDKLSVQVHPDDEYAYKYENGDSGKTEMWYIIDAKPGAKLVCGLKEGTTREEFIKLLEEERLEECLKEVE
VKAGDVVYIPAGMVHAIGEGILICEIQQNSDLTYRVYDYNRVDEKGRKRELHVDKALDVIDFELKSDKIVPMFEEIKGGR
IARAVESPYFNVEIIELAEKMEFETYDRFETLTSVEGILEVEWEEGTKVVKAGETIVIPAFVDKYKVKGKAKFLKAYVP

Specific function: Involved In The Conversion Of Glucose To Gdp-L-Fucose, Which Can Be Converted To L-Fucose, A Capsular Polysaccharide. [C]

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 36410; Mature: 36410

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLKFKPIFMERIWGGTALKERFGFDIPEGKKIGELWTVSDNRTAVSVIDGGEFDGKKI
CCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCHH
SDVALEFAESLYGKGKKYERFPLLIKIIDAQDKLSVQVHPDDEYAYKYENGDSGKTEMWY
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEEEECCCCCCCEEEEE
IIDAKPGAKLVCGLKEGTTREEFIKLLEEERLEECLKEVEVKAGDVVYIPAGMVHAIGEG
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCCC
ILICEIQQNSDLTYRVYDYNRVDEKGRKRELHVDKALDVIDFELKSDKIVPMFEEIKGGR
EEEEEEECCCCCEEEEEECCCCCCCCCCCEEEHHHHCCEEEEEECCCCCCCHHHHCCCCE
IARAVESPYFNVEIIELAEKMEFETYDRFETLTSVEGILEVEWEEGTKVVKAGETIVIPA
EEHHHCCCCCCEEHEEHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCEEEECCCEEEEEE
FVDKYKVKGKAKFLKAYVP
HHCCCCCCCHHEEEEECCC
>Mature Secondary Structure
MEPLKFKPIFMERIWGGTALKERFGFDIPEGKKIGELWTVSDNRTAVSVIDGGEFDGKKI
CCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCHH
SDVALEFAESLYGKGKKYERFPLLIKIIDAQDKLSVQVHPDDEYAYKYENGDSGKTEMWY
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEEEECCCCCCCEEEEE
IIDAKPGAKLVCGLKEGTTREEFIKLLEEERLEECLKEVEVKAGDVVYIPAGMVHAIGEG
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCCC
ILICEIQQNSDLTYRVYDYNRVDEKGRKRELHVDKALDVIDFELKSDKIVPMFEEIKGGR
EEEEEEECCCCCEEEEEECCCCCCCCCCCEEEHHHHCCEEEEEECCCCCCCHHHHCCCCE
IARAVESPYFNVEIIELAEKMEFETYDRFETLTSVEGILEVEWEEGTKVVKAGETIVIPA
EEHHHCCCCCCEEHEEHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCEEEECCCEEEEEE
FVDKYKVKGKAKFLKAYVP
HHCCCCCCCHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]