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The map label for this gene is deoD [H]

Identifier: 20808171

GI number: 20808171

Start: 1698215

End: 1698913

Strand: Reverse

Name: deoD [H]

Synonym: TTE1752

Alternate gene names: 20808171

Gene position: 1698913-1698215 (Counterclockwise)

Preceding gene: 20808172

Following gene: 20808170

Centisome position: 63.17

GC content: 42.06

Gene sequence:

>699_bases
ATGAGCATACATATTGGAGCAAAAGAAGGAGACATTGCCGAAACAGTACTGCTTCCGGGAGACCCATTGAGGGCTAAATA
TATAGCAGAAAATTTACTGGAAGATGCAAAGTGCTACAATGAAGTCAGAGGTATGTACGGCTTCACCGGATATTACAAGG
GGAAAAGAGTGTCAGTGCAAGGAACAGGAATGGGGGTGCCTTCTATATCCATTTATGTGAATGAACTTATAACAAGTTAC
GGCGTGAAAAACTTGATAAGAATAGGTACATGCGGTTCATTACAGCCAGACATAAAGATAAGAGATATTGTGATTGCTAT
GAGCGCCTCAACTGACTCTGCTATAAATAAAATACGTTTTAATGGAATGGATTACGCTCCTACGGCAAGTTTTAAGCTTT
TGAAAAAAGCCTATGACAAGGCTGTTGAAATGGGGATAGAGCCAAAAGTTGGAAATATACTTACTACAGATACTTTCTAC
CATGACGACCCAGAGAGCTGGAGGCTTTGGGCAAAATTTGGAGTGTTGGCTGTAGAAATGGAGACAGCGGGGCTTTACAC
TTTGGCTGCCAAGTATGGGGTTGATGCTCTTACTATACTTACTGTAAGCGACAGTTTGGTTACAGGTGAAGCGACCTCAG
CTGAGGAGAGGCAGAAAACTTTCATGGACATGGTTAAGATTGCTCTGGAGATTGCATAG

Upstream 100 bases:

>100_bases
TTGTTAAAGGGGTTTTTGTCGTTTTTTACTTTTTGTTTGATTTAAAAACGTTTTTTTGTTAATATTATATTTAGCGAAAC
TCATAGAGAGGAGGAAATAC

Downstream 100 bases:

>100_bases
TAAAGTGGCATTTGAAAATGCCACTTTACTATTATCTATTTAGAAAGGAGAGATATTTTATGGAACCTCTTAAGTTTAAG
CCAATATTTATGGAGAGAAT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSIHIGAKEGDIAETVLLPGDPLRAKYIAENLLEDAKCYNEVRGMYGFTGYYKGKRVSVQGTGMGVPSISIYVNELITSY
GVKNLIRIGTCGSLQPDIKIRDIVIAMSASTDSAINKIRFNGMDYAPTASFKLLKKAYDKAVEMGIEPKVGNILTTDTFY
HDDPESWRLWAKFGVLAVEMETAGLYTLAAKYGVDALTILTVSDSLVTGEATSAEERQKTFMDMVKIALEIA

Sequences:

>Translated_232_residues
MSIHIGAKEGDIAETVLLPGDPLRAKYIAENLLEDAKCYNEVRGMYGFTGYYKGKRVSVQGTGMGVPSISIYVNELITSY
GVKNLIRIGTCGSLQPDIKIRDIVIAMSASTDSAINKIRFNGMDYAPTASFKLLKKAYDKAVEMGIEPKVGNILTTDTFY
HDDPESWRLWAKFGVLAVEMETAGLYTLAAKYGVDALTILTVSDSLVTGEATSAEERQKTFMDMVKIALEIA
>Mature_231_residues
SIHIGAKEGDIAETVLLPGDPLRAKYIAENLLEDAKCYNEVRGMYGFTGYYKGKRVSVQGTGMGVPSISIYVNELITSYG
VKNLIRIGTCGSLQPDIKIRDIVIAMSASTDSAINKIRFNGMDYAPTASFKLLKKAYDKAVEMGIEPKVGNILTTDTFYH
DDPESWRLWAKFGVLAVEMETAGLYTLAAKYGVDALTILTVSDSLVTGEATSAEERQKTFMDMVKIALEIA

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=227, Percent_Identity=56.3876651982379, Blast_Score=277, Evalue=5e-76,
Organism=Escherichia coli, GI1790265, Length=247, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25375; Mature: 25243

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHIGAKEGDIAETVLLPGDPLRAKYIAENLLEDAKCYNEVRGMYGFTGYYKGKRVSVQ
CEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEE
GTGMGVPSISIYVNELITSYGVKNLIRIGTCGSLQPDIKIRDIVIAMSASTDSAINKIRF
ECCCCCCHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHEEE
NGMDYAPTASFKLLKKAYDKAVEMGIEPKVGNILTTDTFYHDDPESWRLWAKFGVLAVEM
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCHHHEEEEECCEEEEEE
ETAGLYTLAAKYGVDALTILTVSDSLVTGEATSAEERQKTFMDMVKIALEIA
ECCCEEEEHHHHCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIHIGAKEGDIAETVLLPGDPLRAKYIAENLLEDAKCYNEVRGMYGFTGYYKGKRVSVQ
EEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEE
GTGMGVPSISIYVNELITSYGVKNLIRIGTCGSLQPDIKIRDIVIAMSASTDSAINKIRF
ECCCCCCHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHEEE
NGMDYAPTASFKLLKKAYDKAVEMGIEPKVGNILTTDTFYHDDPESWRLWAKFGVLAVEM
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCHHHEEEEECCEEEEEE
ETAGLYTLAAKYGVDALTILTVSDSLVTGEATSAEERQKTFMDMVKIALEIA
ECCCEEEEHHHHCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA