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The map label for this gene is Lap4 [H]

Identifier: 20808106

GI number: 20808106

Start: 1628614

End: 1630017

Strand: Reverse

Name: Lap4 [H]

Synonym: TTE1680

Alternate gene names: 20808106

Gene position: 1630017-1628614 (Counterclockwise)

Preceding gene: 20808107

Following gene: 20808103

Centisome position: 60.61

GC content: 41.03

Gene sequence:

>1404_bases
TTGGAAGAAAAAGATCTGAAGGAAATTGAAAAGAGACTGGGGTATAAAAATGTGGATGCATGGACTAAAATTTCCAGTGA
GGAGAGGGAAAAAGTATTTGAGTTTGCAGAAGGCTATAAAGAATTTATGGCAGAGTGTAAAACTGAAAGGGAAACAGCGG
AGAAGATAATTAAAATTGCGGAAGAACACGGCTTTATTGACATTGAAAAAGCTACAAATTTGAAACCAGGCAGCAAAGTG
TACTACAACAACAAAGGGAAATCAGTAGTCTTAGCTGTAATTGGGAAAGAGTCCATGCAAAAGGGCATTAAAGCCGTAGC
CTCCCACATAGATTCTCCTCGAATAGATTTAAAGCCCAATCCTCTGTATGAAGAAGGCGGATTAGCGCTTTTTAAAACCC
ACTACTACGGAGGCATTAAGAAATATCAATGGGTTACAATACCTCTGGCGCTTCACGGCGTAATTGTAAAGTCAAACGGA
GAAAAGATAAATATAGTGGTGGGGGAAGACGAGAACGACCCTGTACTTTACATAACTGATTTACTGCCCCATTTAGGGAA
AGACCAAATGGAAAAGAAAGCGTCGGAAGTGGTGACAGGGGAAGCTTTAAATGCAGTAGTGGGAAGTATACCGCTGTCTG
AGGAAGTAAGTGTAAAACCGAGTATACTCAAATATTTAAATGAGAAGTACGGCATAGTAGAAGAAGATTTATTAAGCGCT
GAATTAGAACTAGTTCCCGCTTACAAACCAAGAGATGTAGGTTTTGACAGAAGTATGATTGCAGCTTACGGGCAGGATGA
CAGAGTCTCTGCTTACACTTCCCTGAAAGCTATCCTGGAGATAGGAGTTCCTGAAAGGACTGCTGTTGCTATATTTGCAG
ATAAAGAAGAAGTAGGAAGCATGGGAAATACAGGTTTGCAGTCAAGGTTTTTTGAAAACGCCATTGCAGAAATCCTTGAA
AAATATGAGGGCAGTACTGATATAAAACTAAGGAGACTTATGGCAAACTCTGAAATGCTCTCTGCAGATGTAAATGCTGC
TTTTGACCCGACGTATGCTGAAGTGAGTGAAAAACAAAACACAGCTTATTTTGGTAAGGGTGTATGCATAACAAAATACA
CTGGGGTGAGAGGAAAAGCTGGATCCAATGATGCAAATGCAGAGTTTGTGGGGAAAGTTAGAAGGCTTTTCAATGAAAAT
GGAGTAATCTGGCAGATGGAAGAACTTGGGAAGGTTGACATGGGAGGCGGCGGCACTGTAGCTCAATATGCAGCTAATTA
CGGGATGGAAGTGTTGGACTGCGGCGTGGCTCTTTTGAGCATGCACGCGCCTTATGAATTGTCTTCCAAAGTGGATGTGT
ACATGGCTTACAAAGCCTATAAAGTTTTCATGGAAAAAGATTAA

Upstream 100 bases:

>100_bases
AGAGTTAATCCTTTACAAGGCTAAATTTGACTTTTATTCAAAAAGGGAATAATATTATAGATGGATGTTTCAATATTAAA
AGCAGCGGGGGGTAATGTAA

Downstream 100 bases:

>100_bases
TCCGGGAAGTTCCCGGATTAATCTTTTATAAAAAGTTCCACTACTATTATTCCATTTCCTTGTTTATTTTTTACTATTCC
GACTCCAATTTTATTGTAAT

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEEKDLKEIEKRLGYKNVDAWTKISSEEREKVFEFAEGYKEFMAECKTERETAEKIIKIAEEHGFIDIEKATNLKPGSKV
YYNNKGKSVVLAVIGKESMQKGIKAVASHIDSPRIDLKPNPLYEEGGLALFKTHYYGGIKKYQWVTIPLALHGVIVKSNG
EKINIVVGEDENDPVLYITDLLPHLGKDQMEKKASEVVTGEALNAVVGSIPLSEEVSVKPSILKYLNEKYGIVEEDLLSA
ELELVPAYKPRDVGFDRSMIAAYGQDDRVSAYTSLKAILEIGVPERTAVAIFADKEEVGSMGNTGLQSRFFENAIAEILE
KYEGSTDIKLRRLMANSEMLSADVNAAFDPTYAEVSEKQNTAYFGKGVCITKYTGVRGKAGSNDANAEFVGKVRRLFNEN
GVIWQMEELGKVDMGGGGTVAQYAANYGMEVLDCGVALLSMHAPYELSSKVDVYMAYKAYKVFMEKD

Sequences:

>Translated_467_residues
MEEKDLKEIEKRLGYKNVDAWTKISSEEREKVFEFAEGYKEFMAECKTERETAEKIIKIAEEHGFIDIEKATNLKPGSKV
YYNNKGKSVVLAVIGKESMQKGIKAVASHIDSPRIDLKPNPLYEEGGLALFKTHYYGGIKKYQWVTIPLALHGVIVKSNG
EKINIVVGEDENDPVLYITDLLPHLGKDQMEKKASEVVTGEALNAVVGSIPLSEEVSVKPSILKYLNEKYGIVEEDLLSA
ELELVPAYKPRDVGFDRSMIAAYGQDDRVSAYTSLKAILEIGVPERTAVAIFADKEEVGSMGNTGLQSRFFENAIAEILE
KYEGSTDIKLRRLMANSEMLSADVNAAFDPTYAEVSEKQNTAYFGKGVCITKYTGVRGKAGSNDANAEFVGKVRRLFNEN
GVIWQMEELGKVDMGGGGTVAQYAANYGMEVLDCGVALLSMHAPYELSSKVDVYMAYKAYKVFMEKD
>Mature_467_residues
MEEKDLKEIEKRLGYKNVDAWTKISSEEREKVFEFAEGYKEFMAECKTERETAEKIIKIAEEHGFIDIEKATNLKPGSKV
YYNNKGKSVVLAVIGKESMQKGIKAVASHIDSPRIDLKPNPLYEEGGLALFKTHYYGGIKKYQWVTIPLALHGVIVKSNG
EKINIVVGEDENDPVLYITDLLPHLGKDQMEKKASEVVTGEALNAVVGSIPLSEEVSVKPSILKYLNEKYGIVEEDLLSA
ELELVPAYKPRDVGFDRSMIAAYGQDDRVSAYTSLKAILEIGVPERTAVAIFADKEEVGSMGNTGLQSRFFENAIAEILE
KYEGSTDIKLRRLMANSEMLSADVNAAFDPTYAEVSEKQNTAYFGKGVCITKYTGVRGKAGSNDANAEFVGKVRRLFNEN
GVIWQMEELGKVDMGGGGTVAQYAANYGMEVLDCGVALLSMHAPYELSSKVDVYMAYKAYKVFMEKD

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=421, Percent_Identity=25.41567695962, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17552916, Length=469, Percent_Identity=24.3070362473348, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322746, Length=458, Percent_Identity=22.2707423580786, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6321905, Length=473, Percent_Identity=24.1014799154334, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51793; Mature: 51793

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKDLKEIEKRLGYKNVDAWTKISSEEREKVFEFAEGYKEFMAECKTERETAEKIIKIA
CCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEHGFIDIEKATNLKPGSKVYYNNKGKSVVLAVIGKESMQKGIKAVASHIDSPRIDLKPN
HHCCCEEEHHCCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
PLYEEGGLALFKTHYYGGIKKYQWVTIPLALHGVIVKSNGEKINIVVGEDENDPVLYITD
CCCCCCCEEEEEEHHCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEEECCCCCCEEEHHH
LLPHLGKDQMEKKASEVVTGEALNAVVGSIPLSEEVSVKPSILKYLNEKYGIVEEDLLSA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
ELELVPAYKPRDVGFDRSMIAAYGQDDRVSAYTSLKAILEIGVPERTAVAIFADKEEVGS
HHEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECHHHHCC
MGNTGLQSRFFENAIAEILEKYEGSTDIKLRRLMANSEMLSADVNAAFDPTYAEVSEKQN
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCCCCCCCHHHHHHCCCC
TAYFGKGVCITKYTGVRGKAGSNDANAEFVGKVRRLFNENGVIWQMEELGKVDMGGGGTV
CEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHCCCEECCCCCHH
AQYAANYGMEVLDCGVALLSMHAPYELSSKVDVYMAYKAYKVFMEKD
HHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEEEECC
>Mature Secondary Structure
MEEKDLKEIEKRLGYKNVDAWTKISSEEREKVFEFAEGYKEFMAECKTERETAEKIIKIA
CCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEHGFIDIEKATNLKPGSKVYYNNKGKSVVLAVIGKESMQKGIKAVASHIDSPRIDLKPN
HHCCCEEEHHCCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
PLYEEGGLALFKTHYYGGIKKYQWVTIPLALHGVIVKSNGEKINIVVGEDENDPVLYITD
CCCCCCCEEEEEEHHCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEEECCCCCCEEEHHH
LLPHLGKDQMEKKASEVVTGEALNAVVGSIPLSEEVSVKPSILKYLNEKYGIVEEDLLSA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
ELELVPAYKPRDVGFDRSMIAAYGQDDRVSAYTSLKAILEIGVPERTAVAIFADKEEVGS
HHEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECHHHHCC
MGNTGLQSRFFENAIAEILEKYEGSTDIKLRRLMANSEMLSADVNAAFDPTYAEVSEKQN
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCCCCCCCHHHHHHCCCC
TAYFGKGVCITKYTGVRGKAGSNDANAEFVGKVRRLFNENGVIWQMEELGKVDMGGGGTV
CEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHCCCEECCCCCHH
AQYAANYGMEVLDCGVALLSMHAPYELSSKVDVYMAYKAYKVFMEKD
HHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]