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The map label for this gene is FtsI3 [H]

Identifier: 20808078

GI number: 20808078

Start: 1602039

End: 1604075

Strand: Reverse

Name: FtsI3 [H]

Synonym: TTE1651

Alternate gene names: 20808078

Gene position: 1604075-1602039 (Counterclockwise)

Preceding gene: 20808079

Following gene: 20808077

Centisome position: 59.64

GC content: 41.73

Gene sequence:

>2037_bases
TTGCTGTTTCTGTCTTTTGCTGTTGTGTTTGGACTTATGATGAGACTTTTCTTCATACAAGTGGTAAAAGGCGAAGAATA
TCAAAAGATGGCTTTGCCTCAATGGACGTTGGATGTGTCTTTAAGTGGCAAAAGAGGGTATATATTTGATAGAAACGGAA
AGGTTTTGGCTGAAAATGCAAGTGTGAGCAAAATTAGCGTGATTCCAAAAGAAATTCCAGATTCTAAAAGGCAGGTAGTG
GCAGAAACTTTGGCCAGTATCCTTGGCCTTGATAGACAAAAAGTTTTGGAAAGAATTTCTAATAAAAACTTGCAAGAGGT
ATTGATTGCCAAGCAGGTAGATGAGGAAAAGGCGAAAGCCATATTGAGACTTAATATAGATGGGGTAATAGTTTCTGAAG
ACATGAAGAGATTTTATCCAGAAGGCACACTTGCCTGCCATGTTTTAGGCTTTACAGGAATTGATAATCAGGGATTGGAC
GGAATAGAGCTTGTATTTGATAATTTTTTGAGAGGAATACCTGGAAAGTCTACCACTCCCATGGATGCCATAGGGCGAAA
GATAGACACAGGAGAGGAAGAGTATTTTGAACCTCTTCCAGGATATAATGTAGTTCTCACTATTGATGAGACAATACAGC
ATTTTGCTGAGAAGGCTTTGAATCAGGCTATGGTACATTCTAAGCCTTCAAAAGGTGCAGTGGCCATTGTAATGGACCCC
AAAACAGGCGAAATACTGGCTTTGGCCAATAGGCCTAATTTCGATCCCAATGATCCCTTTGAAGGTCCTGAAGAAGAATG
GTATAGGCGGTGGAGGAATAAGGCAATTTCTGACTCCTATGAACCGGGTTCTGTCTTTAAAACTATAACTGCTTCTGCTG
CACTAGAGGAAAAGGTTGTAAGTTTACATGAACAGTTCTACTGCCCCGGCTATACGACTGTTGCAGGGCACAGGATTAAT
TGCTGGGCAACACATGGTAGCGAGGATTTTGTAAAAGGAGTGCAGAATTCTTGTAACGTGGTCTTTGTGACTGTAGGGCA
GAGGCTGGGAGTTGAAAAACTATATAAATACATAAGAGATTTTGGATTTGGAAAGACTACAGGTATTCTTCTTCCTGGAG
AAGCTCCCGGGCTTGTATTGTCGGAAGAAAGAGTTGGACCTGTAGAACTGGCAACAAATTCTTTTGGGCAGGGCATTGCA
GTTACTCCCCTTCAGATGATTACAGCAGTAGCTGCTATAGCTAATGGAGGCAAATTGATGCAACCGCAGATAGTGAAGGC
AATCGTCGATTCAAAGGGGAAAGTGGTAAAAGAGTTTAAGCCGAAGATTGTAAGGCGTGTAATTTCAAAAGAAACTTCTG
CTACAATGCGGGAAATACTAAAAAGTGTGGTGGCAGAAGGTACAGGCAAAGCAGGTTATATTGAAGGCTTTGACGTGGCG
GGGAAGACAGGAACCACAGAGAAGTACATGCCGGGGAAATATGTAGCTTCTTTTGTAGGATTTGCGCCGGCAGATGACCC
AAAAGTTATTGTGCTTGTCGTCATAGATGAGCCTAACAACCCAGAGACCCACTTTGGAAGTCAGCTGGCTGCACCTGTTG
TGAAGAGCATTTTGGACGATACTTTAAAATATCTGGAAGTCCAGCCCAGAGGGGTAAAAAAGCCCGAGACGGTAATGGTG
CCAGATGTGAGGAACATGAAATTGTATGAAGCAGAAAGAATTATACTTGAAAATAAGCTTGATTTTATTTTACAGGGAAA
TGGAGATACTGTATTTGACCAGGTTCCAAAGCCTGGAGCTTTGGTCAATGAGAATACTAAAATTATACTGTATTTAAATG
GAGTTTCTACAGAGGAAGTAGTGGTACCTGATTTGAAAGGGAAAAGTGTTAAAGAAGCGACAGAGATTTTGAACAGCCTG
GGCTTAAGGATAAAAATAAAAGGTACAGGATTTGCAGTGGACCAGAGTCCTAAAGAGGGGACGCTTGTTAAAAGGGGAGA
AGTTGTGGAAGTTGAGTTCAGGCCGAAGGAAAATTGA

Upstream 100 bases:

>100_bases
TAAAAAGGACAGTTTCTTCATGAGGTTATTGGGGGTGTTCAATAGATAGGGGGGATTTTAGATACATCCAACGGTTTCTA
CGAAAAAGCGAATTCTTTTT

Downstream 100 bases:

>100_bases
CATAGTGTAAAATTATCGTAGGATTTTTTGAGTGAAAAAAACAAGAGACAACCCCTGTGATAAAATAGAACTTGGAAACA
AAACATCACAGAAAGGGGTG

Product: cell division protein FtsI/penicillin-binding protein 2

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MLFLSFAVVFGLMMRLFFIQVVKGEEYQKMALPQWTLDVSLSGKRGYIFDRNGKVLAENASVSKISVIPKEIPDSKRQVV
AETLASILGLDRQKVLERISNKNLQEVLIAKQVDEEKAKAILRLNIDGVIVSEDMKRFYPEGTLACHVLGFTGIDNQGLD
GIELVFDNFLRGIPGKSTTPMDAIGRKIDTGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDP
KTGEILALANRPNFDPNDPFEGPEEEWYRRWRNKAISDSYEPGSVFKTITASAALEEKVVSLHEQFYCPGYTTVAGHRIN
CWATHGSEDFVKGVQNSCNVVFVTVGQRLGVEKLYKYIRDFGFGKTTGILLPGEAPGLVLSEERVGPVELATNSFGQGIA
VTPLQMITAVAAIANGGKLMQPQIVKAIVDSKGKVVKEFKPKIVRRVISKETSATMREILKSVVAEGTGKAGYIEGFDVA
GKTGTTEKYMPGKYVASFVGFAPADDPKVIVLVVIDEPNNPETHFGSQLAAPVVKSILDDTLKYLEVQPRGVKKPETVMV
PDVRNMKLYEAERIILENKLDFILQGNGDTVFDQVPKPGALVNENTKIILYLNGVSTEEVVVPDLKGKSVKEATEILNSL
GLRIKIKGTGFAVDQSPKEGTLVKRGEVVEVEFRPKEN

Sequences:

>Translated_678_residues
MLFLSFAVVFGLMMRLFFIQVVKGEEYQKMALPQWTLDVSLSGKRGYIFDRNGKVLAENASVSKISVIPKEIPDSKRQVV
AETLASILGLDRQKVLERISNKNLQEVLIAKQVDEEKAKAILRLNIDGVIVSEDMKRFYPEGTLACHVLGFTGIDNQGLD
GIELVFDNFLRGIPGKSTTPMDAIGRKIDTGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDP
KTGEILALANRPNFDPNDPFEGPEEEWYRRWRNKAISDSYEPGSVFKTITASAALEEKVVSLHEQFYCPGYTTVAGHRIN
CWATHGSEDFVKGVQNSCNVVFVTVGQRLGVEKLYKYIRDFGFGKTTGILLPGEAPGLVLSEERVGPVELATNSFGQGIA
VTPLQMITAVAAIANGGKLMQPQIVKAIVDSKGKVVKEFKPKIVRRVISKETSATMREILKSVVAEGTGKAGYIEGFDVA
GKTGTTEKYMPGKYVASFVGFAPADDPKVIVLVVIDEPNNPETHFGSQLAAPVVKSILDDTLKYLEVQPRGVKKPETVMV
PDVRNMKLYEAERIILENKLDFILQGNGDTVFDQVPKPGALVNENTKIILYLNGVSTEEVVVPDLKGKSVKEATEILNSL
GLRIKIKGTGFAVDQSPKEGTLVKRGEVVEVEFRPKEN
>Mature_678_residues
MLFLSFAVVFGLMMRLFFIQVVKGEEYQKMALPQWTLDVSLSGKRGYIFDRNGKVLAENASVSKISVIPKEIPDSKRQVV
AETLASILGLDRQKVLERISNKNLQEVLIAKQVDEEKAKAILRLNIDGVIVSEDMKRFYPEGTLACHVLGFTGIDNQGLD
GIELVFDNFLRGIPGKSTTPMDAIGRKIDTGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDP
KTGEILALANRPNFDPNDPFEGPEEEWYRRWRNKAISDSYEPGSVFKTITASAALEEKVVSLHEQFYCPGYTTVAGHRIN
CWATHGSEDFVKGVQNSCNVVFVTVGQRLGVEKLYKYIRDFGFGKTTGILLPGEAPGLVLSEERVGPVELATNSFGQGIA
VTPLQMITAVAAIANGGKLMQPQIVKAIVDSKGKVVKEFKPKIVRRVISKETSATMREILKSVVAEGTGKAGYIEGFDVA
GKTGTTEKYMPGKYVASFVGFAPADDPKVIVLVVIDEPNNPETHFGSQLAAPVVKSILDDTLKYLEVQPRGVKKPETVMV
PDVRNMKLYEAERIILENKLDFILQGNGDTVFDQVPKPGALVNENTKIILYLNGVSTEEVVVPDLKGKSVKEATEILNSL
GLRIKIKGTGFAVDQSPKEGTLVKRGEVVEVEFRPKEN

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=558, Percent_Identity=31.3620071684588, Blast_Score=245, Evalue=9e-66,
Organism=Escherichia coli, GI1786854, Length=587, Percent_Identity=24.8722316865417, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 74554; Mature: 74554

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLSFAVVFGLMMRLFFIQVVKGEEYQKMALPQWTLDVSLSGKRGYIFDRNGKVLAENA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCCEEEECCCCEEECCC
SVSKISVIPKEIPDSKRQVVAETLASILGLDRQKVLERISNKNLQEVLIAKQVDEEKAKA
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCHHHCCE
ILRLNIDGVIVSEDMKRFYPEGTLACHVLGFTGIDNQGLDGIELVFDNFLRGIPGKSTTP
EEEEECCCEEECCHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCC
MDAIGRKIDTGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDP
HHHHCCCCCCCCHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
KTGEILALANRPNFDPNDPFEGPEEEWYRRWRNKAISDSYEPGSVFKTITASAALEEKVV
CCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SLHEQFYCPGYTTVAGHRINCWATHGSEDFVKGVQNSCNVVFVTVGQRLGVEKLYKYIRD
HHHHHHCCCCCCEECCCEEEEEEECCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
FGFGKTTGILLPGEAPGLVLSEERVGPVELATNSFGQGIAVTPLQMITAVAAIANGGKLM
CCCCCCCCEEECCCCCCEEEECCCCCCEEEECCCCCCCEEECHHHHHHHHHHHHCCCCCC
QPQIVKAIVDSKGKVVKEFKPKIVRRVISKETSATMREILKSVVAEGTGKAGYIEGFDVA
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEECEECC
GKTGTTEKYMPGKYVASFVGFAPADDPKVIVLVVIDEPNNPETHFGSQLAAPVVKSILDD
CCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHCCHHHHHHHHHHHHHH
TLKYLEVQPRGVKKPETVMVPDVRNMKLYEAERIILENKLDFILQGNGDTVFDQVPKPGA
HHHHEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCC
LVNENTKIILYLNGVSTEEVVVPDLKGKSVKEATEILNSLGLRIKIKGTGFAVDQSPKEG
EECCCCEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEEEECCEEEECCCCCCC
TLVKRGEVVEVEFRPKEN
CEEECCCEEEEEECCCCC
>Mature Secondary Structure
MLFLSFAVVFGLMMRLFFIQVVKGEEYQKMALPQWTLDVSLSGKRGYIFDRNGKVLAENA
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCCEEEECCCCEEECCC
SVSKISVIPKEIPDSKRQVVAETLASILGLDRQKVLERISNKNLQEVLIAKQVDEEKAKA
CCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCHHHCCE
ILRLNIDGVIVSEDMKRFYPEGTLACHVLGFTGIDNQGLDGIELVFDNFLRGIPGKSTTP
EEEEECCCEEECCHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCC
MDAIGRKIDTGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDP
HHHHCCCCCCCCHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
KTGEILALANRPNFDPNDPFEGPEEEWYRRWRNKAISDSYEPGSVFKTITASAALEEKVV
CCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SLHEQFYCPGYTTVAGHRINCWATHGSEDFVKGVQNSCNVVFVTVGQRLGVEKLYKYIRD
HHHHHHCCCCCCEECCCEEEEEEECCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
FGFGKTTGILLPGEAPGLVLSEERVGPVELATNSFGQGIAVTPLQMITAVAAIANGGKLM
CCCCCCCCEEECCCCCCEEEECCCCCCEEEECCCCCCCEEECHHHHHHHHHHHHCCCCCC
QPQIVKAIVDSKGKVVKEFKPKIVRRVISKETSATMREILKSVVAEGTGKAGYIEGFDVA
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEECEECC
GKTGTTEKYMPGKYVASFVGFAPADDPKVIVLVVIDEPNNPETHFGSQLAAPVVKSILDD
CCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHCCHHHHHHHHHHHHHH
TLKYLEVQPRGVKKPETVMVPDVRNMKLYEAERIILENKLDFILQGNGDTVFDQVPKPGA
HHHHEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCC
LVNENTKIILYLNGVSTEEVVVPDLKGKSVKEATEILNSLGLRIKIKGTGFAVDQSPKEG
EECCCCEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEEEECCEEEECCCCCCC
TLVKRGEVVEVEFRPKEN
CEEECCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]