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The map label for this gene is mraY

Identifier: 20808075

GI number: 20808075

Start: 1597936

End: 1598886

Strand: Reverse

Name: mraY

Synonym: TTE1648

Alternate gene names: 20808075

Gene position: 1598886-1597936 (Counterclockwise)

Preceding gene: 20808076

Following gene: 20808074

Centisome position: 59.45

GC content: 37.33

Gene sequence:

>951_bases
ATGATACAAAAGATAATATTTGCGACTTTATTGTCTTTTACTGTAGCTATTATATCTGGGAGATTTTTTATTCCATACTT
AAGAAAGCTAAAATTTGGTCAAAAAGTAAGAGAAGATGGACCTAAAACTCACTTGAAAAAGTCTGGCACTCCTACAATGG
GAGGAATTATATTTGTAGTTGCTACTTTTTTGACATCTCTGATTTTCTCTCCGTGGAATAAATATCTTTTTATACTGCTA
GCAGGATTTTTAGGATATGGACTTATAGGTTTTGCAGACGACTTTTTAAAAGTGTATTTTAAAAGGTCTTTAGGGCTTCG
CGCTAGAGAAAAACTGCTGGCACAGTTTTTGCTGGCCATTGTAATTTCTTGGTTTATAAAGAGCAATGTGGGCACAGAGA
TAATCGTCCCATTTTTTAAGAGGTCTGTTGATTTAGCGAATTTTTATATTCCTTTTGCTGTGTTTATAATTGTTGGAACT
GTGAACAGCGTCAACCTTACGGATGGGCTGGATGGATTGGCAGCAGGAGTATCCACTATTGTCATGGCTTTTTTTGCAAT
GATTGCTCTGTTTTTAAACGATGTGACCTATGGAGTATTCAGCGCTTCTTTGACAGGAGGACTGCTTGGGTTTTTGAGGT
ACAATAAGCATCCCGCTGAAGTGTTTATGGGGGATACAGGTTCTCTTGCGATTGGGGGAGCGGTAGCGACTGTTGCGCTT
CTTACCAAACTTCCTTTGATATTGCCTGTTTTAGGGATAATTTATGTGGCTGAGGCTATTTCAGTTATTTTGCAGGTGTT
TTCTTTCAAGTTATTCGGAAAGAGGATTTTTAAAATGAGCCCTTTGCATCACCATTTTGAGCTTTCGGGTTGGAAAGAAG
AGAAAGTTGTATACAGCTTTTGGTTGGTTACATTGATTGCTTTATTTGTATCTTTTTACAGTCTGAGTTAA

Upstream 100 bases:

>100_bases
TCAGATCATAGGGGATAAAGTCATTCCTTTTGATGAAAGAGAGATAGTGAAGGAAATCTTAGCTGAAAGCGAAAAATAAG
ACAGGAGAGGATAAGGTAGG

Downstream 100 bases:

>100_bases
GGAGTGCAGTGTATGGAATTGAAAGAAAAAAGAGTATTTGTAGCAGGGTTAGGCGTAAGTGGTGTAGCACTCTGCCGTGT
GCTTGTAAATCTGGGAGCAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIQKIIFATLLSFTVAIISGRFFIPYLRKLKFGQKVREDGPKTHLKKSGTPTMGGIIFVVATFLTSLIFSPWNKYLFILL
AGFLGYGLIGFADDFLKVYFKRSLGLRAREKLLAQFLLAIVISWFIKSNVGTEIIVPFFKRSVDLANFYIPFAVFIIVGT
VNSVNLTDGLDGLAAGVSTIVMAFFAMIALFLNDVTYGVFSASLTGGLLGFLRYNKHPAEVFMGDTGSLAIGGAVATVAL
LTKLPLILPVLGIIYVAEAISVILQVFSFKLFGKRIFKMSPLHHHFELSGWKEEKVVYSFWLVTLIALFVSFYSLS

Sequences:

>Translated_316_residues
MIQKIIFATLLSFTVAIISGRFFIPYLRKLKFGQKVREDGPKTHLKKSGTPTMGGIIFVVATFLTSLIFSPWNKYLFILL
AGFLGYGLIGFADDFLKVYFKRSLGLRAREKLLAQFLLAIVISWFIKSNVGTEIIVPFFKRSVDLANFYIPFAVFIIVGT
VNSVNLTDGLDGLAAGVSTIVMAFFAMIALFLNDVTYGVFSASLTGGLLGFLRYNKHPAEVFMGDTGSLAIGGAVATVAL
LTKLPLILPVLGIIYVAEAISVILQVFSFKLFGKRIFKMSPLHHHFELSGWKEEKVVYSFWLVTLIALFVSFYSLS
>Mature_316_residues
MIQKIIFATLLSFTVAIISGRFFIPYLRKLKFGQKVREDGPKTHLKKSGTPTMGGIIFVVATFLTSLIFSPWNKYLFILL
AGFLGYGLIGFADDFLKVYFKRSLGLRAREKLLAQFLLAIVISWFIKSNVGTEIIVPFFKRSVDLANFYIPFAVFIIVGT
VNSVNLTDGLDGLAAGVSTIVMAFFAMIALFLNDVTYGVFSASLTGGLLGFLRYNKHPAEVFMGDTGSLAIGGAVATVAL
LTKLPLILPVLGIIYVAEAISVILQVFSFKLFGKRIFKMSPLHHHFELSGWKEEKVVYSFWLVTLIALFVSFYSLS

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=334, Percent_Identity=40.7185628742515, Blast_Score=238, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_THETN (Q8R9G3)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623246.1
- GeneID:   996202
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1648
- NMPDR:   fig|273068.3.peg.1630
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   TTEN273068:TTE1648-MONOMER
- BRENDA:   2.7.8.13
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 34994; Mature: 34994

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeb0d228)-; HASH(0xf2312a4)-; HASH(0xf258510)-; HASH(0xf25884c)-; HASH(0xf231448)-; HASH(0xd376a40)-; HASH(0xf257680)-; HASH(0xf252854)-; HASH(0xf258558)-; HASH(0xd376ad0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336