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The map label for this gene is FtsA2 [H]

Identifier: 20808067

GI number: 20808067

Start: 1589938

End: 1591164

Strand: Reverse

Name: FtsA2 [H]

Synonym: TTE1640

Alternate gene names: 20808067

Gene position: 1591164-1589938 (Counterclockwise)

Preceding gene: 20808068

Following gene: 20808066

Centisome position: 59.16

GC content: 39.28

Gene sequence:

>1227_bases
ATGGGAGATTTGATAGTAGGTTTGGACATTGGCACGTCTAAGGTATGCACAATCATTGGGGAAGGGGATAAGACGGGAGA
ACTTCATATAGTGGGCATAGGGTATTATCCTTCTACTGGTGTGAAAAAGGGCATTATAGTGGATATAGATGAAACTGCCT
ACTCAATCCAGAAATCTGTAGAACAGGCTGAAAGAATGGCTAATAGAAAAATTTCATCTGTGTACTTGAAAATATACGGT
GGACTTACTACTATATACAAGAATAATGGAGTAGTAGCAGTTTCAAGAGAAGACAGAGAAATAACAAGACAGGATGTGGA
GAGGGTATTGCAGGCTGCTAAGATAATAGCCCTTCCTTCGGATAAACAGATCATAGATGTGATTCCTTTGGAGTACATAG
TGGATGGATATGGGGAGATAAAAGACCCAGTTGGAATGTCAGGAATACGGTTGGAAGTAAACGCGGCTGTGGTGACAGGG
AGTGTCACTGCTATACAGAATATGGAAAAGTGTGTAAGAAAAGCAGGCTTGGAAATAGATGGCATTATCGTAGGGCCTCT
TGCTACTTCTGAAGCTGTTCTTTTAAAGGATGAAAAAGAATTGGGAGTTGCACTTATTGACGTTGGGGCAGGGGTTACAG
ATATATCTGTTTTTAAAAATGGCGGACTCATTTATTCTTCTATGATAGCGGTTGGGGGATGGCATATAACCAATGACCTT
TCGGTTGGATTAAAGATTTCCTTTGAAGAAGCCGAAAATATAAAGAAAAAATACGGCACTTTGGAAAAAGTGGATCCAGA
CAGATTAGAACCCATAAAAATTGCCAGTTTAGCAGGCAAGTCAAAGACTACCACCGATATAAATGAAATTGCTGACATAA
TAGAGGCAAGGGTGTCAGAACTCTTAACTCTTGTATATGAACGCTTAGAAGAGGCTGGGGTTTTAGAAGACATTGTGACT
AATGTAGTCATTACAGGAGGAGGTATTTCCTTTTTAAAAGGGAGTGTAGAGCTTGCTCAGAAAATATTTGACAGAAATGT
GAGAATTGGTTCCCCGCAAAACATTGGAGTGGCTACCCCTATTTACTCAGCAGGGGTTGGAGTGGTAAAATATGTATATA
ACAACAGGAGATTTATGTATCCGAGTACATCCACTGACAAAAAGGAAAAGAAAAATTCTCGGTTGTTAGATAAGTTAAAA
GAAATTTTTAGTGATTTTTGGGCGTAA

Upstream 100 bases:

>100_bases
TGTGTTTGGAAGCAGGCTTTTCTCAAACTTTGCCTACATAAGAAGGTATTTGATAGACAGGATGCGGCGAAGGTAGTGGG
CTTTTAAGGAGGATTTTCAA

Downstream 100 bases:

>100_bases
GAGGAGGGTTTTGTGTGATAGGATTGGAGACTGATGTACAACAGTTTGCTGCTATTAAGGTGATAGGAGTTGGCGGTGGC
GGAGGAAATGCTGTAAACCG

Product: ATPase of the HSP70 class involved in cell division

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MGDLIVGLDIGTSKVCTIIGEGDKTGELHIVGIGYYPSTGVKKGIIVDIDETAYSIQKSVEQAERMANRKISSVYLKIYG
GLTTIYKNNGVVAVSREDREITRQDVERVLQAAKIIALPSDKQIIDVIPLEYIVDGYGEIKDPVGMSGIRLEVNAAVVTG
SVTAIQNMEKCVRKAGLEIDGIIVGPLATSEAVLLKDEKELGVALIDVGAGVTDISVFKNGGLIYSSMIAVGGWHITNDL
SVGLKISFEEAENIKKKYGTLEKVDPDRLEPIKIASLAGKSKTTTDINEIADIIEARVSELLTLVYERLEEAGVLEDIVT
NVVITGGGISFLKGSVELAQKIFDRNVRIGSPQNIGVATPIYSAGVGVVKYVYNNRRFMYPSTSTDKKEKKNSRLLDKLK
EIFSDFWA

Sequences:

>Translated_408_residues
MGDLIVGLDIGTSKVCTIIGEGDKTGELHIVGIGYYPSTGVKKGIIVDIDETAYSIQKSVEQAERMANRKISSVYLKIYG
GLTTIYKNNGVVAVSREDREITRQDVERVLQAAKIIALPSDKQIIDVIPLEYIVDGYGEIKDPVGMSGIRLEVNAAVVTG
SVTAIQNMEKCVRKAGLEIDGIIVGPLATSEAVLLKDEKELGVALIDVGAGVTDISVFKNGGLIYSSMIAVGGWHITNDL
SVGLKISFEEAENIKKKYGTLEKVDPDRLEPIKIASLAGKSKTTTDINEIADIIEARVSELLTLVYERLEEAGVLEDIVT
NVVITGGGISFLKGSVELAQKIFDRNVRIGSPQNIGVATPIYSAGVGVVKYVYNNRRFMYPSTSTDKKEKKNSRLLDKLK
EIFSDFWA
>Mature_407_residues
GDLIVGLDIGTSKVCTIIGEGDKTGELHIVGIGYYPSTGVKKGIIVDIDETAYSIQKSVEQAERMANRKISSVYLKIYGG
LTTIYKNNGVVAVSREDREITRQDVERVLQAAKIIALPSDKQIIDVIPLEYIVDGYGEIKDPVGMSGIRLEVNAAVVTGS
VTAIQNMEKCVRKAGLEIDGIIVGPLATSEAVLLKDEKELGVALIDVGAGVTDISVFKNGGLIYSSMIAVGGWHITNDLS
VGLKISFEEAENIKKKYGTLEKVDPDRLEPIKIASLAGKSKTTTDINEIADIIEARVSELLTLVYERLEEAGVLEDIVTN
VVITGGGISFLKGSVELAQKIFDRNVRIGSPQNIGVATPIYSAGVGVVKYVYNNRRFMYPSTSTDKKEKKNSRLLDKLKE
IFSDFWA

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=380, Percent_Identity=35.2631578947368, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 44250; Mature: 44118

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00277 STAPH_STREP_TOXIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDLIVGLDIGTSKVCTIIGEGDKTGELHIVGIGYYPSTGVKKGIIVDIDETAYSIQKSV
CCCEEEEEECCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECHHHHHHHHHH
EQAERMANRKISSVYLKIYGGLTTIYKNNGVVAVSREDREITRQDVERVLQAAKIIALPS
HHHHHHHHCCHHHEEEEEECCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEECCC
DKQIIDVIPLEYIVDGYGEIKDPVGMSGIRLEVNAAVVTGSVTAIQNMEKCVRKAGLEID
CCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCC
GIIVGPLATSEAVLLKDEKELGVALIDVGAGVTDISVFKNGGLIYSSMIAVGGWHITNDL
CEEECCCCCCCEEEEECCHHCCEEEEECCCCCEEEEEEECCCEEEEHHHHHCCEEEECCE
SVGLKISFEEAENIKKKYGTLEKVDPDRLEPIKIASLAGKSKTTTDINEIADIIEARVSE
EEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LLTLVYERLEEAGVLEDIVTNVVITGGGISFLKGSVELAQKIFDRNVRIGSPQNIGVATP
HHHHHHHHHHHCCHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
IYSAGVGVVKYVYNNRRFMYPSTSTDKKEKKNSRLLDKLKEIFSDFWA
HHHCCHHHHHHEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDLIVGLDIGTSKVCTIIGEGDKTGELHIVGIGYYPSTGVKKGIIVDIDETAYSIQKSV
CCEEEEEECCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECHHHHHHHHHH
EQAERMANRKISSVYLKIYGGLTTIYKNNGVVAVSREDREITRQDVERVLQAAKIIALPS
HHHHHHHHCCHHHEEEEEECCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEECCC
DKQIIDVIPLEYIVDGYGEIKDPVGMSGIRLEVNAAVVTGSVTAIQNMEKCVRKAGLEID
CCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHCCCCCC
GIIVGPLATSEAVLLKDEKELGVALIDVGAGVTDISVFKNGGLIYSSMIAVGGWHITNDL
CEEECCCCCCCEEEEECCHHCCEEEEECCCCCEEEEEEECCCEEEEHHHHHCCEEEECCE
SVGLKISFEEAENIKKKYGTLEKVDPDRLEPIKIASLAGKSKTTTDINEIADIIEARVSE
EEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LLTLVYERLEEAGVLEDIVTNVVITGGGISFLKGSVELAQKIFDRNVRIGSPQNIGVATP
HHHHHHHHHHHCCHHHHHHHCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
IYSAGVGVVKYVYNNRRFMYPSTSTDKKEKKNSRLLDKLKEIFSDFWA
HHHCCHHHHHHEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3139638; 9384377; 1569582; 1624452 [H]