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The map label for this gene is AraD [H]

Identifier: 20808021

GI number: 20808021

Start: 1548769

End: 1549416

Strand: Reverse

Name: AraD [H]

Synonym: TTE1592

Alternate gene names: 20808021

Gene position: 1549416-1548769 (Counterclockwise)

Preceding gene: 20808022

Following gene: 20808020

Centisome position: 57.61

GC content: 38.73

Gene sequence:

>648_bases
GTGCTTTTAAAATATGAGAGAGAACAAATAGTAGAGTACGGCAAAAAGCTCATAGATACAAATCTCACCAGAGGTACAGG
GGGAAATTTAAGTGTTTATGACTATAAAAGTGGACTTATGGCTATAACTCCTTCGGGAATGGACTATTATGAATTAAAAG
CTGAAGACATATTGGTGATGGATTTAGAGGGAAAAGTTGTAGAAGGGACAAAGGTTCCTTCTACTGAGTACGAGATGCAC
AGGATTTTTTATGTAAGAAGAGATGACATAAAAGCAATTATTCACACTCATCCTGTCTATACTACTACTCTAGCTTGTCT
TCACTGGGACCTGCCCCCTGTTCATTACCTAATAGCTTTGGCAGGACCTGATGTAAAATGCGCTAAATACGCTACTTTTG
GTACTAAGGAACTTGCTGAGAACGCTTTTGAGGCAATGAAAGGCAGAAAAGCTGTTTTGCTAGCTAATCACGGGCTTCTA
GTTGGTGCTGAAGACCTTCCGAATGCCTTCAATATAAGTATACAGATCGAGTATGTAGCAGAACTTTACTATAGAGCAAA
ATCTATAGGCGAACCTGTGCTTTTATCTTCTGAAGAGATGGAGCTTATGATGGAGAAGTTTAAAACTTATGGGCAGGTAA
GAAAATAA

Upstream 100 bases:

>100_bases
GGCTCAAAATTTGATAAGAGGAGAAATCAGTTGACAGCCCCTTTCTCTTGTTATATGATGGATTTAGTGGGAATATTCAT
ACAAAAACGGGGTGAAAAAC

Downstream 100 bases:

>100_bases
AAAATTTAAAAGGAGTGAAAAAGTGAAAGCCCTTTATTTTGACGGAAAGCTTAAGCTAAAAGACCTTCCAAAGCCTGAAA
TAGAAGAAGGAGAATCGTTG

Product: L-fuculose phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLLKYEREQIVEYGKKLIDTNLTRGTGGNLSVYDYKSGLMAITPSGMDYYELKAEDILVMDLEGKVVEGTKVPSTEYEMH
RIFYVRRDDIKAIIHTHPVYTTTLACLHWDLPPVHYLIALAGPDVKCAKYATFGTKELAENAFEAMKGRKAVLLANHGLL
VGAEDLPNAFNISIQIEYVAELYYRAKSIGEPVLLSSEEMELMMEKFKTYGQVRK

Sequences:

>Translated_215_residues
MLLKYEREQIVEYGKKLIDTNLTRGTGGNLSVYDYKSGLMAITPSGMDYYELKAEDILVMDLEGKVVEGTKVPSTEYEMH
RIFYVRRDDIKAIIHTHPVYTTTLACLHWDLPPVHYLIALAGPDVKCAKYATFGTKELAENAFEAMKGRKAVLLANHGLL
VGAEDLPNAFNISIQIEYVAELYYRAKSIGEPVLLSSEEMELMMEKFKTYGQVRK
>Mature_215_residues
MLLKYEREQIVEYGKKLIDTNLTRGTGGNLSVYDYKSGLMAITPSGMDYYELKAEDILVMDLEGKVVEGTKVPSTEYEMH
RIFYVRRDDIKAIIHTHPVYTTTLACLHWDLPPVHYLIALAGPDVKCAKYATFGTKELAENAFEAMKGRKAVLLANHGLL
VGAEDLPNAFNISIQIEYVAELYYRAKSIGEPVLLSSEEMELMMEKFKTYGQVRK

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=205, Percent_Identity=41.4634146341463, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1790642, Length=202, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786247, Length=112, Percent_Identity=37.5, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789094, Length=184, Percent_Identity=28.804347826087, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790008, Length=180, Percent_Identity=29.4444444444444, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 24355; Mature: 24355

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKYEREQIVEYGKKLIDTNLTRGTGGNLSVYDYKSGLMAITPSGMDYYELKAEDILVM
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCCCEEEECCCCEEEE
DLEGKVVEGTKVPSTEYEMHRIFYVRRDDIKAIIHTHPVYTTTLACLHWDLPPVHYLIAL
ECCCEEEECCCCCCCCCEEEEEEEEEECCEEEEEECCCHHHHEEEEHCCCCCHHHEEEEE
AGPDVKCAKYATFGTKELAENAFEAMKGRKAVLLANHGLLVGAEDLPNAFNISIQIEYVA
CCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCEEEEEEEEHHHH
ELYYRAKSIGEPVLLSSEEMELMMEKFKTYGQVRK
HHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLKYEREQIVEYGKKLIDTNLTRGTGGNLSVYDYKSGLMAITPSGMDYYELKAEDILVM
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCCCEEEECCCCEEEE
DLEGKVVEGTKVPSTEYEMHRIFYVRRDDIKAIIHTHPVYTTTLACLHWDLPPVHYLIAL
ECCCEEEECCCCCCCCCEEEEEEEEEECCEEEEEECCCHHHHEEEEHCCCCCHHHEEEEE
AGPDVKCAKYATFGTKELAENAFEAMKGRKAVLLANHGLLVGAEDLPNAFNISIQIEYVA
CCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCEEEEEEEEHHHH
ELYYRAKSIGEPVLLSSEEMELMMEKFKTYGQVRK
HHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]