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The map label for this gene is PabA [H]

Identifier: 20808011

GI number: 20808011

Start: 1538653

End: 1539222

Strand: Reverse

Name: PabA [H]

Synonym: TTE1582

Alternate gene names: 20808011

Gene position: 1539222-1538653 (Counterclockwise)

Preceding gene: 20808012

Following gene: 20808010

Centisome position: 57.23

GC content: 36.32

Gene sequence:

>570_bases
TTGATGGTTTTGATTATAGATAATTACGACTCTTTTACCTATAATCTCTATCAATACGTAGGAGAAATGAAAGAGGAGGT
CATGGTGGTGAGAAATGATGAAATAACAGTGGAAGAGGTTGCAAAACTAAATCCTAATAAAATTATATTATCGCCAGGAC
CGGGAAGACCGGAAAATGCAGGAGTATGCGTCGAATTGATTAAAAATTTGGGTCAAAAAGTTCCAATGTTAGGGATATGT
CTTGGACATCAGGCTATTGGATACGCGTACGGAGCGAAAATTGTAAAAGCAGATAGGATAATGCATGGAAAAACTTCTCT
TATCTTTCACAATGGCAGAGGAATATTTAAAAATATAAAAAATCCAATTGAAGGAATGAGATACCATTCGCTGGTTATTG
ATAGAAATACTTTACCTGAGGAGTTGGAAATAACAGCTCAGACGGAGGAAGGGGTGATTATGGGGGTAAGGCATAGAAAA
TACCCTGTGTATGGTTTACAGTTTCATCCAGAGTCTATTTTGACAGAACAAGGAAAGGAGATATTGAGAAATTTTTTGGA
GGTGTTTTAA

Upstream 100 bases:

>100_bases
CTGCTTATTTTCAAGCAGGAGCAGGTATTGTGTATGACTCAATTCCTGAGATGGAATACTATGAAATTTTAAATAAAGTG
ATGGTACTTAAGGAGGTTCT

Downstream 100 bases:

>100_bases
ATGTTGCAGGAGGCGATTAAAAAAATTGTATTAAAAGAAAATCTTGATGAAAAAGAAGCTTATGAAGTTATGGGGGAAAT
TATGAGTGGGAATGGCACTC

Product: anthranilate/para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MMVLIIDNYDSFTYNLYQYVGEMKEEVMVVRNDEITVEEVAKLNPNKIILSPGPGRPENAGVCVELIKNLGQKVPMLGIC
LGHQAIGYAYGAKIVKADRIMHGKTSLIFHNGRGIFKNIKNPIEGMRYHSLVIDRNTLPEELEITAQTEEGVIMGVRHRK
YPVYGLQFHPESILTEQGKEILRNFLEVF

Sequences:

>Translated_189_residues
MMVLIIDNYDSFTYNLYQYVGEMKEEVMVVRNDEITVEEVAKLNPNKIILSPGPGRPENAGVCVELIKNLGQKVPMLGIC
LGHQAIGYAYGAKIVKADRIMHGKTSLIFHNGRGIFKNIKNPIEGMRYHSLVIDRNTLPEELEITAQTEEGVIMGVRHRK
YPVYGLQFHPESILTEQGKEILRNFLEVF
>Mature_189_residues
MMVLIIDNYDSFTYNLYQYVGEMKEEVMVVRNDEITVEEVAKLNPNKIILSPGPGRPENAGVCVELIKNLGQKVPMLGIC
LGHQAIGYAYGAKIVKADRIMHGKTSLIFHNGRGIFKNIKNPIEGMRYHSLVIDRNTLPEELEITAQTEEGVIMGVRHRK
YPVYGLQFHPESILTEQGKEILRNFLEVF

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=51.3513513513513, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=44.3850267379679, Blast_Score=153, Evalue=6e-39,
Organism=Escherichia coli, GI1786215, Length=141, Percent_Identity=34.0425531914894, Blast_Score=80, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=50.2673796791444, Blast_Score=200, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=29.7169811320755, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323873, Length=146, Percent_Identity=30.1369863013699, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281365319, Length=114, Percent_Identity=30.7017543859649, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21461; Mature: 21461

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVLIIDNYDSFTYNLYQYVGEMKEEVMVVRNDEITVEEVAKLNPNKIILSPGPGRPENA
CEEEEEECCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCC
GVCVELIKNLGQKVPMLGICLGHQAIGYAYGAKIVKADRIMHGKTSLIFHNGRGIFKNIK
CHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCEEEEHHHEECCCEEEEEECCCCHHHHHC
NPIEGMRYHSLVIDRNTLPEELEITAQTEEGVIMGVRHRKYPVYGLQFHPESILTEQGKE
CHHHCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCHHHHHHHHHH
ILRNFLEVF
HHHHHHHHC
>Mature Secondary Structure
MMVLIIDNYDSFTYNLYQYVGEMKEEVMVVRNDEITVEEVAKLNPNKIILSPGPGRPENA
CEEEEEECCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCC
GVCVELIKNLGQKVPMLGICLGHQAIGYAYGAKIVKADRIMHGKTSLIFHNGRGIFKNIK
CHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCEEEEHHHEECCCEEEEEECCCCHHHHHC
NPIEGMRYHSLVIDRNTLPEELEITAQTEEGVIMGVRHRKYPVYGLQFHPESILTEQGKE
CHHHCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCHHHHHHHHHH
ILRNFLEVF
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]