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The map label for this gene is trpD

Identifier: 20808010

GI number: 20808010

Start: 1537633

End: 1538652

Strand: Reverse

Name: trpD

Synonym: TTE1581

Alternate gene names: 20808010

Gene position: 1538652-1537633 (Counterclockwise)

Preceding gene: 20808011

Following gene: 20808009

Centisome position: 57.21

GC content: 40.1

Gene sequence:

>1020_bases
ATGTTGCAGGAGGCGATTAAAAAAATTGTATTAAAAGAAAATCTTGATGAAAAAGAAGCTTATGAAGTTATGGGGGAAAT
TATGAGTGGGAATGGCACTCCTTCTTTAATAGGAGGTCTATTGATAGGACTTAGATTAAAAGGGGAAAGTGTGGAAGAGA
TAACAGGTTTTGCAAAAGCCATGAGGGACAATGCAGTAAAACTGCAATTGGATGCTGACTACGTCATTGATACCTGTGGT
ACAGGTGGGGACGGGGGAAAGACTTTTAATATTTCCACTGCTGTAGCTATAATTGCCTCTGCTGCGGGTGTAAAAGTTGC
AAAACATGGCAACAGAGCTGTTTCGAGCAAGAGCGGCAGTGCTGATGTTTTGAGGGAATTGGGATTTAATATAGAAGCTG
AACCCATGTATACAAAGAAAATGATAGAGGAAAAAGGAATGGGATTTCTCTTTGCACCTTTATACCATAGGGCGATGAAG
AACGTACTTCCAATAAGGAGGGAATTGGGAACGAGGACAGTTTTTAACTTACTTGGGCCTTTGACAAATCCTGCACCTAT
AAAAGGACAGGTATTAGGGGTGTATGATAGAAATCTAACTCATCCGATAGCGGAAGTGCTTCTTAAGCTTGGAATAGAAA
GAGCGATGGTAGTGCACGGATTTGATGGGCTTGATGAAATAACTACTACGGCTCCAACCTATGTTAGTGAAGTAAAAGAA
GGAGAAATCTTTGATTACGTAATAGACCCTTTAGACTTTGATATTCCTTATTCCAAGCCTGAAGACCTGAAAGGAAAAGG
ACCGAGGGAGAATGCAGAAATAATTATTGACATATTAAAAGGTCAAAAAGGACCTCGAAGAGATATAGTGGTTTTAAACA
CCGCAGCGGCTTTATACGTGGGCAAGTTGGTTGAAAACTTAAAAGAAGGTGTTGAACTTGCGGAAAGGCTTCTTAATAGC
GGTTTGGCTTATGAGAGGTTTTTGGAGATTTTAGGCTACCAGAGGAGGATTATTTCATGA

Upstream 100 bases:

>100_bases
GCATAGAAAATACCCTGTGTATGGTTTACAGTTTCATCCAGAGTCTATTTTGACAGAACAAGGAAAGGAGATATTGAGAA
ATTTTTTGGAGGTGTTTTAA

Downstream 100 bases:

>100_bases
TTCTAGAGGAAATTGTGAATTTTAAAAAAGAAGAAGTGAGGAAGAAAAAAGAGTTAAAGCCTTACAACGAATTGCTAAAT
GTCAACGCAGTATACAGAGG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLQEAIKKIVLKENLDEKEAYEVMGEIMSGNGTPSLIGGLLIGLRLKGESVEEITGFAKAMRDNAVKLQLDADYVIDTCG
TGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLRELGFNIEAEPMYTKKMIEEKGMGFLFAPLYHRAMK
NVLPIRRELGTRTVFNLLGPLTNPAPIKGQVLGVYDRNLTHPIAEVLLKLGIERAMVVHGFDGLDEITTTAPTYVSEVKE
GEIFDYVIDPLDFDIPYSKPEDLKGKGPRENAEIIIDILKGQKGPRRDIVVLNTAAALYVGKLVENLKEGVELAERLLNS
GLAYERFLEILGYQRRIIS

Sequences:

>Translated_339_residues
MLQEAIKKIVLKENLDEKEAYEVMGEIMSGNGTPSLIGGLLIGLRLKGESVEEITGFAKAMRDNAVKLQLDADYVIDTCG
TGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLRELGFNIEAEPMYTKKMIEEKGMGFLFAPLYHRAMK
NVLPIRRELGTRTVFNLLGPLTNPAPIKGQVLGVYDRNLTHPIAEVLLKLGIERAMVVHGFDGLDEITTTAPTYVSEVKE
GEIFDYVIDPLDFDIPYSKPEDLKGKGPRENAEIIIDILKGQKGPRRDIVVLNTAAALYVGKLVENLKEGVELAERLLNS
GLAYERFLEILGYQRRIIS
>Mature_339_residues
MLQEAIKKIVLKENLDEKEAYEVMGEIMSGNGTPSLIGGLLIGLRLKGESVEEITGFAKAMRDNAVKLQLDADYVIDTCG
TGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLRELGFNIEAEPMYTKKMIEEKGMGFLFAPLYHRAMK
NVLPIRRELGTRTVFNLLGPLTNPAPIKGQVLGVYDRNLTHPIAEVLLKLGIERAMVVHGFDGLDEITTTAPTYVSEVKE
GEIFDYVIDPLDFDIPYSKPEDLKGKGPRENAEIIIDILKGQKGPRRDIVVLNTAAALYVGKLVENLKEGVELAERLLNS
GLAYERFLEILGYQRRIIS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=327, Percent_Identity=39.7553516819572, Blast_Score=215, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6320561, Length=277, Percent_Identity=33.9350180505415, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_THETN (Q8R9M6)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623181.1
- ProteinModelPortal:   Q8R9M6
- SMR:   Q8R9M6
- GeneID:   996018
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1581
- NMPDR:   fig|273068.3.peg.1528
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   TTEN273068:TTE1581-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37017; Mature: 37017

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQEAIKKIVLKENLDEKEAYEVMGEIMSGNGTPSLIGGLLIGLRLKGESVEEITGFAKA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHH
MRDNAVKLQLDADYVIDTCGTGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGS
HHCCCEEEEECCCEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHCCCCCCCCCCCC
ADVLRELGFNIEAEPMYTKKMIEEKGMGFLFAPLYHRAMKNVLPIRRELGTRTVFNLLGP
HHHHHHCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTNPAPIKGQVLGVYDRNLTHPIAEVLLKLGIERAMVVHGFDGLDEITTTAPTYVSEVKE
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHCHHHEEEEECCCCHHHHHCCCCHHHHHHCC
GEIFDYVIDPLDFDIPYSKPEDLKGKGPRENAEIIIDILKGQKGPRRDIVVLNTAAALYV
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
GKLVENLKEGVELAERLLNSGLAYERFLEILGYQRRIIS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQEAIKKIVLKENLDEKEAYEVMGEIMSGNGTPSLIGGLLIGLRLKGESVEEITGFAKA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHH
MRDNAVKLQLDADYVIDTCGTGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGS
HHCCCEEEEECCCEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCHHHHCCCCCCCCCCCC
ADVLRELGFNIEAEPMYTKKMIEEKGMGFLFAPLYHRAMKNVLPIRRELGTRTVFNLLGP
HHHHHHCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTNPAPIKGQVLGVYDRNLTHPIAEVLLKLGIERAMVVHGFDGLDEITTTAPTYVSEVKE
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHCHHHEEEEECCCCHHHHHCCCCHHHHHHCC
GEIFDYVIDPLDFDIPYSKPEDLKGKGPRENAEIIIDILKGQKGPRRDIVVLNTAAALYV
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
GKLVENLKEGVELAERLLNSGLAYERFLEILGYQRRIIS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336