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The map label for this gene is TrpB [H]

Identifier: 20808007

GI number: 20808007

Start: 1535081

End: 1536256

Strand: Reverse

Name: TrpB [H]

Synonym: TTE1578

Alternate gene names: 20808007

Gene position: 1536256-1535081 (Counterclockwise)

Preceding gene: 20808008

Following gene: 20808006

Centisome position: 57.12

GC content: 43.62

Gene sequence:

>1176_bases
ATGAAAGGTAGGTTTGGAAGGTTTGGAGGGCAGTATGTGCCGGAGACAGTTATGAATGCTCTTATAGAGTTAGAGAGAGA
ATTTGAAGAGGCAAAGAAGGACGAAAAATTCATGGAGGAGTACAGATATTATCTTAAAGAATACTCAGGAAGGCCTACGC
CTTTGTATTATGCAGAAAATCTCACTAAAAGGCTGGGTGGCGCGAAAATTTATCTAAAAAGAGAAGACCTCAACCACACA
GGAGCTCACAAGATAAACAACGTATTGGGACAGGTGCTTTTGGCAAAGCGAATGGGCAAAAAGAGAATTATAGCTGAAAC
AGGAGCAGGACAGCACGGAGTTGCTACTGCTACAGCTGCTGCTATGTTTGGAATGGAATGCGAAATATTCATGGGAGAAG
AAGATATAAAAAGGCAGGCACTAAATGTGTTTAGGATGAAACTTTTAGGGGCAAAAGTGACAGCTGTTACTTCAGGTACA
AGGACATTGAAAGATGCAGTGAATGAGGCCATAAGGGATTGGGTCACTAATATAGAAACTACCTTCTATGTGATTGGCTC
TGTGGTAGGACCTCATCCATATCCCACTATGGTAAGAGATTTTCAGCGAGTTATAGGGGATGAGACGAAAGAGCAAATCC
TTGAAAAAGAAGGTCGACTTCCTGATTATGTGGTTGCCTGCGTGGGAGGAGGCAGTAATGCCATGGGAATATTCTATCCT
TTTATTGAAGATAAGGGAGTGAAGTTAGTGGGGGTAGAAGCGGCAGGAGAAGGTATAGAGACAGGGAAACACGCTTCAGC
AATGGCAAAAGGTTCAGTTGGGGTGCTCCACGGCATGATGACCTACCTCCTTCAAGATGAGGAGGGGAAAATTCTACCTG
TTCATTCGATATCGGCAGGGCTTGATTATCCAGGAGTGGGGCCAGAACACGCTTATTTGAAGGAGATAGGAAGGGCAGAG
TACGTGTATGCTACAGATGAAGAGGCTTTGGCAGCCTTTATGGACCTGTCTCGGACAGAAGGAATAATACCAGCATTAGA
AAGTGCACATGCTCTGGCTTATGCTATGAAATTGGCTAAGAAATTGGATGAAGACAAGATAATTGTAGTAAATCTTTCTG
GAAGAGGGGACAAAGATGTAAATACCGTCGCAAAAGTAATGGGGGTGGAATTGTGA

Upstream 100 bases:

>100_bases
TAAGACCTTACGCCGTCGATGTGTCGAGTGGCGTTGAGGTTGGGGGATATAAGGACTTTAATAAAATGAAGTCATTTATT
GAGAAAGTGAGGGGTGTTGT

Downstream 100 bases:

>100_bases
ATAGAATTGATAGAAGGTTTGATGACCTCAAAAAAGAAGGTAAAAAAGCCCTTATAACTTTCATTACTGCCGGAGACCCA
GACATTGACACAACTTATGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKGRFGRFGGQYVPETVMNALIELEREFEEAKKDEKFMEEYRYYLKEYSGRPTPLYYAENLTKRLGGAKIYLKREDLNHT
GAHKINNVLGQVLLAKRMGKKRIIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQALNVFRMKLLGAKVTAVTSGT
RTLKDAVNEAIRDWVTNIETTFYVIGSVVGPHPYPTMVRDFQRVIGDETKEQILEKEGRLPDYVVACVGGGSNAMGIFYP
FIEDKGVKLVGVEAAGEGIETGKHASAMAKGSVGVLHGMMTYLLQDEEGKILPVHSISAGLDYPGVGPEHAYLKEIGRAE
YVYATDEEALAAFMDLSRTEGIIPALESAHALAYAMKLAKKLDEDKIIVVNLSGRGDKDVNTVAKVMGVEL

Sequences:

>Translated_391_residues
MKGRFGRFGGQYVPETVMNALIELEREFEEAKKDEKFMEEYRYYLKEYSGRPTPLYYAENLTKRLGGAKIYLKREDLNHT
GAHKINNVLGQVLLAKRMGKKRIIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQALNVFRMKLLGAKVTAVTSGT
RTLKDAVNEAIRDWVTNIETTFYVIGSVVGPHPYPTMVRDFQRVIGDETKEQILEKEGRLPDYVVACVGGGSNAMGIFYP
FIEDKGVKLVGVEAAGEGIETGKHASAMAKGSVGVLHGMMTYLLQDEEGKILPVHSISAGLDYPGVGPEHAYLKEIGRAE
YVYATDEEALAAFMDLSRTEGIIPALESAHALAYAMKLAKKLDEDKIIVVNLSGRGDKDVNTVAKVMGVEL
>Mature_391_residues
MKGRFGRFGGQYVPETVMNALIELEREFEEAKKDEKFMEEYRYYLKEYSGRPTPLYYAENLTKRLGGAKIYLKREDLNHT
GAHKINNVLGQVLLAKRMGKKRIIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQALNVFRMKLLGAKVTAVTSGT
RTLKDAVNEAIRDWVTNIETTFYVIGSVVGPHPYPTMVRDFQRVIGDETKEQILEKEGRLPDYVVACVGGGSNAMGIFYP
FIEDKGVKLVGVEAAGEGIETGKHASAMAKGSVGVLHGMMTYLLQDEEGKILPVHSISAGLDYPGVGPEHAYLKEIGRAE
YVYATDEEALAAFMDLSRTEGIIPALESAHALAYAMKLAKKLDEDKIIVVNLSGRGDKDVNTVAKVMGVEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=58.0729166666667, Blast_Score=464, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=61.8181818181818, Blast_Score=501, Evalue=1e-142,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42973; Mature: 42973

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRFGRFGGQYVPETVMNALIELEREFEEAKKDEKFMEEYRYYLKEYSGRPTPLYYAEN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LTKRLGGAKIYLKREDLNHTGAHKINNVLGQVLLAKRMGKKRIIAETGAGQHGVATATAA
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AMFGMECEIFMGEEDIKRQALNVFRMKLLGAKVTAVTSGTRTLKDAVNEAIRDWVTNIET
HHHCCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
TFYVIGSVVGPHPYPTMVRDFQRVIGDETKEQILEKEGRLPDYVVACVGGGSNAMGIFYP
HHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEE
FIEDKGVKLVGVEAAGEGIETGKHASAMAKGSVGVLHGMMTYLLQDEEGKILPVHSISAG
EECCCCCEEEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
LDYPGVGPEHAYLKEIGRAEYVYATDEEALAAFMDLSRTEGIIPALESAHALAYAMKLAK
CCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KLDEDKIIVVNLSGRGDKDVNTVAKVMGVEL
HCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKGRFGRFGGQYVPETVMNALIELEREFEEAKKDEKFMEEYRYYLKEYSGRPTPLYYAEN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LTKRLGGAKIYLKREDLNHTGAHKINNVLGQVLLAKRMGKKRIIAETGAGQHGVATATAA
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AMFGMECEIFMGEEDIKRQALNVFRMKLLGAKVTAVTSGTRTLKDAVNEAIRDWVTNIET
HHHCCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
TFYVIGSVVGPHPYPTMVRDFQRVIGDETKEQILEKEGRLPDYVVACVGGGSNAMGIFYP
HHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEE
FIEDKGVKLVGVEAAGEGIETGKHASAMAKGSVGVLHGMMTYLLQDEEGKILPVHSISAG
EECCCCCEEEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
LDYPGVGPEHAYLKEIGRAEYVYATDEEALAAFMDLSRTEGIIPALESAHALAYAMKLAK
CCCCCCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KLDEDKIIVVNLSGRGDKDVNTVAKVMGVEL
HCCCCCEEEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA