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The map label for this gene is AroA3 [H]

Identifier: 20808005

GI number: 20808005

Start: 1533501

End: 1534283

Strand: Reverse

Name: AroA3 [H]

Synonym: TTE1576

Alternate gene names: 20808005

Gene position: 1534283-1533501 (Counterclockwise)

Preceding gene: 20808006

Following gene: 20808004

Centisome position: 57.05

GC content: 39.85

Gene sequence:

>783_bases
ATGGAATTTAAAATAGTGGGAAATAAAGATAAAAAGCCGAGTGTAAAAATAGGGGAGGTAACCGTTGGAGAGGGGAAACT
TATAATTGCAGGCCCTTGTGCAGTGGAAAGTGAAGAAATGCTTGTAAAGACAGCCGAAAAGGTCAAAAGCTGTGGAGCCA
ATGCATTAAGGGGCGGGGCTTATAAGCCTCGCACATCTCCCTATTCCTTTCAAGGTTTGGGCATTGAAGGGCTCAAACTC
TTGAGAAAAGTAGGAGATGTTTTTAAACTCCCTATTGTTACAGAGGTTTTAGATGTGAGGGATGTGGAGATTGTTCAAGA
ATACGCAGATGTTTTGCAGATCGGTTCAAGGAATATGCAAAATTTTCCACTTCTAAAAGAGGTAGGGAAGACTAAAAAAA
CTGTCCTTTTAAAGAGAGGGTTTTCTGCAACTTATGAAGAATGGCTTTATGCAGCGGAATACATTGCAATTGAAGGGAAT
ACCAGCATCATTTTGTGTGAAAGGGGTATAAGGACGTTTGAAACTTATACAAGAAGTACCTTGGATATAGCAGCAGTTCC
TGTAATCCATGAACTTTCAAATCTTCCTATTATTGTAGATGTAAGTCACGGTACAGGGAAGAGAAGCTTAATTATCCCAA
TGGCAAAGGCAGCCCTCTGTGCTGGTGCTGACGGAATAATGGTAGAAGTGCATCCTGATCCTGAAAAAGCTTTGTCAGAT
GGTGAGCAGTCTCTCAATTTTCTTGAATTTGAAAATTTAATGAGAGAAATAAAAAGGTGTTGA

Upstream 100 bases:

>100_bases
TGTAGAAAGAATTGCTAAGGGGTATAATAGATGTGAAATGTTAAAAGAGGTAAAGGAATTTGTGTTAAGCTTAAGAGAAG
TCTTGTGAAAGGTGATAAGT

Downstream 100 bases:

>100_bases
CATTTGAAGGAAATGAGGCTATAATTTAAGTATCAGATAATGATTATCCATAGAAAATAATTTTAGAAAGCAGGGATAAT
ATGGTAGAGGTAGGCAAAAA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MEFKIVGNKDKKPSVKIGEVTVGEGKLIIAGPCAVESEEMLVKTAEKVKSCGANALRGGAYKPRTSPYSFQGLGIEGLKL
LRKVGDVFKLPIVTEVLDVRDVEIVQEYADVLQIGSRNMQNFPLLKEVGKTKKTVLLKRGFSATYEEWLYAAEYIAIEGN
TSIILCERGIRTFETYTRSTLDIAAVPVIHELSNLPIIVDVSHGTGKRSLIIPMAKAALCAGADGIMVEVHPDPEKALSD
GEQSLNFLEFENLMREIKRC

Sequences:

>Translated_260_residues
MEFKIVGNKDKKPSVKIGEVTVGEGKLIIAGPCAVESEEMLVKTAEKVKSCGANALRGGAYKPRTSPYSFQGLGIEGLKL
LRKVGDVFKLPIVTEVLDVRDVEIVQEYADVLQIGSRNMQNFPLLKEVGKTKKTVLLKRGFSATYEEWLYAAEYIAIEGN
TSIILCERGIRTFETYTRSTLDIAAVPVIHELSNLPIIVDVSHGTGKRSLIIPMAKAALCAGADGIMVEVHPDPEKALSD
GEQSLNFLEFENLMREIKRC
>Mature_260_residues
MEFKIVGNKDKKPSVKIGEVTVGEGKLIIAGPCAVESEEMLVKTAEKVKSCGANALRGGAYKPRTSPYSFQGLGIEGLKL
LRKVGDVFKLPIVTEVLDVRDVEIVQEYADVLQIGSRNMQNFPLLKEVGKTKKTVLLKRGFSATYEEWLYAAEYIAIEGN
TSIILCERGIRTFETYTRSTLDIAAVPVIHELSNLPIIVDVSHGTGKRSLIIPMAKAALCAGADGIMVEVHPDPEKALSD
GEQSLNFLEFENLMREIKRC

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=208, Percent_Identity=25.9615384615385, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 28558; Mature: 28558

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKIVGNKDKKPSVKIGEVTVGEGKLIIAGPCAVESEEMLVKTAEKVKSCGANALRGGA
CEEEEECCCCCCCCEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHCCCC
YKPRTSPYSFQGLGIEGLKLLRKVGDVFKLPIVTEVLDVRDVEIVQEYADVLQIGSRNMQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NFPLLKEVGKTKKTVLLKRGFSATYEEWLYAAEYIAIEGNTSIILCERGIRTFETYTRST
CCCHHHHHCCHHHHEEEECCCCHHHHHHHHHHEEEEEECCCEEEEECCCCHHHHHHHCCH
LDIAAVPVIHELSNLPIIVDVSHGTGKRSLIIPMAKAALCAGADGIMVEVHPDPEKALSD
HHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHCCCCCEEEEECCCHHHHHCC
GEQSLNFLEFENLMREIKRC
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFKIVGNKDKKPSVKIGEVTVGEGKLIIAGPCAVESEEMLVKTAEKVKSCGANALRGGA
CEEEEECCCCCCCCEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHCCCC
YKPRTSPYSFQGLGIEGLKLLRKVGDVFKLPIVTEVLDVRDVEIVQEYADVLQIGSRNMQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
NFPLLKEVGKTKKTVLLKRGFSATYEEWLYAAEYIAIEGNTSIILCERGIRTFETYTRST
CCCHHHHHCCHHHHEEEECCCCHHHHHHHHHHEEEEEECCCEEEEECCCCHHHHHHHCCH
LDIAAVPVIHELSNLPIIVDVSHGTGKRSLIIPMAKAALCAGADGIMVEVHPDPEKALSD
HHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHCCCCCEEEEECCCHHHHHCC
GEQSLNFLEFENLMREIKRC
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]