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The map label for this gene is FtsY [H]

Identifier: 20807911

GI number: 20807911

Start: 1435691

End: 1436578

Strand: Reverse

Name: FtsY [H]

Synonym: TTE1464

Alternate gene names: 20807911

Gene position: 1436578-1435691 (Counterclockwise)

Preceding gene: 20807912

Following gene: 20807910

Centisome position: 53.42

GC content: 37.95

Gene sequence:

>888_bases
ATGCTTAATTTTCTGCAAAAATTTAAAGAAAATTTAACTGCGAAGTTAAATGAGGTATTAAGCTTTGGCAAAAAAGTAGA
TGAGGAATTGTTTGAAGAACTGGAAGAAGCACTTATACTAGCTGATGTAGGGGTTGATACAACTTACAAGATTATTCAAT
CGCTTAAGCAGAAGACAAAGGAGGAAAAGATCTTTGAAGCAAGCAAAGTAAGGGAACTTTTGGCACAAGAGATATATGAG
ATTTTACAGAAAGATGTAGAGCCTTTTGTTTTGACTTCGCCAATGGTGATTTTGATAGTAGGGGTAAATGGGGTAGGAAA
AACTACTACTATTGGAAAATTAGCTCATTTGTATAAAAAGCAGGGTAAGAGCGTAATGATGGTGGCAGCTGATACCTTCA
GAGCCGCTGCCATTGACCAGCTAGAGGTGTGGGCGAAAAGAGTAAATTGCCCTATAATAAAGCATCAGGAAGGTTCTGAT
CCGGCATCAGTGGTGTTTGACGGTCTTCAGTCAGCAAAAGCTAGAGGTATAGACGTAGTTATTTGCGACACTGCTGGAAG
GCTTCACAACAAGAAAAATTTAATGGAAGAACTTAGAAAAATACGAAAAGTTATAGACAGGGAGTACAGCGAGGCTAGAG
TGGAAACTTTTCTAGTTTTAGATGCTACTACTGGTCAGAATGCTCTACAGCAGGCTAAGATATTTAAGGAAGTCGCTGAC
ATAACAGGAATAATACTTACTAAACTAGATGGAACTGCCAAAGGTGGTATTGTCATAGCTATAAAAGAAGAACTTAACTT
GCCTATAAGATATATAGGAATTGGGGAAGGAATGGAGGATTTGCAAGCTTTTGACGCAAAATCCTTTGTTTCTGCTATTT
TTCAGTGA

Upstream 100 bases:

>100_bases
GCAGATGCTATATACGGCGTCACCATGCAGGAAAAGGGAGTTTCAAAGCTTTTATCTATCAAGCTAAATACTGAAGATAG
GTCAGGAGGGTTGCTCACAC

Downstream 100 bases:

>100_bases
ATAAAACTGCAAAAAAATGAAAAAACAGAGTTGACAAAAATGAGGGCTTCATATAAAATCTTAATGTAAAGGTCAAAACC
TTAACGGGTGGGATTCCTTG

Product: Signal recognition particle GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLNFLQKFKENLTAKLNEVLSFGKKVDEELFEELEEALILADVGVDTTYKIIQSLKQKTKEEKIFEASKVRELLAQEIYE
ILQKDVEPFVLTSPMVILIVGVNGVGKTTTIGKLAHLYKKQGKSVMMVAADTFRAAAIDQLEVWAKRVNCPIIKHQEGSD
PASVVFDGLQSAKARGIDVVICDTAGRLHNKKNLMEELRKIRKVIDREYSEARVETFLVLDATTGQNALQQAKIFKEVAD
ITGIILTKLDGTAKGGIVIAIKEELNLPIRYIGIGEGMEDLQAFDAKSFVSAIFQ

Sequences:

>Translated_295_residues
MLNFLQKFKENLTAKLNEVLSFGKKVDEELFEELEEALILADVGVDTTYKIIQSLKQKTKEEKIFEASKVRELLAQEIYE
ILQKDVEPFVLTSPMVILIVGVNGVGKTTTIGKLAHLYKKQGKSVMMVAADTFRAAAIDQLEVWAKRVNCPIIKHQEGSD
PASVVFDGLQSAKARGIDVVICDTAGRLHNKKNLMEELRKIRKVIDREYSEARVETFLVLDATTGQNALQQAKIFKEVAD
ITGIILTKLDGTAKGGIVIAIKEELNLPIRYIGIGEGMEDLQAFDAKSFVSAIFQ
>Mature_295_residues
MLNFLQKFKENLTAKLNEVLSFGKKVDEELFEELEEALILADVGVDTTYKIIQSLKQKTKEEKIFEASKVRELLAQEIYE
ILQKDVEPFVLTSPMVILIVGVNGVGKTTTIGKLAHLYKKQGKSVMMVAADTFRAAAIDQLEVWAKRVNCPIIKHQEGSD
PASVVFDGLQSAKARGIDVVICDTAGRLHNKKNLMEELRKIRKVIDREYSEARVETFLVLDATTGQNALQQAKIFKEVAD
ITGIILTKLDGTAKGGIVIAIKEELNLPIRYIGIGEGMEDLQAFDAKSFVSAIFQ

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=271, Percent_Identity=31.7343173431734, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI226371618, Length=230, Percent_Identity=33.9130434782609, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI23308697, Length=306, Percent_Identity=29.0849673202614, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI295424842, Length=306, Percent_Identity=29.0849673202614, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=32.5925925925926, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789874, Length=292, Percent_Identity=54.4520547945205, Blast_Score=294, Evalue=4e-81,
Organism=Escherichia coli, GI1788963, Length=299, Percent_Identity=33.1103678929766, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=271, Percent_Identity=30.2583025830258, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI193206261, Length=297, Percent_Identity=29.96632996633, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=271, Percent_Identity=36.90036900369, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17647949, Length=271, Percent_Identity=32.8413284132841, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24641198, Length=302, Percent_Identity=28.8079470198675, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 32816; Mature: 32816

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFLQKFKENLTAKLNEVLSFGKKVDEELFEELEEALILADVGVDTTYKIIQSLKQKTK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EEKIFEASKVRELLAQEIYEILQKDVEPFVLTSPMVILIVGVNGVGKTTTIGKLAHLYKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHH
QGKSVMMVAADTFRAAAIDQLEVWAKRVNCPIIKHQEGSDPASVVFDGLQSAKARGIDVV
CCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEE
ICDTAGRLHNKKNLMEELRKIRKVIDREYSEARVETFLVLDATTGQNALQQAKIFKEVAD
EECCCHHHCCHHHHHHHHHHHHHHHHCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
ITGIILTKLDGTAKGGIVIAIKEELNLPIRYIGIGEGMEDLQAFDAKSFVSAIFQ
HHHHHHEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNFLQKFKENLTAKLNEVLSFGKKVDEELFEELEEALILADVGVDTTYKIIQSLKQKTK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EEKIFEASKVRELLAQEIYEILQKDVEPFVLTSPMVILIVGVNGVGKTTTIGKLAHLYKK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHH
QGKSVMMVAADTFRAAAIDQLEVWAKRVNCPIIKHQEGSDPASVVFDGLQSAKARGIDVV
CCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEE
ICDTAGRLHNKKNLMEELRKIRKVIDREYSEARVETFLVLDATTGQNALQQAKIFKEVAD
EECCCHHHCCHHHHHHHHHHHHHHHHCHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
ITGIILTKLDGTAKGGIVIAIKEELNLPIRYIGIGEGMEDLQAFDAKSFVSAIFQ
HHHHHHEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]