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The map label for this gene is CheC2 [H]

Identifier: 20807876

GI number: 20807876

Start: 1407107

End: 1408207

Strand: Reverse

Name: CheC2 [H]

Synonym: TTE1429

Alternate gene names: 20807876

Gene position: 1408207-1407107 (Counterclockwise)

Preceding gene: 20807877

Following gene: 20807875

Centisome position: 52.36

GC content: 38.78

Gene sequence:

>1101_bases
ATGAAGAAAGTAAATGAGTTCTTGTCGCAAGAGGAAATAAACGCTCTCTTAAAAGGGCTCCAAGAAGAAACACAGGAAAA
AAAAGAACTGACTGATGAAGAAAAGGACATATTGGGGGAAATAGGAAATATAAGCTTTGGTACATCTGCTACTACTTTGT
ATACTCTTTTGAGGAACAAAGTTACCATCACAACTCCGAAGGTTTCCGTGCTCTCATGGGACCAGTTAAAAGAAGAATTC
AACATACCTTATGTTGGAGTACAAGTAGAGTACACAGAAGGATTAAAAGGGTATAACCTTCTTATTTTGAAAAAAGAAGA
TGCGTTAAAAATCACTGACCTCATGATGGGAGGAGATGGTAAAGTAGAAGAAGGAGAGATAACAGACCTTCACTTAAGCG
CTGTCGGTGAAGCAATGAATCAAATGATTGGTTCAGCTGCTACATCTCTTTCAACTCTTTTGAACAAGAAGATAAACATA
TCTCCTCCGAAGGCCTTTATAGTGGATTTTTCAACAGCTTTGCCGGAGGATGTAGCATTTCCTCAAGGAGATGTTGTCAG
AGTTGCTTTTAAGATGGAAGTGGGAGATATAATTGACAGCGAAATAATGCAGCTTATACCTTTTGACTTTGCTAAAGAGC
TTGTTAAGAGCGTTCTTCAACAGGCTACTACTTCTACTTCACCGCCTGCAGAAGTTAAAGAGATGAAAAAAGAAAGCAAA
GGAGAATCTGAAGAGAAAATGGCTAGTGAAAAGGCCATTAAAAAGGAAGAAAAGGTAAATGTAAGTCCTGTAATTTTCCA
GAATTTTGATGAAGAGCCTCAGCAGGAGGCGAAAGGAGAGAGTAAGAATTTGGATTTGATACTGGACGTGCCCCTTACTA
TCACTGTTGAGCTTGGCAAAACTAAAAAGTTAATAAAAGATATACTAGAACTGACAGAGGGTTCTATAATAGAGCTTGAC
AAACTGGCAGGAGAGCCTGTAGATATACTGGCAAACGGCAAGTACATTGCCAAAGGAGAAGTAGTGGTGATTGATGAAAA
TTTTGGGGTGCGGATTACAGACATTGTTCATCCGGGCAAGAGAATTGGCAATATAGAATAA

Upstream 100 bases:

>100_bases
GTAGAGGTGATAATAGATAAAAAAGTAAAATTTAAAGGAATACCTGGAATTAAAAGTAAGCGATACAGCGTCAAAATAAC
AGAAGTTATTTACAAAGGAG

Downstream 100 bases:

>100_bases
AAGACAAGGAGGAATCATTGTGAGCAAAATATTGATTGTCGACGATGCTGCTTTTATGAGGATGATGATAAAAGATATAA
TTTCAAAGAACAATCTTGGA

Product: flagellar motor switch protein

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKKVNEFLSQEEINALLKGLQEETQEKKELTDEEKDILGEIGNISFGTSATTLYTLLRNKVTITTPKVSVLSWDQLKEEF
NIPYVGVQVEYTEGLKGYNLLILKKEDALKITDLMMGGDGKVEEGEITDLHLSAVGEAMNQMIGSAATSLSTLLNKKINI
SPPKAFIVDFSTALPEDVAFPQGDVVRVAFKMEVGDIIDSEIMQLIPFDFAKELVKSVLQQATTSTSPPAEVKEMKKESK
GESEEKMASEKAIKKEEKVNVSPVIFQNFDEEPQQEAKGESKNLDLILDVPLTITVELGKTKKLIKDILELTEGSIIELD
KLAGEPVDILANGKYIAKGEVVVIDENFGVRITDIVHPGKRIGNIE

Sequences:

>Translated_366_residues
MKKVNEFLSQEEINALLKGLQEETQEKKELTDEEKDILGEIGNISFGTSATTLYTLLRNKVTITTPKVSVLSWDQLKEEF
NIPYVGVQVEYTEGLKGYNLLILKKEDALKITDLMMGGDGKVEEGEITDLHLSAVGEAMNQMIGSAATSLSTLLNKKINI
SPPKAFIVDFSTALPEDVAFPQGDVVRVAFKMEVGDIIDSEIMQLIPFDFAKELVKSVLQQATTSTSPPAEVKEMKKESK
GESEEKMASEKAIKKEEKVNVSPVIFQNFDEEPQQEAKGESKNLDLILDVPLTITVELGKTKKLIKDILELTEGSIIELD
KLAGEPVDILANGKYIAKGEVVVIDENFGVRITDIVHPGKRIGNIE
>Mature_366_residues
MKKVNEFLSQEEINALLKGLQEETQEKKELTDEEKDILGEIGNISFGTSATTLYTLLRNKVTITTPKVSVLSWDQLKEEF
NIPYVGVQVEYTEGLKGYNLLILKKEDALKITDLMMGGDGKVEEGEITDLHLSAVGEAMNQMIGSAATSLSTLLNKKINI
SPPKAFIVDFSTALPEDVAFPQGDVVRVAFKMEVGDIIDSEIMQLIPFDFAKELVKSVLQQATTSTSPPAEVKEMKKESK
GESEEKMASEKAIKKEEKVNVSPVIFQNFDEEPQQEAKGESKNLDLILDVPLTITVELGKTKKLIKDILELTEGSIIELD
KLAGEPVDILANGKYIAKGEVVVIDENFGVRITDIVHPGKRIGNIE

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

Organism=Escherichia coli, GI1788256, Length=120, Percent_Identity=45.8333333333333, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 40385; Mature: 40385

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVNEFLSQEEINALLKGLQEETQEKKELTDEEKDILGEIGNISFGTSATTLYTLLRNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCC
VTITTPKVSVLSWDQLKEEFNIPYVGVQVEYTEGLKGYNLLILKKEDALKITDLMMGGDG
EEEECCCEEEEEHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCEEEEHEEECCCC
KVEEGEITDLHLSAVGEAMNQMIGSAATSLSTLLNKKINISPPKAFIVDFSTALPEDVAF
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCCCCCCC
PQGDVVRVAFKMEVGDIIDSEIMQLIPFDFAKELVKSVLQQATTSTSPPAEVKEMKKESK
CCCCEEEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
GESEEKMASEKAIKKEEKVNVSPVIFQNFDEEPQQEAKGESKNLDLILDVPLTITVELGK
CCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCCCCCEEEECCEEEEEECCC
TKKLIKDILELTEGSIIELDKLAGEPVDILANGKYIAKGEVVVIDENFGVRITDIVHPGK
HHHHHHHHHHHCCCCEEEHHHHCCCCEEEEECCEEEECCEEEEEECCCCEEEEEEECCCH
RIGNIE
HCCCCC
>Mature Secondary Structure
MKKVNEFLSQEEINALLKGLQEETQEKKELTDEEKDILGEIGNISFGTSATTLYTLLRNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCC
VTITTPKVSVLSWDQLKEEFNIPYVGVQVEYTEGLKGYNLLILKKEDALKITDLMMGGDG
EEEECCCEEEEEHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCEEEEHEEECCCC
KVEEGEITDLHLSAVGEAMNQMIGSAATSLSTLLNKKINISPPKAFIVDFSTALPEDVAF
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCCCCCCC
PQGDVVRVAFKMEVGDIIDSEIMQLIPFDFAKELVKSVLQQATTSTSPPAEVKEMKKESK
CCCCEEEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
GESEEKMASEKAIKKEEKVNVSPVIFQNFDEEPQQEAKGESKNLDLILDVPLTITVELGK
CCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCCCCCEEEECCEEEEEECCC
TKKLIKDILELTEGSIIELDKLAGEPVDILANGKYIAKGEVVVIDENFGVRITDIVHPGK
HHHHHHHHHHHCCCCEEEHHHHCCCCEEEEECCEEEECCEEEEEECCCCEEEEEEECCCH
RIGNIE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]