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The map label for this gene is nusA [H]

Identifier: 20807843

GI number: 20807843

Start: 1378153

End: 1379193

Strand: Reverse

Name: nusA [H]

Synonym: TTE1396

Alternate gene names: 20807843

Gene position: 1379193-1378153 (Counterclockwise)

Preceding gene: 20807844

Following gene: 20807842

Centisome position: 51.28

GC content: 41.4

Gene sequence:

>1041_bases
ATGAATGCAGAATTTATTGAGGCATTGAATTCAATATGCGAAGAAAAAGGAATACCTAAAGAGACTATGTTTGAGGCTAT
AGAGGCGGCTTTGGTTTCTGCCTACAGAAAAAATTACGGAACAGCCCAAAACGTGAAGATTGTAATGGACAGAGAGACAG
GAGATGTTAAGGTATATGCCCAAAAGACTGTGGTGGAAGAAGTAAAAAATGACCTTTTGGAAATAAGCTTAGAAGATGCG
AGGAAGATAAATAAAAAATACCAGATTGGTGATATTGTAGATATAGAAGTGACTCCCAAAAACTTTGGCAGGATTGCGGC
ACAGAACGCAAAACAGGTGGTAATACAGAGGATAAGGGAAGCAGAAAGAAATGTGATTTATGAAGAGTTCCTGGCAAAAG
AGACAGAAGTAGTAACTGGGATTGTGACAAGAGCAGCAAAAAATAACGTGCTCATCAATCTAGGAAGGGTGGAGGCGATA
CTTACTCCTTCAGAGCAAATTCCGGGAGAAACTTTTTCACCTGGAGACAGGATAAAGGTGTACATCGTAGAAGTAAAAAA
AACCACAAAAGGACCTCAAATCATAATCTCTCGGTCTCATCCTGGGCTGGTTAAAAGGCTTTTTGAACTAGAATCGCCCG
AGATTCAGCAGGGTATAGTTGAAATAAGGAGCATTGCGAGAGAACCAGGTTCCCGCACAAAAATGGCTGTGTTCAGCAGA
GACCCCAATGTAGACCCTATTGGAGCCTGTGTAGGCTACAAAGGTTCTAGAGTTCAGGCTGTTGTCAATGAATTAAAAGG
AGAAAAGATAGACATTGTGAAGTGGAGTTCAAAACCTCAGGAGTTTATCATGAATGCACTAAGCCCTGCAAAAGCTATAA
GCGTGGAGATTGTAGATGAGAAAGAAAAAGTGGCAAGGGTAATTGTACCAGATTATCAGCTCTCTTTGGCAATAGGTAAA
GAGGGGCAGAATGCGCGGCTAGCAGCGAAGCTCACTGGATGGAAGATAGATATAAAAAGCGAGTCGATGGTCAAAAGTTG
A

Upstream 100 bases:

>100_bases
CCTTCTATGTGAAGGAGAGAAGAGGGAGTTTGAAATGAAGAATGTAAGGCTTGTTAAACCTGTGATAAAGTTTTAAAATT
AAGGAGGGAGAGTAAGCGCA

Downstream 100 bases:

>100_bases
GTGAGGTGGAAAAATGAAAGTAAAAAAAGTTCCGATGAGAATGTGCCTTGGCTGCCAAGAGATGAAGCCTAAAAAAGAGC
TTATACGGATAGTAAGACGC

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNAEFIEALNSICEEKGIPKETMFEAIEAALVSAYRKNYGTAQNVKIVMDRETGDVKVYAQKTVVEEVKNDLLEISLEDA
RKINKKYQIGDIVDIEVTPKNFGRIAAQNAKQVVIQRIREAERNVIYEEFLAKETEVVTGIVTRAAKNNVLINLGRVEAI
LTPSEQIPGETFSPGDRIKVYIVEVKKTTKGPQIIISRSHPGLVKRLFELESPEIQQGIVEIRSIAREPGSRTKMAVFSR
DPNVDPIGACVGYKGSRVQAVVNELKGEKIDIVKWSSKPQEFIMNALSPAKAISVEIVDEKEKVARVIVPDYQLSLAIGK
EGQNARLAAKLTGWKIDIKSESMVKS

Sequences:

>Translated_346_residues
MNAEFIEALNSICEEKGIPKETMFEAIEAALVSAYRKNYGTAQNVKIVMDRETGDVKVYAQKTVVEEVKNDLLEISLEDA
RKINKKYQIGDIVDIEVTPKNFGRIAAQNAKQVVIQRIREAERNVIYEEFLAKETEVVTGIVTRAAKNNVLINLGRVEAI
LTPSEQIPGETFSPGDRIKVYIVEVKKTTKGPQIIISRSHPGLVKRLFELESPEIQQGIVEIRSIAREPGSRTKMAVFSR
DPNVDPIGACVGYKGSRVQAVVNELKGEKIDIVKWSSKPQEFIMNALSPAKAISVEIVDEKEKVARVIVPDYQLSLAIGK
EGQNARLAAKLTGWKIDIKSESMVKS
>Mature_346_residues
MNAEFIEALNSICEEKGIPKETMFEAIEAALVSAYRKNYGTAQNVKIVMDRETGDVKVYAQKTVVEEVKNDLLEISLEDA
RKINKKYQIGDIVDIEVTPKNFGRIAAQNAKQVVIQRIREAERNVIYEEFLAKETEVVTGIVTRAAKNNVLINLGRVEAI
LTPSEQIPGETFSPGDRIKVYIVEVKKTTKGPQIIISRSHPGLVKRLFELESPEIQQGIVEIRSIAREPGSRTKMAVFSR
DPNVDPIGACVGYKGSRVQAVVNELKGEKIDIVKWSSKPQEFIMNALSPAKAISVEIVDEKEKVARVIVPDYQLSLAIGK
EGQNARLAAKLTGWKIDIKSESMVKS

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=341, Percent_Identity=39.8826979472141, Blast_Score=291, Evalue=4e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 38477; Mature: 38477

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEFIEALNSICEEKGIPKETMFEAIEAALVSAYRKNYGTAQNVKIVMDRETGDVKVYA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEE
QKTVVEEVKNDLLEISLEDARKINKKYQIGDIVDIEVTPKNFGRIAAQNAKQVVIQRIRE
HHHHHHHHHHHHHEEEHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
AERNVIYEEFLAKETEVVTGIVTRAAKNNVLINLGRVEAILTPSEQIPGETFSPGDRIKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHCCCCCCCCCCCEEE
YIVEVKKTTKGPQIIISRSHPGLVKRLFELESPEIQQGIVEIRSIAREPGSRTKMAVFSR
EEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEC
DPNVDPIGACVGYKGSRVQAVVNELKGEKIDIVKWSSKPQEFIMNALSPAKAISVEIVDE
CCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEEECC
KEKVARVIVPDYQLSLAIGKEGQNARLAAKLTGWKIDIKSESMVKS
HHHHHEEECCCEEEEEEECCCCCCCEEEEEEECEEEEECCHHHCCC
>Mature Secondary Structure
MNAEFIEALNSICEEKGIPKETMFEAIEAALVSAYRKNYGTAQNVKIVMDRETGDVKVYA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEE
QKTVVEEVKNDLLEISLEDARKINKKYQIGDIVDIEVTPKNFGRIAAQNAKQVVIQRIRE
HHHHHHHHHHHHHEEEHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
AERNVIYEEFLAKETEVVTGIVTRAAKNNVLINLGRVEAILTPSEQIPGETFSPGDRIKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHCCCCCCCCCCCEEE
YIVEVKKTTKGPQIIISRSHPGLVKRLFELESPEIQQGIVEIRSIAREPGSRTKMAVFSR
EEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEC
DPNVDPIGACVGYKGSRVQAVVNELKGEKIDIVKWSSKPQEFIMNALSPAKAISVEIVDE
CCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEEECC
KEKVARVIVPDYQLSLAIGKEGQNARLAAKLTGWKIDIKSESMVKS
HHHHHEEECCCEEEEEEECCCCCCCEEEEEEECEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]