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The map label for this gene is surE

Identifier: 20807785

GI number: 20807785

Start: 1322720

End: 1323487

Strand: Direct

Name: surE

Synonym: TTE1338

Alternate gene names: 20807785

Gene position: 1322720-1323487 (Clockwise)

Preceding gene: 20807784

Following gene: 20807786

Centisome position: 49.18

GC content: 36.33

Gene sequence:

>768_bases
ATGGGAAAAACCTCAGTACTGCTCACAAATGACGATGGAGTACAGGCAAAGGGGATACTCTACTTAGCAGAATATTTGAA
AGAAAACGGATTTGATGTAGTAGTTGTAGCTCCAGAAAAAGAAAGAAGTGCCATAAGTCATGCAATAACGCTTCACAAAC
CTTTGAGACTAAAACCCGTTAGAGAAGAAGAAAATTTACGCATATATGCGATAAATGGAACCCCTTCCGATTGCGTCAAG
ATGGGGATTGAAGTTGTGATGGAGAAAAATCCTGATATCATAATTTCTGGAATAAACAATGGACTAAACATGGGCACAGA
CATATTGTACTCTGGCACAGTTTCTGCTGCTATAGAGGGGGCACTTTATGGCATACCTGCTCTTGCCGTATCTTTAGAAG
AAGACGGAGACTTTGAAGAACAGCGCATGTACATTTTTTTAAAAAAATTGATAGAGAAAGTCTTGGAAGAAGGATTGCCA
AAAAACACTTTATTAAATGTTAACATCCCAGATTTTAGAAAAGGAATTAATGGAATAAGAATTACAATTTTAGGAAAAAG
AATTTACACAGAGACTTTTCAAAAGAACTACGACCCTAGGGGAAAAGAGTATTATTGGATGGCCGGTAAAATTTCGGAAA
TTGACAATGACGAAAGAACAGATATTGTTTCAGTCAAAAAAGGTTACATTTCGATTACTCCCATTCATTTTGACCTTACA
GACTATGAGGCAGTTAAGAAATTGAGTTCCTGGAAAATTGACATATAA

Upstream 100 bases:

>100_bases
TCCGTAAAAGGGCGCCTTTGTGCGCCTTTTTATTTTATTGCCTCTTTTTTCAGTTTATAATAAAATGGATATGATACAAA
AGATTTGGAGGAGATGAAAA

Downstream 100 bases:

>100_bases
TTTTAAATATTCTAAATGACGCAAGACTTGTATCAAAAATATTCTTGACAGTTGCTATTCATTTTATGAAGGAATTTTTG
TTTTTTTATAGAATATATAT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MGKTSVLLTNDDGVQAKGILYLAEYLKENGFDVVVVAPEKERSAISHAITLHKPLRLKPVREEENLRIYAINGTPSDCVK
MGIEVVMEKNPDIIISGINNGLNMGTDILYSGTVSAAIEGALYGIPALAVSLEEDGDFEEQRMYIFLKKLIEKVLEEGLP
KNTLLNVNIPDFRKGINGIRITILGKRIYTETFQKNYDPRGKEYYWMAGKISEIDNDERTDIVSVKKGYISITPIHFDLT
DYEAVKKLSSWKIDI

Sequences:

>Translated_255_residues
MGKTSVLLTNDDGVQAKGILYLAEYLKENGFDVVVVAPEKERSAISHAITLHKPLRLKPVREEENLRIYAINGTPSDCVK
MGIEVVMEKNPDIIISGINNGLNMGTDILYSGTVSAAIEGALYGIPALAVSLEEDGDFEEQRMYIFLKKLIEKVLEEGLP
KNTLLNVNIPDFRKGINGIRITILGKRIYTETFQKNYDPRGKEYYWMAGKISEIDNDERTDIVSVKKGYISITPIHFDLT
DYEAVKKLSSWKIDI
>Mature_254_residues
GKTSVLLTNDDGVQAKGILYLAEYLKENGFDVVVVAPEKERSAISHAITLHKPLRLKPVREEENLRIYAINGTPSDCVKM
GIEVVMEKNPDIIISGINNGLNMGTDILYSGTVSAAIEGALYGIPALAVSLEEDGDFEEQRMYIFLKKLIEKVLEEGLPK
NTLLNVNIPDFRKGINGIRITILGKRIYTETFQKNYDPRGKEYYWMAGKISEIDNDERTDIVSVKKGYISITPIHFDLTD
YEAVKKLSSWKIDI

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=247, Percent_Identity=42.5101214574899, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_THETN (Q8RA90)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622956.1
- ProteinModelPortal:   Q8RA90
- SMR:   Q8RA90
- GeneID:   997738
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1338
- NMPDR:   fig|273068.3.peg.1276
- HOGENOM:   HBG600532
- OMA:   DCVKMGI
- ProtClustDB:   PRK00346
- BioCyc:   TTEN273068:TTE1338-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28631; Mature: 28500

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTSVLLTNDDGVQAKGILYLAEYLKENGFDVVVVAPEKERSAISHAITLHKPLRLKPV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHEEEECCCCEEECC
REEENLRIYAINGTPSDCVKMGIEVVMEKNPDIIISGINNGLNMGTDILYSGTVSAAIEG
CCCCCEEEEEECCCCHHHHHHHHHEEEECCCCEEEEECCCCCCCCCEEEECCCHHHHHHH
ALYGIPALAVSLEEDGDFEEQRMYIFLKKLIEKVLEEGLPKNTLLNVNIPDFRKGINGIR
HHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCEEE
ITILGKRIYTETFQKNYDPRGKEYYWMAGKISEIDNDERTDIVSVKKGYISITPIHFDLT
EEEEECHHHHHHHHHCCCCCCCEEEEEECEECCCCCCCCCEEEEEECCEEEEEEEEEECC
DYEAVKKLSSWKIDI
CHHHHHHHHCCCCCC
>Mature Secondary Structure 
GKTSVLLTNDDGVQAKGILYLAEYLKENGFDVVVVAPEKERSAISHAITLHKPLRLKPV
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHEEEECCCCEEECC
REEENLRIYAINGTPSDCVKMGIEVVMEKNPDIIISGINNGLNMGTDILYSGTVSAAIEG
CCCCCEEEEEECCCCHHHHHHHHHEEEECCCCEEEEECCCCCCCCCEEEECCCHHHHHHH
ALYGIPALAVSLEEDGDFEEQRMYIFLKKLIEKVLEEGLPKNTLLNVNIPDFRKGINGIR
HHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCEEE
ITILGKRIYTETFQKNYDPRGKEYYWMAGKISEIDNDERTDIVSVKKGYISITPIHFDLT
EEEEECHHHHHHHHHCCCCCCCEEEEEECEECCCCCCCCCEEEEEECCEEEEEEEEEECC
DYEAVKKLSSWKIDI
CHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336