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The map label for this gene is DacC3 [H]

Identifier: 20807777

GI number: 20807777

Start: 1314212

End: 1315354

Strand: Direct

Name: DacC3 [H]

Synonym: TTE1328

Alternate gene names: 20807777

Gene position: 1314212-1315354 (Clockwise)

Preceding gene: 20807776

Following gene: 20807778

Centisome position: 48.87

GC content: 37.01

Gene sequence:

>1143_bases
ATGAAGAAATATTTTTCTTTGCTTTTAATTTTGATGTTTTTTGTCACTTTTTCTAAGGTTTATGGAAGTGATATTCCCTC
TGTTTCTGCGAAGGCTGCTATAGTTATGGACCAGAATACAGGTAGAGTCTTGTATGAAAAGAATGCCCATTTGAAATTAC
CAATGGCCAGCACTACTAAAATAATGACGCTTCTTATAGCTTTAGAGAGAGGAAATTTAAATGACATTGTGACGGTGAGT
CAAAAGGCAGCGAGTGTGGGAGGTTCTTCTATCTGGCTTTCTCCTGGAGAAAAAATAGATATGGAAAGCCTGCTCTACGG
TATCATGTTAAATTCAGGAAATGACGCTGCGACTGCTATAGCGGAACATATTGGAGGAACTGTAGAGAATTTTGTTGAGA
TGATGAATCAAAAGGCGAAAGAGATAGGGGCTTACAATACACATTTTGTAACGCCATCAGGGCTTGACATTGGCATTGAT
GACCATTACACGACTGCTTATGACCTGGCACTCATAACAAGATATGCTTTTTTAAATTATCCTAAATTTGCAGAGATTGT
GTCAACAAAAGAAAAGACGATTCCATGTGAAGGAAAAGAGTGGGACAGGTATTTGAGAAATAAAAATAAGCTTTTGTGGA
TATACGAAGGAGCTGATGGCGTAAAGACAGGATTTACTAATAAAGCTGGAAGGTGCCTTGTTTCTTCGGCTACCAGAGAG
GGGCGGAGGTTTATTGCAGTAGTTTTAAACAGTCCCCCTATGTGGGAAGACTCCATGAAAATTCTAGATTACGCATTTTC
TAGATTCAAGCCTTTTAAGGTATTTGAAAGAAATGATGTGGTGAAAAAGGTAAAAGTGGAAAAAGGAAAAATAGAAGAAA
TTGAAGTTGCAGTAGAAAAAGATTGTATCATACCTGTCTCTGAGGAAGAAATTGGGAAAGTTAATCTAGAGTTTCACATT
CCTGATAAGTTAGAAGCTCCAATCAAAAAAGGGGAAAAAATAGGGCATGTAGTTGTAAAAATAGGGGAGGAGAAAGTCTG
CGAGGTTAATTGCCTTTCTTTTCAAGAAGTGGATAGGCAAGATTTTGTGTACAATTTTAAAAGGATAATAAAAAAGTGGA
TTGAAATTTTTAACCCCTCTTGA

Upstream 100 bases:

>100_bases
GGAAAACGGCAAAAAAACCTCAGAGTCAAATCATTACTACTGGAAATGATGTTTAAAAGTGGGGGAACCCACTTTTTTGT
ATATACAGGGGAGTTGAAAT

Downstream 100 bases:

>100_bases
CTTTTCAAGAGGGGTTTTATTTTGTAATAGTTTTGAACCTCCGAGAATATTTTATTAATGTAAAAATCGGAGGTGAACAA
ATTGGCAAATAGGCTGGAAT

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 5*; PBP-5* [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKKYFSLLLILMFFVTFSKVYGSDIPSVSAKAAIVMDQNTGRVLYEKNAHLKLPMASTTKIMTLLIALERGNLNDIVTVS
QKAASVGGSSIWLSPGEKIDMESLLYGIMLNSGNDAATAIAEHIGGTVENFVEMMNQKAKEIGAYNTHFVTPSGLDIGID
DHYTTAYDLALITRYAFLNYPKFAEIVSTKEKTIPCEGKEWDRYLRNKNKLLWIYEGADGVKTGFTNKAGRCLVSSATRE
GRRFIAVVLNSPPMWEDSMKILDYAFSRFKPFKVFERNDVVKKVKVEKGKIEEIEVAVEKDCIIPVSEEEIGKVNLEFHI
PDKLEAPIKKGEKIGHVVVKIGEEKVCEVNCLSFQEVDRQDFVYNFKRIIKKWIEIFNPS

Sequences:

>Translated_380_residues
MKKYFSLLLILMFFVTFSKVYGSDIPSVSAKAAIVMDQNTGRVLYEKNAHLKLPMASTTKIMTLLIALERGNLNDIVTVS
QKAASVGGSSIWLSPGEKIDMESLLYGIMLNSGNDAATAIAEHIGGTVENFVEMMNQKAKEIGAYNTHFVTPSGLDIGID
DHYTTAYDLALITRYAFLNYPKFAEIVSTKEKTIPCEGKEWDRYLRNKNKLLWIYEGADGVKTGFTNKAGRCLVSSATRE
GRRFIAVVLNSPPMWEDSMKILDYAFSRFKPFKVFERNDVVKKVKVEKGKIEEIEVAVEKDCIIPVSEEEIGKVNLEFHI
PDKLEAPIKKGEKIGHVVVKIGEEKVCEVNCLSFQEVDRQDFVYNFKRIIKKWIEIFNPS
>Mature_380_residues
MKKYFSLLLILMFFVTFSKVYGSDIPSVSAKAAIVMDQNTGRVLYEKNAHLKLPMASTTKIMTLLIALERGNLNDIVTVS
QKAASVGGSSIWLSPGEKIDMESLLYGIMLNSGNDAATAIAEHIGGTVENFVEMMNQKAKEIGAYNTHFVTPSGLDIGID
DHYTTAYDLALITRYAFLNYPKFAEIVSTKEKTIPCEGKEWDRYLRNKNKLLWIYEGADGVKTGFTNKAGRCLVSSATRE
GRRFIAVVLNSPPMWEDSMKILDYAFSRFKPFKVFERNDVVKKVKVEKGKIEEIEVAVEKDCIIPVSEEEIGKVNLEFHI
PDKLEAPIKKGEKIGHVVVKIGEEKVCEVNCLSFQEVDRQDFVYNFKRIIKKWIEIFNPS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex) [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Forespore outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=396, Percent_Identity=30.5555555555556, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI87082022, Length=348, Percent_Identity=30.7471264367816, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1786851, Length=362, Percent_Identity=30.939226519337, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI87082054, Length=275, Percent_Identity=28.3636363636364, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42868; Mature: 42868

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYFSLLLILMFFVTFSKVYGSDIPSVSAKAAIVMDQNTGRVLYEKNAHLKLPMASTTK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCEEEECCCHHHH
IMTLLIALERGNLNDIVTVSQKAASVGGSSIWLSPGEKIDMESLLYGIMLNSGNDAATAI
HHHHHHEECCCCCCCEEEECHHHHHCCCCEEEECCCCCCCHHHHHEEHEEECCCHHHHHH
AEHIGGTVENFVEMMNQKAKEIGAYNTHFVTPSGLDIGIDDHYTTAYDLALITRYAFLNY
HHHHCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCCCCHHHHHHHHHHHHHHCC
PKFAEIVSTKEKTIPCEGKEWDRYLRNKNKLLWIYEGADGVKTGFTNKAGRCLVSSATRE
CHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEHHCCC
GRRFIAVVLNSPPMWEDSMKILDYAFSRFKPFKVFERNDVVKKVKVEKGKIEEIEVAVEK
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCCCCCEEEEEEECC
DCIIPVSEEEIGKVNLEFHIPDKLEAPIKKGEKIGHVVVKIGEEKVCEVNCLSFQEVDRQ
CCEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHCCHH
DFVYNFKRIIKKWIEIFNPS
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKYFSLLLILMFFVTFSKVYGSDIPSVSAKAAIVMDQNTGRVLYEKNAHLKLPMASTTK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCEEEECCCHHHH
IMTLLIALERGNLNDIVTVSQKAASVGGSSIWLSPGEKIDMESLLYGIMLNSGNDAATAI
HHHHHHEECCCCCCCEEEECHHHHHCCCCEEEECCCCCCCHHHHHEEHEEECCCHHHHHH
AEHIGGTVENFVEMMNQKAKEIGAYNTHFVTPSGLDIGIDDHYTTAYDLALITRYAFLNY
HHHHCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCCCCCHHHHHHHHHHHHHHCC
PKFAEIVSTKEKTIPCEGKEWDRYLRNKNKLLWIYEGADGVKTGFTNKAGRCLVSSATRE
CHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEHHCCC
GRRFIAVVLNSPPMWEDSMKILDYAFSRFKPFKVFERNDVVKKVKVEKGKIEEIEVAVEK
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCCCCCEEEEEEECC
DCIIPVSEEEIGKVNLEFHIPDKLEAPIKKGEKIGHVVVKIGEEKVCEVNCLSFQEVDRQ
CCEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHCCHH
DFVYNFKRIIKKWIEIFNPS
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548223; 7934829; 9384377 [H]