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The map label for this gene is HofF [H]

Identifier: 20807713

GI number: 20807713

Start: 1264491

End: 1265702

Strand: Direct

Name: HofF [H]

Synonym: TTE1264

Alternate gene names: 20807713

Gene position: 1264491-1265702 (Clockwise)

Preceding gene: 20807712

Following gene: 20807714

Centisome position: 47.02

GC content: 39.11

Gene sequence:

>1212_bases
ATGCCTTTGTACTTTTACAAAGCAAGGGACATGGGGGGAAACTTAATTACAGGGACTTTGGAGGTAGATTCAAAGTCCCA
GTGCATAGACATATTGAAGGGGAGAAATTATTACATAATTGACATAAAAGAGGAAGTAGTCAAAAAAGACATTCTAGATT
TTAGCTCTTTTAAAAGGGTAAAAGTCAAAGACATTGCAGTTTTTTGCCGCCAGTTTGCTACTTTGATAAATGCAGGAATT
CCTATTCTGACTTCTCTTGCGACAGTGAAAGAACAGGTTAGTAATAAAAAACTCAAAATGGCTTTATCAGAAGTGTACGA
AGAAGTGCAAAAAGGACGTACCCTTTCTGATGCTATGAGAAAGAGAGAAGACGTCTTTCCAATGCTTTTGTATAACATGG
TAGAAGCAGGGGAGGTCAGCGGTACTCTTGACAGGATAATGAATGAGATGGCGGACCACTATGAAAAGGAAAATGACCTC
AATCAGAAAGTAAAATCGGCACTGACATATCCCGCAATTGTGAGCATTGTGGCAGTTTTTGTTGTAGTGTTTTTATTAAC
AAATGTGCTTCCAATATTCGTGGCGATGTTTGAGAATGCAGGAGTAACCCTACCTCTTCCTACGAGAATTTTGCTCTTAA
TTGCTAGCTCAATATCTAACTATTGGTATTTTTACATAGGATTTATTTTCCTTATGGTTTATGGTATATATAATTTTGTG
AAGACTTCTCAGGGAAGGCGAATTTTTGACAGAATGCTTTTGAATATGCCTATTTTTGGACCGCTGAATAAGAAAATTAT
AACTTCCAGGTTTGCAAGGACTTTAGGGACTTTGGTTGGAGCAGGTATACCCCTTGTCAGGGCACTGGAGGTAGTAGAGA
AGGTAGTGGGCAACACAGTAGTTGCAGAGGGCATAAGAAGGGCAGAGGAAGATGTGAAAAAGGGACTACCTTTATCTGAA
CCGTTGAGGAGAATTGGAATTTTCCCTCCCATGGTGATTCAAATGATAAGTGTTGGAGAAAGCTCTGGCGCTCTGGATAC
AATACTTGAGAAGACGGCAAATTTCTTTGACAGAGAAGTTGACACAGCAGTATCCCAGATGACAACTTTGTTAGAGCCGA
TTATAATCCTAATGCTTGCAACAGTGGTAGGCTTCATAGTCGTCTCAATAATAATGCCACTGTTTGAACTATACAATTTC
ATTGGAAGGTAA

Upstream 100 bases:

>100_bases
ATTTTGCACCTTTTAAAATCAGGGGTTATCTCTTTGGAAGATGCTTTAACTTACTGCGTTGACCAGGAGAGCTTTTCACG
CATGATATAGGGGTGATTTT

Downstream 100 bases:

>100_bases
ATTCAAGGGGAAAGGGGGTGAAAAAGGATGGAATGGTTTGTAAAAGCATTAAACAAAGATGAAAGAGGTTTTACACTAAT
TGAGTTGATTGTTGTAATTG

Product: general secretory pathway protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPLYFYKARDMGGNLITGTLEVDSKSQCIDILKGRNYYIIDIKEEVVKKDILDFSSFKRVKVKDIAVFCRQFATLINAGI
PILTSLATVKEQVSNKKLKMALSEVYEEVQKGRTLSDAMRKREDVFPMLLYNMVEAGEVSGTLDRIMNEMADHYEKENDL
NQKVKSALTYPAIVSIVAVFVVVFLLTNVLPIFVAMFENAGVTLPLPTRILLLIASSISNYWYFYIGFIFLMVYGIYNFV
KTSQGRRIFDRMLLNMPIFGPLNKKIITSRFARTLGTLVGAGIPLVRALEVVEKVVGNTVVAEGIRRAEEDVKKGLPLSE
PLRRIGIFPPMVIQMISVGESSGALDTILEKTANFFDREVDTAVSQMTTLLEPIIILMLATVVGFIVVSIIMPLFELYNF
IGR

Sequences:

>Translated_403_residues
MPLYFYKARDMGGNLITGTLEVDSKSQCIDILKGRNYYIIDIKEEVVKKDILDFSSFKRVKVKDIAVFCRQFATLINAGI
PILTSLATVKEQVSNKKLKMALSEVYEEVQKGRTLSDAMRKREDVFPMLLYNMVEAGEVSGTLDRIMNEMADHYEKENDL
NQKVKSALTYPAIVSIVAVFVVVFLLTNVLPIFVAMFENAGVTLPLPTRILLLIASSISNYWYFYIGFIFLMVYGIYNFV
KTSQGRRIFDRMLLNMPIFGPLNKKIITSRFARTLGTLVGAGIPLVRALEVVEKVVGNTVVAEGIRRAEEDVKKGLPLSE
PLRRIGIFPPMVIQMISVGESSGALDTILEKTANFFDREVDTAVSQMTTLLEPIIILMLATVVGFIVVSIIMPLFELYNF
IGR
>Mature_402_residues
PLYFYKARDMGGNLITGTLEVDSKSQCIDILKGRNYYIIDIKEEVVKKDILDFSSFKRVKVKDIAVFCRQFATLINAGIP
ILTSLATVKEQVSNKKLKMALSEVYEEVQKGRTLSDAMRKREDVFPMLLYNMVEAGEVSGTLDRIMNEMADHYEKENDLN
QKVKSALTYPAIVSIVAVFVVVFLLTNVLPIFVAMFENAGVTLPLPTRILLLIASSISNYWYFYIGFIFLMVYGIYNFVK
TSQGRRIFDRMLLNMPIFGPLNKKIITSRFARTLGTLVGAGIPLVRALEVVEKVVGNTVVAEGIRRAEEDVKKGLPLSEP
LRRIGIFPPMVIQMISVGESSGALDTILEKTANFFDREVDTAVSQMTTLLEPIIILMLATVVGFIVVSIIMPLFELYNFI
GR

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=398, Percent_Identity=30.4020100502513, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1786295, Length=400, Percent_Identity=25.5, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45293; Mature: 45162

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLYFYKARDMGGNLITGTLEVDSKSQCIDILKGRNYYIIDIKEEVVKKDILDFSSFKRV
CCEEEEECCCCCCCEEEEEEEECCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCHH
KVKDIAVFCRQFATLINAGIPILTSLATVKEQVSNKKLKMALSEVYEEVQKGRTLSDAMR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KREDVFPMLLYNMVEAGEVSGTLDRIMNEMADHYEKENDLNQKVKSALTYPAIVSIVAVF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVFLLTNVLPIFVAMFENAGVTLPLPTRILLLIASSISNYWYFYIGFIFLMVYGIYNFV
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTSQGRRIFDRMLLNMPIFGPLNKKIITSRFARTLGTLVGAGIPLVRALEVVEKVVGNTV
HHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
VAEGIRRAEEDVKKGLPLSEPLRRIGIFPPMVIQMISVGESSGALDTILEKTANFFDREV
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
DTAVSQMTTLLEPIIILMLATVVGFIVVSIIMPLFELYNFIGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLYFYKARDMGGNLITGTLEVDSKSQCIDILKGRNYYIIDIKEEVVKKDILDFSSFKRV
CEEEEECCCCCCCEEEEEEEECCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCHH
KVKDIAVFCRQFATLINAGIPILTSLATVKEQVSNKKLKMALSEVYEEVQKGRTLSDAMR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KREDVFPMLLYNMVEAGEVSGTLDRIMNEMADHYEKENDLNQKVKSALTYPAIVSIVAVF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVFLLTNVLPIFVAMFENAGVTLPLPTRILLLIASSISNYWYFYIGFIFLMVYGIYNFV
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTSQGRRIFDRMLLNMPIFGPLNKKIITSRFARTLGTLVGAGIPLVRALEVVEKVVGNTV
HHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
VAEGIRRAEEDVKKGLPLSEPLRRIGIFPPMVIQMISVGESSGALDTILEKTANFFDREV
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
DTAVSQMTTLLEPIIILMLATVVGFIVVSIIMPLFELYNFIGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]