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The map label for this gene is cymR [H]

Identifier: 20807692

GI number: 20807692

Start: 1243736

End: 1244185

Strand: Direct

Name: cymR [H]

Synonym: TTE1242

Alternate gene names: 20807692

Gene position: 1243736-1244185 (Clockwise)

Preceding gene: 20807691

Following gene: 20807693

Centisome position: 46.25

GC content: 41.33

Gene sequence:

>450_bases
ATGAAGCTTTCTACAAAGGGAAGATACGGGATTCAAGCTATGTTTGAATTGGCCCTATATTACGGGGAAGGACCTATCTC
TTTAAAGACTATCGCAGAAAATGAAGGGCTTTCTGAACATTATCTGGAACAGCTTATGGCAATTTTGAGAAAAGCAGACC
TTGTAAAAAGCGTAAGAGGTGCTCAAGGAGGGTATATGCTGGCAGCTCCGCCGGATAAAATAACTGTAGGCGATGTGATA
AGGACTCTAGAAGGTTCTCTTGCCCCTGCAGATTGTGTAGTGGAAGACACTCCTTTTGAATGCAGCAGAGCAGGAGGCTG
TCCTACAAAGCTGGTTATGGAGAGAATAAGAGACAGCATAAATAAAGTTATAGATTCTATCACTTTGCAAGACATGGTGG
AAGACTACAGAAGGCTTAATCAAAAAAGCGCTTTTATGTACTACATTTAA

Upstream 100 bases:

>100_bases
AGAGGCGTAAGCCTCTTTTTATGTTGACAATAACTTTGTTACATGGTATGCTTTTTATTGAAATCCGGGTGATATAGTAG
GAATTCAGGGGTGAGGAACT

Downstream 100 bases:

>100_bases
AGCTTTGAAAAGGAGGAATTTTTACTTTTCATGGAGGTTAACAACAGAGTTGTAGTTGGAATGAGCGGAGGAGTAGATAG
TTCAGTCACTGCATACCTTT

Product: transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLMAILRKADLVKSVRGAQGGYMLAAPPDKITVGDVI
RTLEGSLAPADCVVEDTPFECSRAGGCPTKLVMERIRDSINKVIDSITLQDMVEDYRRLNQKSAFMYYI

Sequences:

>Translated_149_residues
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLMAILRKADLVKSVRGAQGGYMLAAPPDKITVGDVI
RTLEGSLAPADCVVEDTPFECSRAGGCPTKLVMERIRDSINKVIDSITLQDMVEDYRRLNQKSAFMYYI
>Mature_149_residues
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLMAILRKADLVKSVRGAQGGYMLAAPPDKITVGDVI
RTLEGSLAPADCVVEDTPFECSRAGGCPTKLVMERIRDSINKVIDSITLQDMVEDYRRLNQKSAFMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=140, Percent_Identity=36.4285714285714, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16574; Mature: 16574

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLMAILRKADLVKSVRG
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AQGGYMLAAPPDKITVGDVIRTLEGSLAPADCVVEDTPFECSRAGGCPTKLVMERIRDSI
CCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHH
NKVIDSITLQDMVEDYRRLNQKSAFMYYI
HHHHHHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MKLSTKGRYGIQAMFELALYYGEGPISLKTIAENEGLSEHYLEQLMAILRKADLVKSVRG
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AQGGYMLAAPPDKITVGDVIRTLEGSLAPADCVVEDTPFECSRAGGCPTKLVMERIRDSI
CCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHH
NKVIDSITLQDMVEDYRRLNQKSAFMYYI
HHHHHHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]