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The map label for this gene is mutL [H]

Identifier: 20807691

GI number: 20807691

Start: 1241222

End: 1242565

Strand: Direct

Name: mutL [H]

Synonym: TTE1239

Alternate gene names: 20807691

Gene position: 1241222-1242565 (Clockwise)

Preceding gene: 20807690

Following gene: 20807692

Centisome position: 46.15

GC content: 41.22

Gene sequence:

>1344_bases
ATGAAAAGGACAGTTGATGTTCTGGTAGCTGAGATTGGAAGTACAACTACAACTGTAAATGCTTTTAACTTAGAGGGCAC
ACCGATCTTTCTAGGGCAGGGCATGGCACCTACTACTGTGCTAGAAGGAGATGTAAATGTTGGGCTCAAGGCTGCCATTG
AAGATTTGAAAGGTAAAATAGGGGATTTTGAGTACAAAGAAATGCTCGCCTGTAGTAGCGCTGCAGGCGGGCTTAAAATG
ACTGTCCACGGTCTTGTCTATGACATGACTGTAAGAGCAGCAAAAGAAGCGGCTTTGGGGGCAGGTGCCAATATAAAGCT
TATCACTGCAGGAAAATTGAGAAGAACCGATTTGGAAAAAATAAAAGAGATAAAACCTAATATAATACTTTTGGCAGGTG
GAGTGGATTACGGAGACAGAGAGACAGCCCTTTATAATGGCGAAAAGTTAGCAGAACTGAAACTGAACGTGCCTGTGATA
TACGCTGGAAACATAGAGAACAGGGAAGAAATAGCCTATATATTCAAGGAAGCAGGTCAAGAAGTGTACATTGTAGACAA
TGTATATCCTTCTATTGATAAACTGAATGTTGAACCCACGAGAAAAATGATTCAACAGGTGTTTGAAAAGCACATCATCA
CGGCTCCGGGGATGAGCAGGGTAAAAGAATTGGTCACAGGTAATATCATTCCGACTCCTGGAGCAGTGATGGAAGCCTGC
ATACTGCTTTACAATGAAATAGGAGATCTTATGGCATTAGACATAGGAGGAGCCACTACAGATGTCCACTCTGTTACAGA
AGGAAGTGAAGAGATACAAAAGATGACAGTAAATCCGGAGCCATTGGCCAAAAGGACTGTAGAAGGGGATTTAGGGGTAT
TTGTAAATTCCAGAAATCTTTTTGAACTCTGGGGAGAGGAAGTTTATAAAAAATTTGCCAATGCTGAAGAACTTATAAAA
AACATAAAGCCAGTTCCAACAACAGATGAAGAGAGGGAATTTGTTCTCTTTCTTGCAGCTAAAGCTGTAGAAATAGCAGT
AAAGCGCCATGCTGGCAAAATGGTCAGCTATTTTGGACCCACTGGAAAGAGCTTTTACGTTGAGGGAAGAGATTTGACAG
CAGTAAAGTGGATTATAGGAACTGGAGGAGTCTTTACAAGACTTGAGGGTTCAGAGGAATTGCTCAAAAACATAAATGAC
AAAGCTCCTGGGAAGGAGCTCTATCCTCCTTCTTCAGCAAAAGTTTTAATTGACAGAGATTATATCATGGCGGCTTGCGG
AGTTTTATCTAAAAAATACCCTGAAGAGGCTTTGAGACTGCTGAAAAATAGCCTTGGAATTTAA

Upstream 100 bases:

>100_bases
GATTTGGCTAAAAGCGTAGGATTTGATGCCGGATTTGGCAGGGGCACAAAAGGAAATCAGGTAGCAAGCTTTTTAGTTAA
AAGGAGAAGGGAAATGGAAA

Downstream 100 bases:

>100_bases
AAGTGAGGGAAGATAGATGTATCCTTTATTGAGAATAAATTTAGAAAAGCTTCGCCACAACGCCCATATTATTGTTGAAC
TGTGTAGAAAAAGAAATATA

Product: methylaspartate mutase

Products: L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKRTVDVLVAEIGSTTTTVNAFNLEGTPIFLGQGMAPTTVLEGDVNVGLKAAIEDLKGKIGDFEYKEMLACSSAAGGLKM
TVHGLVYDMTVRAAKEAALGAGANIKLITAGKLRRTDLEKIKEIKPNIILLAGGVDYGDRETALYNGEKLAELKLNVPVI
YAGNIENREEIAYIFKEAGQEVYIVDNVYPSIDKLNVEPTRKMIQQVFEKHIITAPGMSRVKELVTGNIIPTPGAVMEAC
ILLYNEIGDLMALDIGGATTDVHSVTEGSEEIQKMTVNPEPLAKRTVEGDLGVFVNSRNLFELWGEEVYKKFANAEELIK
NIKPVPTTDEEREFVLFLAAKAVEIAVKRHAGKMVSYFGPTGKSFYVEGRDLTAVKWIIGTGGVFTRLEGSEELLKNIND
KAPGKELYPPSSAKVLIDRDYIMAACGVLSKKYPEEALRLLKNSLGI

Sequences:

>Translated_447_residues
MKRTVDVLVAEIGSTTTTVNAFNLEGTPIFLGQGMAPTTVLEGDVNVGLKAAIEDLKGKIGDFEYKEMLACSSAAGGLKM
TVHGLVYDMTVRAAKEAALGAGANIKLITAGKLRRTDLEKIKEIKPNIILLAGGVDYGDRETALYNGEKLAELKLNVPVI
YAGNIENREEIAYIFKEAGQEVYIVDNVYPSIDKLNVEPTRKMIQQVFEKHIITAPGMSRVKELVTGNIIPTPGAVMEAC
ILLYNEIGDLMALDIGGATTDVHSVTEGSEEIQKMTVNPEPLAKRTVEGDLGVFVNSRNLFELWGEEVYKKFANAEELIK
NIKPVPTTDEEREFVLFLAAKAVEIAVKRHAGKMVSYFGPTGKSFYVEGRDLTAVKWIIGTGGVFTRLEGSEELLKNIND
KAPGKELYPPSSAKVLIDRDYIMAACGVLSKKYPEEALRLLKNSLGI
>Mature_447_residues
MKRTVDVLVAEIGSTTTTVNAFNLEGTPIFLGQGMAPTTVLEGDVNVGLKAAIEDLKGKIGDFEYKEMLACSSAAGGLKM
TVHGLVYDMTVRAAKEAALGAGANIKLITAGKLRRTDLEKIKEIKPNIILLAGGVDYGDRETALYNGEKLAELKLNVPVI
YAGNIENREEIAYIFKEAGQEVYIVDNVYPSIDKLNVEPTRKMIQQVFEKHIITAPGMSRVKELVTGNIIPTPGAVMEAC
ILLYNEIGDLMALDIGGATTDVHSVTEGSEEIQKMTVNPEPLAKRTVEGDLGVFVNSRNLFELWGEEVYKKFANAEELIK
NIKPVPTTDEEREFVLFLAAKAVEIAVKRHAGKMVSYFGPTGKSFYVEGRDLTAVKWIIGTGGVFTRLEGSEELLKNIND
KAPGKELYPPSSAKVLIDRDYIMAACGVLSKKYPEEALRLLKNSLGI

Specific function: May play a role in glutamate fermentation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006230
- InterPro:   IPR002821 [H]

Pfam domain/function: PF01968 Hydantoinase_A [H]

EC number: 5.4.99.1

Molecular weight: Translated: 48749; Mature: 48749

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTVDVLVAEIGSTTTTVNAFNLEGTPIFLGQGMAPTTVLEGDVNVGLKAAIEDLKGKI
CCCHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHCCCC
GDFEYKEMLACSSAAGGLKMTVHGLVYDMTVRAAKEAALGAGANIKLITAGKLRRTDLEK
CCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
IKEIKPNIILLAGGVDYGDRETALYNGEKLAELKLNVPVIYAGNIENREEIAYIFKEAGQ
HHHCCCCEEEEECCCCCCCCCCEEECCCEEEEEEECCCEEEECCCCCHHHHHHHHHHCCC
EVYIVDNVYPSIDKLNVEPTRKMIQQVFEKHIITAPGMSRVKELVTGNIIPTPGAVMEAC
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
ILLYNEIGDLMALDIGGATTDVHSVTEGSEEIQKMTVNPEPLAKRTVEGDLGVFVNSRNL
HHHHHHHCCEEEEECCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHCCCCCCEEEECCCHH
FELWGEEVYKKFANAEELIKNIKPVPTTDEEREFVLFLAAKAVEIAVKRHAGKMVSYFGP
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEECCC
TGKSFYVEGRDLTAVKWIIGTGGVFTRLEGSEELLKNINDKAPGKELYPPSSAKVLIDRD
CCCEEEEECCCEEEEEEEEECCCEEEEECCHHHHHHCCCCCCCCCCCCCCCCCEEEEECH
YIMAACGVLSKKYPEEALRLLKNSLGI
HHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRTVDVLVAEIGSTTTTVNAFNLEGTPIFLGQGMAPTTVLEGDVNVGLKAAIEDLKGKI
CCCHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHCCCC
GDFEYKEMLACSSAAGGLKMTVHGLVYDMTVRAAKEAALGAGANIKLITAGKLRRTDLEK
CCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
IKEIKPNIILLAGGVDYGDRETALYNGEKLAELKLNVPVIYAGNIENREEIAYIFKEAGQ
HHHCCCCEEEEECCCCCCCCCCEEECCCEEEEEEECCCEEEECCCCCHHHHHHHHHHCCC
EVYIVDNVYPSIDKLNVEPTRKMIQQVFEKHIITAPGMSRVKELVTGNIIPTPGAVMEAC
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
ILLYNEIGDLMALDIGGATTDVHSVTEGSEEIQKMTVNPEPLAKRTVEGDLGVFVNSRNL
HHHHHHHCCEEEEECCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHCCCCCCEEEECCCHH
FELWGEEVYKKFANAEELIKNIKPVPTTDEEREFVLFLAAKAVEIAVKRHAGKMVSYFGP
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEECCC
TGKSFYVEGRDLTAVKWIIGTGGVFTRLEGSEELLKNINDKAPGKELYPPSSAKVLIDRD
CCCEEEEECCCEEEEEEEEECCCEEEEECCHHHHHHCCCCCCCCCCCCCCCCCEEEEECH
YIMAACGVLSKKYPEEALRLLKNSLGI
HHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-threo-3-methylaspartate

Specific reaction: L-threo-3-methylaspartate = L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428631 [H]