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The map label for this gene is prmA

Identifier: 20807438

GI number: 20807438

Start: 961974

End: 962903

Strand: Direct

Name: prmA

Synonym: TTE0957

Alternate gene names: 20807438

Gene position: 961974-962903 (Clockwise)

Preceding gene: 20807437

Following gene: 20807439

Centisome position: 35.77

GC content: 38.82

Gene sequence:

>930_bases
ATGAAATGGTTAGAAATACAGGTTACAACTTCACAGGAAGCAGAAGAGGCTGTCACAGGCATTTTGTACGATTTAGGAGC
AGGCGGAGTGGTTATAAAAAATCCTAACGATGTAAAAGAACTGGCACAGACTAGTGAGTGGGATTATTTTGACCCTTCCC
TTCTAGAAGAAGGAGAAGAGGTAAAGATTTCGGCCTATTTTCTAATCACTACTGATATAACAGACAAAGTAAATTTTTTA
AAAGAGAGGATTTGGGAACTCAAGTCTTTTGGGATAAATGTGGGAAATGTCAAGGTAGAGGTTTCTGAGGTGGACGAAGA
AGACTGGGCAGACAGCTGGAAGAAGTATTACAAGCCTTTAAAAGTTGGCAAAAGGATTGTCGTAAGGCCTTTATGGGAAG
AATACAGCCCTAAAGAGGGAGAAATAGTTATAGACCTTGACCCTGGAATGGCTTTTGGCACGGGTACTCATGAGACTACA
AAGATGTGCCTCCAATTTTTAGAAGACATTGTAAAGCCAGGAGCAATTGTGTTTGACGTCGGTTGCGGTTCAGGTATACT
TTCTATCGCCGCTTCTAAATTGGGAGCATCTTATGTGTACGGAGCGGACGTAGATGAAATGGCGGTGAAAATAGCTAGAG
AAAATGTAAAATTAAATGGTCTTGAAAATGTGGAGATTTTTCAAAGCGACCTCCTTAAAAATTTTAGAGGAAAGGCAGAT
GTGATAGTAGCTAACATTATTGCAGATGCAATAATTAGGCTTATTCCTGATGTTTTGCCTCATCTTAAAGAGGAAGGTTT
ATTTTTAGCAAGCGGCATCATTAAAGACAGGTTTGAAGAAGTGAAAGAAAGAGCAGAGGAATTTTTTGAAATAATTGATA
TGAAAGAAGAAAAAGAGTGGTTGAGCATATTGATGAAGAAAAAGGGATAG

Upstream 100 bases:

>100_bases
AGATTAGAAGGCGAGAATACAGCAGAGCACAAGTCCTTTTTTCAGAGAATGAGGGACGCTTTTGGAGGAAGTTAAAATTT
AGAAAAAGGTGTTGAAGGAA

Downstream 100 bases:

>100_bases
AAATGAGGAAGATCTTTGTTGAAAAGGGCAAAATAAAGGGAAAATTTGCCTATGTAGATGGGAAGGATTTTCACCATCTC
ATTCATGTATTAAGGTATAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKWLEIQVTTSQEAEEAVTGILYDLGAGGVVIKNPNDVKELAQTSEWDYFDPSLLEEGEEVKISAYFLITTDITDKVNFL
KERIWELKSFGINVGNVKVEVSEVDEEDWADSWKKYYKPLKVGKRIVVRPLWEEYSPKEGEIVIDLDPGMAFGTGTHETT
KMCLQFLEDIVKPGAIVFDVGCGSGILSIAASKLGASYVYGADVDEMAVKIARENVKLNGLENVEIFQSDLLKNFRGKAD
VIVANIIADAIIRLIPDVLPHLKEEGLFLASGIIKDRFEEVKERAEEFFEIIDMKEEKEWLSILMKKKG

Sequences:

>Translated_309_residues
MKWLEIQVTTSQEAEEAVTGILYDLGAGGVVIKNPNDVKELAQTSEWDYFDPSLLEEGEEVKISAYFLITTDITDKVNFL
KERIWELKSFGINVGNVKVEVSEVDEEDWADSWKKYYKPLKVGKRIVVRPLWEEYSPKEGEIVIDLDPGMAFGTGTHETT
KMCLQFLEDIVKPGAIVFDVGCGSGILSIAASKLGASYVYGADVDEMAVKIARENVKLNGLENVEIFQSDLLKNFRGKAD
VIVANIIADAIIRLIPDVLPHLKEEGLFLASGIIKDRFEEVKERAEEFFEIIDMKEEKEWLSILMKKKG
>Mature_309_residues
MKWLEIQVTTSQEAEEAVTGILYDLGAGGVVIKNPNDVKELAQTSEWDYFDPSLLEEGEEVKISAYFLITTDITDKVNFL
KERIWELKSFGINVGNVKVEVSEVDEEDWADSWKKYYKPLKVGKRIVVRPLWEEYSPKEGEIVIDLDPGMAFGTGTHETT
KMCLQFLEDIVKPGAIVFDVGCGSGILSIAASKLGASYVYGADVDEMAVKIARENVKLNGLENVEIFQSDLLKNFRGKAD
VIVANIIADAIIRLIPDVLPHLKEEGLFLASGIIKDRFEEVKERAEEFFEIIDMKEEKEWLSILMKKKG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=314, Percent_Identity=31.8471337579618, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_THETN (Q8RB66)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622609.1
- ProteinModelPortal:   Q8RB66
- SMR:   Q8RB66
- GeneID:   995845
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0957
- NMPDR:   fig|273068.3.peg.381
- HOGENOM:   HBG584653
- OMA:   AVDIEPW
- ProtClustDB:   PRK00517
- BioCyc:   TTEN273068:TTE0957-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34776; Mature: 34776

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWLEIQVTTSQEAEEAVTGILYDLGAGGVVIKNPNDVKELAQTSEWDYFDPSLLEEGEE
CCEEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCHHHHCCCCE
VKISAYFLITTDITDKVNFLKERIWELKSFGINVGNVKVEVSEVDEEDWADSWKKYYKPL
EEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
KVGKRIVVRPLWEEYSPKEGEIVIDLDPGMAFGTGTHETTKMCLQFLEDIVKPGAIVFDV
HHCCEEEEEEHHHHCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEC
GCGSGILSIAASKLGASYVYGADVDEMAVKIARENVKLNGLENVEIFQSDLLKNFRGKAD
CCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCHH
VIVANIIADAIIRLIPDVLPHLKEEGLFLASGIIKDRFEEVKERAEEFFEIIDMKEEKEW
HHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LSILMKKKG
HHHHHHCCC
>Mature Secondary Structure
MKWLEIQVTTSQEAEEAVTGILYDLGAGGVVIKNPNDVKELAQTSEWDYFDPSLLEEGEE
CCEEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCHHHHCCCCE
VKISAYFLITTDITDKVNFLKERIWELKSFGINVGNVKVEVSEVDEEDWADSWKKYYKPL
EEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
KVGKRIVVRPLWEEYSPKEGEIVIDLDPGMAFGTGTHETTKMCLQFLEDIVKPGAIVFDV
HHCCEEEEEEHHHHCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEC
GCGSGILSIAASKLGASYVYGADVDEMAVKIARENVKLNGLENVEIFQSDLLKNFRGKAD
CCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCHH
VIVANIIADAIIRLIPDVLPHLKEEGLFLASGIIKDRFEEVKERAEEFFEIIDMKEEKEW
HHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LSILMKKKG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336