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The map label for this gene is dapA [H]

Identifier: 20807314

GI number: 20807314

Start: 838670

End: 839563

Strand: Reverse

Name: dapA [H]

Synonym: TTE0832

Alternate gene names: 20807314

Gene position: 839563-838670 (Counterclockwise)

Preceding gene: 20807315

Following gene: 20807313

Centisome position: 31.22

GC content: 40.49

Gene sequence:

>894_bases
ATGCCTGTATTTAAAGGTTCATGTGTGGCCATAGTGACCCCTTTTACTGAAAATGGAGTGAATTTTGACAAACTTGGCGA
ATTGATTGAATGGCATATAAAAGAAGGAACAGATGCAATCCTCATATGCGGAACTACGGGTGAAGCTTCCACAATGACTG
ATGAAGAGCAAAAGGAAGCCATAAAATTTACAGTAGAAAAAGTGGCAAAGAGAATACCAGTTATTGCAGGAACCGGTTCG
AACAACACTGCTCATGCGATTGAACTCAGCGAATACGCACAATCAGTCGGAGCAGATGCTCTTTTGGTCATCACCCCTTA
TTACAACAAAACAACACAAAAAGGATTGGTAGCTCATTTCACTGAAATAGCACGTCACGTAGATATACCTATTATAATCT
ACAACGTGCCCAGCAGAACATCTTTAAACATGTTGCCTGAGACGTACTTAGAAGTCAAGAAAAAAGCAGAAAATGTGGTG
GGAGTGAAAGAAGCAAGTGGAGACATATCTCAGATCGCTGAAATCGCCCGCATAATGGGCAAGTCTTTTGAAATATACTC
AGGAAATGATGACCAGGTAATACCAATCATGTCTTTAGGAGGTCTTGGAGTGATCTCCGTAACAGCAAACATAATTCCTG
CAAAAATCCATGAGATGACGACAGCATACCTCAATGGAGACATTGAAAAAGCAAGAGATATGCAACTAGAACTAAATCCT
TTAAATAAAGCCCTTTTCATAGAGACAAATCCAATACCTGTAAAAACAGCCATGAACCTCATGGGCTTTGGAGTGGGTCC
TCTTCGCCTGCCGCTTGTTGAAATGAGCGAGAAAAACCTTGAATACCTAAAGTCAGTTTTAAGGCAGTATGGCCTTTTAA
AGGAGGAAAATTGA

Upstream 100 bases:

>100_bases
ACATGTGGATTGTGGCGGATAACATAAGAAAAGGTGCGGCGACAAATGCCGTGCAGATTGCTGAACTTGTAATCAAAAAT
ATGTGAAAGGAGAATGGAGC

Downstream 100 bases:

>100_bases
TGATAAGGCTAATAATCCACGGCTGCAATGGAAAAATGGGAAAAGTAGTAGCAAAGCTGGCAAAAGAAAATCCTGAATTT
GAAGTAGTAGCAGGAGTTGA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPVFKGSCVAIVTPFTENGVNFDKLGELIEWHIKEGTDAILICGTTGEASTMTDEEQKEAIKFTVEKVAKRIPVIAGTGS
NNTAHAIELSEYAQSVGADALLVITPYYNKTTQKGLVAHFTEIARHVDIPIIIYNVPSRTSLNMLPETYLEVKKKAENVV
GVKEASGDISQIAEIARIMGKSFEIYSGNDDQVIPIMSLGGLGVISVTANIIPAKIHEMTTAYLNGDIEKARDMQLELNP
LNKALFIETNPIPVKTAMNLMGFGVGPLRLPLVEMSEKNLEYLKSVLRQYGLLKEEN

Sequences:

>Translated_297_residues
MPVFKGSCVAIVTPFTENGVNFDKLGELIEWHIKEGTDAILICGTTGEASTMTDEEQKEAIKFTVEKVAKRIPVIAGTGS
NNTAHAIELSEYAQSVGADALLVITPYYNKTTQKGLVAHFTEIARHVDIPIIIYNVPSRTSLNMLPETYLEVKKKAENVV
GVKEASGDISQIAEIARIMGKSFEIYSGNDDQVIPIMSLGGLGVISVTANIIPAKIHEMTTAYLNGDIEKARDMQLELNP
LNKALFIETNPIPVKTAMNLMGFGVGPLRLPLVEMSEKNLEYLKSVLRQYGLLKEEN
>Mature_296_residues
PVFKGSCVAIVTPFTENGVNFDKLGELIEWHIKEGTDAILICGTTGEASTMTDEEQKEAIKFTVEKVAKRIPVIAGTGSN
NTAHAIELSEYAQSVGADALLVITPYYNKTTQKGLVAHFTEIARHVDIPIIIYNVPSRTSLNMLPETYLEVKKKAENVVG
VKEASGDISQIAEIARIMGKSFEIYSGNDDQVIPIMSLGGLGVISVTANIIPAKIHEMTTAYLNGDIEKARDMQLELNPL
NKALFIETNPIPVKTAMNLMGFGVGPLRLPLVEMSEKNLEYLKSVLRQYGLLKEEN

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=290, Percent_Identity=28.2758620689655, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI13540533, Length=298, Percent_Identity=26.1744966442953, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788823, Length=293, Percent_Identity=41.9795221843003, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1786463, Length=234, Percent_Identity=32.4786324786325, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87082415, Length=300, Percent_Identity=30.6666666666667, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789620, Length=290, Percent_Identity=27.2413793103448, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32496; Mature: 32365

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFKGSCVAIVTPFTENGVNFDKLGELIEWHIKEGTDAILICGTTGEASTMTDEEQKEA
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
IKFTVEKVAKRIPVIAGTGSNNTAHAIELSEYAQSVGADALLVITPYYNKTTQKGLVAHF
HHHHHHHHHHHCCEEEECCCCCCEEEEEHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
TEIARHVDIPIIIYNVPSRTSLNMLPETYLEVKKKAENVVGVKEASGDISQIAEIARIMG
HHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCEEHHCCCCHHHHHHHHHHHC
KSFEIYSGNDDQVIPIMSLGGLGVISVTANIIPAKIHEMTTAYLNGDIEKARDMQLELNP
CCEEEEECCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEC
LNKALFIETNPIPVKTAMNLMGFGVGPLRLPLVEMSEKNLEYLKSVLRQYGLLKEEN
CCEEEEEECCCCCHHHHHHHHHCCCCCCEECHHHHCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PVFKGSCVAIVTPFTENGVNFDKLGELIEWHIKEGTDAILICGTTGEASTMTDEEQKEA
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
IKFTVEKVAKRIPVIAGTGSNNTAHAIELSEYAQSVGADALLVITPYYNKTTQKGLVAHF
HHHHHHHHHHHCCEEEECCCCCCEEEEEHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
TEIARHVDIPIIIYNVPSRTSLNMLPETYLEVKKKAENVVGVKEASGDISQIAEIARIMG
HHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCEEHHCCCCHHHHHHHHHHHC
KSFEIYSGNDDQVIPIMSLGGLGVISVTANIIPAKIHEMTTAYLNGDIEKARDMQLELNP
CCEEEEECCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEC
LNKALFIETNPIPVKTAMNLMGFGVGPLRLPLVEMSEKNLEYLKSVLRQYGLLKEEN
CCEEEEEECCCCCHHHHHHHHHCCCCCCEECHHHHCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA