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The map label for this gene is DapB

Identifier: 20807313

GI number: 20807313

Start: 837918

End: 838673

Strand: Reverse

Name: DapB

Synonym: TTE0831

Alternate gene names: 20807313

Gene position: 838673-837918 (Counterclockwise)

Preceding gene: 20807314

Following gene: 20807312

Centisome position: 31.18

GC content: 38.76

Gene sequence:

>756_bases
TTGATGATAAGGCTAATAATCCACGGCTGCAATGGAAAAATGGGAAAAGTAGTAGCAAAGCTGGCAAAAGAAAATCCTGA
ATTTGAAGTAGTAGCAGGAGTTGACAAAAACACCTTCCCTCTAGACTTCCCTGTATACTCTGACCTAAAAGAAGTAAAAG
AAGAAGCAGATGTAGTCATAGACTTCTCCTATCACGAAGCCATTCCAAATTTAGTAAAAGAAGCTGCAAAAAGAAAAATT
CCTGTGGTCATTGCCACAACAGGCTTGAGCGAAGAAGAATTAAAAACAGTGGAAGAAGCTTCAAAAGAGATACCTATCTT
CAGATCTGCCAACATGTCTTTGGGCATAAACGTGCTGATAAGCCTTGTAAAAGAAGCAGCAAAAGTTTTAGAAGGGTTTG
ATATAGAAATCGTAGAAAAGCATCACAACATGAAAAAAGACGCGCCGAGCGGCACAGCACTTATGATAGCAGATGCAATA
AATCAGGTTCTTCCTGAGAAAAGAGAATACGTGTATGGAAGGTACACAAAAACAGAACAAAGAAAGCCAAATGAGATAGG
AATACATGCAGTAAGAGGAGGGACAATAGTAGGAGAACACGATGTAATCTTCGCAGGACCCAATGAAGTAATAACAATTT
CTCACTCTGCCCAGTCAAGGGAAGTCTTTGGATATGGAGCTTTAAAAGCAGCTAAATTTTTAATAGGTCAAAAACCTGGC
TTATATACAATGGAAGACCTTGTAAAGAAAGGATGA

Upstream 100 bases:

>100_bases
GAGTGGGTCCTCTTCGCCTGCCGCTTGTTGAAATGAGCGAGAAAAACCTTGAATACCTAAAGTCAGTTTTAAGGCAGTAT
GGCCTTTTAAAGGAGGAAAA

Downstream 100 bases:

>100_bases
TAAACTTGAACACAAATGATAACCTGACGAACGCCTATGAAATTGCAAGATACATCAAAGAAGCAAAAAAATCCACTCCA
GTAAAGGCATATGTACAGGG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MMIRLIIHGCNGKMGKVVAKLAKENPEFEVVAGVDKNTFPLDFPVYSDLKEVKEEADVVIDFSYHEAIPNLVKEAAKRKI
PVVIATTGLSEEELKTVEEASKEIPIFRSANMSLGINVLISLVKEAAKVLEGFDIEIVEKHHNMKKDAPSGTALMIADAI
NQVLPEKREYVYGRYTKTEQRKPNEIGIHAVRGGTIVGEHDVIFAGPNEVITISHSAQSREVFGYGALKAAKFLIGQKPG
LYTMEDLVKKG

Sequences:

>Translated_251_residues
MMIRLIIHGCNGKMGKVVAKLAKENPEFEVVAGVDKNTFPLDFPVYSDLKEVKEEADVVIDFSYHEAIPNLVKEAAKRKI
PVVIATTGLSEEELKTVEEASKEIPIFRSANMSLGINVLISLVKEAAKVLEGFDIEIVEKHHNMKKDAPSGTALMIADAI
NQVLPEKREYVYGRYTKTEQRKPNEIGIHAVRGGTIVGEHDVIFAGPNEVITISHSAQSREVFGYGALKAAKFLIGQKPG
LYTMEDLVKKG
>Mature_251_residues
MMIRLIIHGCNGKMGKVVAKLAKENPEFEVVAGVDKNTFPLDFPVYSDLKEVKEEADVVIDFSYHEAIPNLVKEAAKRKI
PVVIATTGLSEEELKTVEEASKEIPIFRSANMSLGINVLISLVKEAAKVLEGFDIEIVEKHHNMKKDAPSGTALMIADAI
NQVLPEKREYVYGRYTKTEQRKPNEIGIHAVRGGTIVGEHDVIFAGPNEVITISHSAQSREVFGYGALKAAKFLIGQKPG
LYTMEDLVKKG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=37.6425855513308, Blast_Score=147, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_THETN (Q8RBI6)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622484.1
- ProteinModelPortal:   Q8RBI6
- SMR:   Q8RBI6
- GeneID:   996961
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0831
- NMPDR:   fig|273068.3.peg.1081
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BioCyc:   TTEN273068:TTE0831-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27658; Mature: 27658

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIRLIIHGCNGKMGKVVAKLAKENPEFEVVAGVDKNTFPLDFPVYSDLKEVKEEADVVI
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEE
DFSYHEAIPNLVKEAAKRKIPVVIATTGLSEEELKTVEEASKEIPIFRSANMSLGINVLI
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
SLVKEAAKVLEGFDIEIVEKHHNMKKDAPSGTALMIADAINQVLPEKREYVYGRYTKTEQ
HHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCEEHHHHHHHHHCCCHHHHEECCCCCCCC
RKPNEIGIHAVRGGTIVGEHDVIFAGPNEVITISHSAQSREVFGYGALKAAKFLIGQKPG
CCCCCCCEEEEECCEEECCCCEEEECCCCEEEEECCCCCCEEECHHHHHHHHHHHCCCCC
LYTMEDLVKKG
CCCHHHHHHCC
>Mature Secondary Structure
MMIRLIIHGCNGKMGKVVAKLAKENPEFEVVAGVDKNTFPLDFPVYSDLKEVKEEADVVI
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEE
DFSYHEAIPNLVKEAAKRKIPVVIATTGLSEEELKTVEEASKEIPIFRSANMSLGINVLI
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
SLVKEAAKVLEGFDIEIVEKHHNMKKDAPSGTALMIADAINQVLPEKREYVYGRYTKTEQ
HHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCCEEHHHHHHHHHCCCHHHHEECCCCCCCC
RKPNEIGIHAVRGGTIVGEHDVIFAGPNEVITISHSAQSREVFGYGALKAAKFLIGQKPG
CCCCCCCEEEEECCEEECCCCEEEECCCCEEEEECCCCCCEEECHHHHHHHHHHHCCCCC
LYTMEDLVKKG
CCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336