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The map label for this gene is NagC2 [H]

Identifier: 20807245

GI number: 20807245

Start: 761051

End: 762061

Strand: Direct

Name: NagC2 [H]

Synonym: TTE0761

Alternate gene names: 20807245

Gene position: 761051-762061 (Clockwise)

Preceding gene: 20807244

Following gene: 20807246

Centisome position: 28.3

GC content: 34.52

Gene sequence:

>1011_bases
ATGAAAAATCATAATTTAGAAAAAAATGACCAAAAGTCAAAATATATAGTAGGAATTGATATAGGGGGTACAAAAACAGC
AGTTATTTTGGGAGATACCGAAGTTAACATTATAGATAGAATTGAATATTCTACCAAAGAATTTGACAAACAACCAATGA
AAATGATAAACAAAATGATTCAAACAATTAAAGATGTACTGCAAAACCATAACATAACACTTGAAGAAGTAAAAAGTATA
GGAATTAGTTCAGGAGGACCTTTGGACCTAGAAAAAGGCATTATATTATCGCCGCCTAACCTTCCAGGATGGGACGAGAT
TCCGATTGTTGATATATTATCCAATGAATTTAATGTTCCTGTATATTTGGAAAACGATGCAAATGCTGGCGCTGTTGCTG
AATGGAATTTTGGTTCAGGGGTGGGGTGTAAAAATTTAATTTTCTTAACATTTGGGACTGGCATGGGAGCGGGTCTTATT
CTTGATGGTAAATTGTACAGAGGCACCAATGGGATGGCTGGAGAGGTAGGACATATAAGATTAGCAAAAGATGGTCCTGT
CGGTTATGGCAAGAAAGGTTCCTTTGAAGGATTTTGCAGTGGAGGAGGAATTGCGCGTCTAGCTCAAATAGAAATTTCGA
AAAGATTGGCTAATGGTGAATCAGTAGAATTTTGTCCTTCGTTTGATATGCTTTCAAAAATTACTGCCGAAGATGTGGCT
GTTGCAGCACAAAAAGGGGATAAAGTTGCTTTAGAAATTATTAAGATAAGCGCTGAATATTTAGGTTTAGCTCTTTCAAT
TTTGATTGACATACTAAATCCAGAAAAGATTATTTTGGGAACTATTTTTACAAAAAATGAAAGTTTGTTTAGAAAAATAG
TAGAAGAAGTCATAAAAAGAGAGGCATTAGAAATTTCTGCAGGTGTATGTAAAATAGAACCTTCTAAACTTGGGAATAAA
ATAGGAGATTATGCTGCTTTGTCTGTAGCATTAAGAATAGGGATGGAGTGA

Upstream 100 bases:

>100_bases
AGGGAGTCATGTGGTTGTTTGTATGTAAGTAATAAAGTGGTATCTTGAATTATCATTACGTATCAACAAAATATAATGAG
ACCTACAGGAGGAGTTGCAA

Downstream 100 bases:

>100_bases
GGTAGATAATGAAAAAAAGCTTAAACTGGGGGATGCTTGATGAGTTAGTAAGTAGATTTCCGGAACTTAAATATCTGGAG
AGCTCTATTAAAACAGCTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKNHNLEKNDQKSKYIVGIDIGGTKTAVILGDTEVNIIDRIEYSTKEFDKQPMKMINKMIQTIKDVLQNHNITLEEVKSI
GISSGGPLDLEKGIILSPPNLPGWDEIPIVDILSNEFNVPVYLENDANAGAVAEWNFGSGVGCKNLIFLTFGTGMGAGLI
LDGKLYRGTNGMAGEVGHIRLAKDGPVGYGKKGSFEGFCSGGGIARLAQIEISKRLANGESVEFCPSFDMLSKITAEDVA
VAAQKGDKVALEIIKISAEYLGLALSILIDILNPEKIILGTIFTKNESLFRKIVEEVIKREALEISAGVCKIEPSKLGNK
IGDYAALSVALRIGME

Sequences:

>Translated_336_residues
MKNHNLEKNDQKSKYIVGIDIGGTKTAVILGDTEVNIIDRIEYSTKEFDKQPMKMINKMIQTIKDVLQNHNITLEEVKSI
GISSGGPLDLEKGIILSPPNLPGWDEIPIVDILSNEFNVPVYLENDANAGAVAEWNFGSGVGCKNLIFLTFGTGMGAGLI
LDGKLYRGTNGMAGEVGHIRLAKDGPVGYGKKGSFEGFCSGGGIARLAQIEISKRLANGESVEFCPSFDMLSKITAEDVA
VAAQKGDKVALEIIKISAEYLGLALSILIDILNPEKIILGTIFTKNESLFRKIVEEVIKREALEISAGVCKIEPSKLGNK
IGDYAALSVALRIGME
>Mature_336_residues
MKNHNLEKNDQKSKYIVGIDIGGTKTAVILGDTEVNIIDRIEYSTKEFDKQPMKMINKMIQTIKDVLQNHNITLEEVKSI
GISSGGPLDLEKGIILSPPNLPGWDEIPIVDILSNEFNVPVYLENDANAGAVAEWNFGSGVGCKNLIFLTFGTGMGAGLI
LDGKLYRGTNGMAGEVGHIRLAKDGPVGYGKKGSFEGFCSGGGIARLAQIEISKRLANGESVEFCPSFDMLSKITAEDVA
VAAQKGDKVALEIIKISAEYLGLALSILIDILNPEKIILGTIFTKNESLFRKIVEEVIKREALEISAGVCKIEPSKLGNK
IGDYAALSVALRIGME

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=290, Percent_Identity=27.9310344827586, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI190014632, Length=290, Percent_Identity=27.9310344827586, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI298566325, Length=290, Percent_Identity=27.9310344827586, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4885285, Length=290, Percent_Identity=27.9310344827586, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787878, Length=283, Percent_Identity=26.8551236749117, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786891, Length=328, Percent_Identity=24.390243902439, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081733, Length=295, Percent_Identity=26.7796610169492, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082230, Length=286, Percent_Identity=29.7202797202797, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787363, Length=318, Percent_Identity=24.2138364779874, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 36214; Mature: 36214

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHNLEKNDQKSKYIVGIDIGGTKTAVILGDTEVNIIDRIEYSTKEFDKQPMKMINKMI
CCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEECCCCCHHHHCHHHHHHHHHHH
QTIKDVLQNHNITLEEVKSIGISSGGPLDLEKGIILSPPNLPGWDEIPIVDILSNEFNVP
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCE
VYLENDANAGAVAEWNFGSGVGCKNLIFLTFGTGMGAGLILDGKLYRGTNGMAGEVGHIR
EEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEE
LAKDGPVGYGKKGSFEGFCSGGGIARLAQIEISKRLANGESVEFCPSFDMLSKITAEDVA
EECCCCCCCCCCCCCCCEECCCCEEEEHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHH
VAAQKGDKVALEIIKISAEYLGLALSILIDILNPEKIILGTIFTKNESLFRKIVEEVIKR
HHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHH
EALEISAGVCKIEPSKLGNKIGDYAALSVALRIGME
HHHHHHCCEEEECHHHHCCHHHHHHHEEHHHEECCC
>Mature Secondary Structure
MKNHNLEKNDQKSKYIVGIDIGGTKTAVILGDTEVNIIDRIEYSTKEFDKQPMKMINKMI
CCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEECCCCCHHHHCHHHHHHHHHHH
QTIKDVLQNHNITLEEVKSIGISSGGPLDLEKGIILSPPNLPGWDEIPIVDILSNEFNVP
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCE
VYLENDANAGAVAEWNFGSGVGCKNLIFLTFGTGMGAGLILDGKLYRGTNGMAGEVGHIR
EEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEE
LAKDGPVGYGKKGSFEGFCSGGGIARLAQIEISKRLANGESVEFCPSFDMLSKITAEDVA
EECCCCCCCCCCCCCCCEECCCCEEEEHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHH
VAAQKGDKVALEIIKISAEYLGLALSILIDILNPEKIILGTIFTKNESLFRKIVEEVIKR
HHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHH
EALEISAGVCKIEPSKLGNKIGDYAALSVALRIGME
HHHHHHCCEEEECHHHHCCHHHHHHHEEHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]