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The map label for this gene is GmhA [H]

Identifier: 20807246

GI number: 20807246

Start: 762070

End: 762720

Strand: Direct

Name: GmhA [H]

Synonym: TTE0762

Alternate gene names: 20807246

Gene position: 762070-762720 (Clockwise)

Preceding gene: 20807245

Following gene: 20807247

Centisome position: 28.34

GC content: 36.71

Gene sequence:

>651_bases
ATGAAAAAAAGCTTAAACTGGGGGATGCTTGATGAGTTAGTAAGTAGATTTCCGGAACTTAAATATCTGGAGAGCTCTAT
TAAAACAGCTGCAGAGGTTATTATAGAGTCATATGAAAAAGGTGGAAAGCTACTTGTATGTGGTAATGGTGGAAGTGCAG
CTGATTCGGAACATATAGTAGGGGAGCTTTTAAAAGGCTTCATGAAGAAAAGGCTGCTAAATGTGGAGACTATAAACAAG
CTAAAGAAGTTTGACTTTCCATGGGGAAATATCCTTGCTGAAAAGTTACAGGGTGGACTACCAGCTATTTCTCTTACCGC
TCACACAGCTTTTTTGACTGCTTTTATGAATGATGTAGATCCGGATTTAGTTTTTGCCCAGCAAGTTTTGGCATTAGGGA
AGAAGGAAGATGTTTTGATAGCACTAACTACTTCTGGCAATTCTAAAAACATTTTGTATGCCCTTTATACAGCGAAAGCT
TTAGAAATGACAAGTATATGCTTTACTGGGGAAAGTGGAGGAAAAGCAAAAGAGATATGTGATGTATTATTGAATGTTCC
TGCAAACGTTACTCATAAGGTTCAAGAGTATCATTTACCTATTTATCACGCCCTATGTGGAATTATAGAAGAATATTTCT
TTGAAGAATAA

Upstream 100 bases:

>100_bases
CAGGTGTATGTAAAATAGAACCTTCTAAACTTGGGAATAAAATAGGAGATTATGCTGCTTTGTCTGTAGCATTAAGAATA
GGGATGGAGTGAGGTAGATA

Downstream 100 bases:

>100_bases
TTGTAAATTTGAAAAGTCTATTTCAATGTAAGCGAGGAGATAAAAAATGGGAGAAGTATTGATTAGGATGGAAAATATAA
GCAAAGAATTTCCAGGCGTT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKKSLNWGMLDELVSRFPELKYLESSIKTAAEVIIESYEKGGKLLVCGNGGSAADSEHIVGELLKGFMKKRLLNVETINK
LKKFDFPWGNILAEKLQGGLPAISLTAHTAFLTAFMNDVDPDLVFAQQVLALGKKEDVLIALTTSGNSKNILYALYTAKA
LEMTSICFTGESGGKAKEICDVLLNVPANVTHKVQEYHLPIYHALCGIIEEYFFEE

Sequences:

>Translated_216_residues
MKKSLNWGMLDELVSRFPELKYLESSIKTAAEVIIESYEKGGKLLVCGNGGSAADSEHIVGELLKGFMKKRLLNVETINK
LKKFDFPWGNILAEKLQGGLPAISLTAHTAFLTAFMNDVDPDLVFAQQVLALGKKEDVLIALTTSGNSKNILYALYTAKA
LEMTSICFTGESGGKAKEICDVLLNVPANVTHKVQEYHLPIYHALCGIIEEYFFEE
>Mature_216_residues
MKKSLNWGMLDELVSRFPELKYLESSIKTAAEVIIESYEKGGKLLVCGNGGSAADSEHIVGELLKGFMKKRLLNVETINK
LKKFDFPWGNILAEKLQGGLPAISLTAHTAFLTAFMNDVDPDLVFAQQVLALGKKEDVLIALTTSGNSKNILYALYTAKA
LEMTSICFTGESGGKAKEICDVLLNVPANVTHKVQEYHLPIYHALCGIIEEYFFEE

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=217, Percent_Identity=29.4930875576037, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786416, Length=187, Percent_Identity=31.0160427807487, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 23806; Mature: 23806

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLNWGMLDELVSRFPELKYLESSIKTAAEVIIESYEKGGKLLVCGNGGSAADSEHIV
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHH
GELLKGFMKKRLLNVETINKLKKFDFPWGNILAEKLQGGLPAISLTAHTAFLTAFMNDVD
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCC
PDLVFAQQVLALGKKEDVLIALTTSGNSKNILYALYTAKALEMTSICFTGESGGKAKEIC
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEHHHHHHHHHEEEECCCCCCHHHHH
DVLLNVPANVTHKVQEYHLPIYHALCGIIEEYFFEE
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKSLNWGMLDELVSRFPELKYLESSIKTAAEVIIESYEKGGKLLVCGNGGSAADSEHIV
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHH
GELLKGFMKKRLLNVETINKLKKFDFPWGNILAEKLQGGLPAISLTAHTAFLTAFMNDVD
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCC
PDLVFAQQVLALGKKEDVLIALTTSGNSKNILYALYTAKALEMTSICFTGESGGKAKEIC
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEHHHHHHHHHEEEECCCCCCHHHHH
DVLLNVPANVTHKVQEYHLPIYHALCGIIEEYFFEE
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11373120; 12101286 [H]