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The map label for this gene is AtpH

Identifier: 20807127

GI number: 20807127

Start: 637328

End: 637861

Strand: Direct

Name: AtpH

Synonym: TTE0634

Alternate gene names: 20807127

Gene position: 637328-637861 (Clockwise)

Preceding gene: 20807126

Following gene: 20807128

Centisome position: 23.7

GC content: 32.96

Gene sequence:

>534_bases
ATGGAACAAATAATAGCAAAAAGGTATGCCTCTGCCCTCTTTGATGTGGCTAAAAAAGAAGACAGGGTAAAAGAATACTA
CGAAGAATTGAAAAAAGCTGTGGAGATATTGCAAACAGAAGCTGTATGGAAGATTTTTGTAAATAAAAGCATTGACAAGA
CAAAAAAGATGAAATTTGTTGAAGAAGTGCTAGAAGGTTTTTCAAAAGAAATTGTAAATTTTGTCAAAGTAGCAATATCA
AAGCACAGAGAAAATCTCATCAAAGAGATACTGAATGAGTTTGAAGCTTTGTATAAGGCTTACTTTAATATGATAGATGT
AAAAGTAATTTCTGCCTATCCTTTGAAAGAAGAAGTGTTAAATCTGGTCAGGGAAAAGCTAGAGAAAAAGTATAATAAAA
AGGTAAATTTGATTCCTGTAGTGGATAAGGAAATTTTAGGTGGCTTAAAGCTGGTCATTGGCAATACTGTAATTGACGGT
TCAATTAAAGCAAGACTTGAAGCTCTTCTCAAAAACATGCGTCAGGCTGTCTAA

Upstream 100 bases:

>100_bases
TGTCACATCTAATAATAGAAGCTGCTTCTAAGGTTTTAGAGAAAAAACTGCCTGTTGAGGATGAAGACCTTATTAAAGAG
GTCATTGAGGAGGCAGGGTC

Downstream 100 bases:

>100_bases
AATGAATTTAAGAAGGTGAAAAGCGTATGGGAATAAGACCAGAGGAAATTAGTTCTGTTTTGGCGGAAAAAATTAAAAAC
TTTGATTTTAGCGTAGAAAC

Product: F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein)

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MEQIIAKRYASALFDVAKKEDRVKEYYEELKKAVEILQTEAVWKIFVNKSIDKTKKMKFVEEVLEGFSKEIVNFVKVAIS
KHRENLIKEILNEFEALYKAYFNMIDVKVISAYPLKEEVLNLVREKLEKKYNKKVNLIPVVDKEILGGLKLVIGNTVIDG
SIKARLEALLKNMRQAV

Sequences:

>Translated_177_residues
MEQIIAKRYASALFDVAKKEDRVKEYYEELKKAVEILQTEAVWKIFVNKSIDKTKKMKFVEEVLEGFSKEIVNFVKVAIS
KHRENLIKEILNEFEALYKAYFNMIDVKVISAYPLKEEVLNLVREKLEKKYNKKVNLIPVVDKEILGGLKLVIGNTVIDG
SIKARLEALLKNMRQAV
>Mature_177_residues
MEQIIAKRYASALFDVAKKEDRVKEYYEELKKAVEILQTEAVWKIFVNKSIDKTKKMKFVEEVLEGFSKEIVNFVKVAIS
KHRENLIKEILNEFEALYKAYFNMIDVKVISAYPLKEEVLNLVREKLEKKYNKKVNLIPVVDKEILGGLKLVIGNTVIDG
SIKARLEALLKNMRQAV

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=177, Percent_Identity=25.4237288135593, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1790173, Length=165, Percent_Identity=29.0909090909091, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_THETN (Q8RC18)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622298.1
- ProteinModelPortal:   Q8RC18
- SMR:   Q8RC18
- GeneID:   996568
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0634
- NMPDR:   fig|273068.3.peg.309
- HOGENOM:   HBG668108
- OMA:   GNLIENY
- ProtClustDB:   CLSK2754718
- BioCyc:   TTEN273068:TTE0634-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 20552; Mature: 20552

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQIIAKRYASALFDVAKKEDRVKEYYEELKKAVEILQTEAVWKIFVNKSIDKTKKMKFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EEVLEGFSKEIVNFVKVAISKHRENLIKEILNEFEALYKAYFNMIDVKVISAYPLKEEVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NLVREKLEKKYNKKVNLIPVVDKEILGGLKLVIGNTVIDGSIKARLEALLKNMRQAV
HHHHHHHHHHHCCCCCEEECCCHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQIIAKRYASALFDVAKKEDRVKEYYEELKKAVEILQTEAVWKIFVNKSIDKTKKMKFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EEVLEGFSKEIVNFVKVAISKHRENLIKEILNEFEALYKAYFNMIDVKVISAYPLKEEVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NLVREKLEKKYNKKVNLIPVVDKEILGGLKLVIGNTVIDGSIKARLEALLKNMRQAV
HHHHHHHHHHHCCCCCEEECCCHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336