| Definition | Thermoanaerobacter tengcongensis MB4, complete genome. |
|---|---|
| Accession | NC_003869 |
| Length | 2,689,445 |
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The map label for this gene is CaiD [H]
Identifier: 20807045
GI number: 20807045
Start: 550572
End: 551354
Strand: Direct
Name: CaiD [H]
Synonym: TTE0544
Alternate gene names: 20807045
Gene position: 550572-551354 (Clockwise)
Preceding gene: 20807044
Following gene: 20807046
Centisome position: 20.47
GC content: 39.08
Gene sequence:
>783_bases GTGGAATATAAAAACATAGAAGTGAAAATTGAAAAGGGGATTGCCACAATCACAATTAACAGGCCAAAGGCTTTAAATGC ATTAAACACAGAGACTCTTGAAGAATTAGAAAATGTTTTAGAAGTTTTGCAAAATGACGATGGGGTAAAAGTTATAGTTA TAACTGGTGCAGGAGAAAAGGCATTTGTGGCAGGAGCAGATATTTCTGAAATGAAGGACATGAGCGTATTTGAGGCGAAA AAGTTTGCTGAGTTAGGTCAGAAGGTATTTAGAAAGATTGAACTTGTGAAGAAGCCAGTCATTGCTGCTGTGAATGGATA CGCTCTTGGAGGAGGATGTGAACTTGCTTTGGCTTGCGATATAAGGATTGCAAGTCGTAATGCAAAATTTGGTCAGCCAG AAGTAGGACTTGGAATTATACCGGGATTTGGTGGTACGCAGAGGCTACCTCGAATTGTAGGTGTTTCAAAAGCGAAAGAA CTCATATACACTGGAGATATGATAGATGCAGAGGAGGCTTTGAGAATAGGCCTTATTTCAAAAGTAGTAGAACAAGATAA ACTTTTAGAGGAAGCTTATGGTATTGCAAAAAAGATAATGTCAAAAGGGCTTGTGGCAGTATCACTGGCTAAAGAAGCTA TAAACAAAAGCCTCGAAGTTGATATCGATTCAGGCATGGAATATGAGGCCAATGCTTTTGCCATGTGTTTTGGTACACAG GATCAAAAAGAGGGCATGGCAGCTTTTTTAGAGAAGAGAGCTCCTAAATTTGAAGGAAGATGA
Upstream 100 bases:
>100_bases ACAGTGAAAGTAGATGGATGAAATGTCCATCTACTTTTTATTTTGGCATGATTTTTGCATAAAATATTAAAAGCGAAAAC TCAAAAGGAGGGTGACTTTG
Downstream 100 bases:
>100_bases GGGGAATGCCCCTCACTGTACCCTAGAATGTTAAAAAAATATCAAAAAGGAGGAGTGTATATGGATTTTTCTTTTACCAG AGAACAAGAGATGGTGAGAA
Product: 3-hydroxybutyryl-CoA dehydratase
Products: NA
Alternate protein names: Crotonase [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEKAFVAGADISEMKDMSVFEAK KFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACDIRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKE LIYTGDMIDAEEALRIGLISKVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ DQKEGMAAFLEKRAPKFEGR
Sequences:
>Translated_260_residues MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEKAFVAGADISEMKDMSVFEAK KFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACDIRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKE LIYTGDMIDAEEALRIGLISKVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ DQKEGMAAFLEKRAPKFEGR >Mature_260_residues MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEKAFVAGADISEMKDMSVFEAK KFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACDIRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKE LIYTGDMIDAEEALRIGLISKVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ DQKEGMAAFLEKRAPKFEGR
Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=245, Percent_Identity=47.7551020408163, Blast_Score=219, Evalue=2e-57, Organism=Homo sapiens, GI4502327, Length=252, Percent_Identity=42.4603174603175, Blast_Score=168, Evalue=4e-42, Organism=Homo sapiens, GI150378541, Length=254, Percent_Identity=35.8267716535433, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=35.1778656126482, Blast_Score=132, Evalue=2e-31, Organism=Homo sapiens, GI20127408, Length=239, Percent_Identity=33.8912133891213, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI68989263, Length=214, Percent_Identity=39.2523364485981, Blast_Score=129, Evalue=3e-30, Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=32.3308270676692, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI221136756, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI221136753, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI221307494, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI37594469, Length=250, Percent_Identity=31.2, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI37594471, Length=250, Percent_Identity=31.2, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI157694516, Length=247, Percent_Identity=28.3400809716599, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI213417737, Length=247, Percent_Identity=28.3400809716599, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI261878539, Length=114, Percent_Identity=44.7368421052632, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI62530384, Length=242, Percent_Identity=25.6198347107438, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI260274832, Length=218, Percent_Identity=30.7339449541284, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI45643119, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI260275230, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4757968, Length=262, Percent_Identity=24.4274809160305, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI49355787, Length=262, Percent_Identity=24.4274809160305, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI25453481, Length=260, Percent_Identity=24.6153846153846, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI51538573, Length=260, Percent_Identity=24.6153846153846, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI157694520, Length=222, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI116235487, Length=256, Percent_Identity=25, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI4757966, Length=249, Percent_Identity=24.8995983935743, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI51538581, Length=249, Percent_Identity=24.8995983935743, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI295842266, Length=240, Percent_Identity=22.9166666666667, Blast_Score=74, Evalue=1e-13, Organism=Escherichia coli, GI1787659, Length=255, Percent_Identity=43.5294117647059, Blast_Score=210, Evalue=6e-56, Organism=Escherichia coli, GI221142681, Length=251, Percent_Identity=38.2470119521912, Blast_Score=160, Evalue=6e-41, Organism=Escherichia coli, GI1790281, Length=200, Percent_Identity=38.5, Blast_Score=144, Evalue=5e-36, Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=36.3295880149813, Blast_Score=144, Evalue=6e-36, Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=35.7976653696498, Blast_Score=143, Evalue=1e-35, Organism=Escherichia coli, GI1788682, Length=189, Percent_Identity=41.7989417989418, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=30.1526717557252, Blast_Score=118, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=46.8992248062016, Blast_Score=222, Evalue=2e-58, Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=47.6, Blast_Score=211, Evalue=3e-55, Organism=Caenorhabditis elegans, GI17540714, Length=224, Percent_Identity=42.8571428571429, Blast_Score=186, Evalue=1e-47, Organism=Caenorhabditis elegans, GI17558304, Length=235, Percent_Identity=37.4468085106383, Blast_Score=135, Evalue=1e-32, Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=30.2325581395349, Blast_Score=127, Evalue=5e-30, Organism=Caenorhabditis elegans, GI25144276, Length=229, Percent_Identity=37.117903930131, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17508953, Length=229, Percent_Identity=37.117903930131, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17508951, Length=229, Percent_Identity=37.117903930131, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17536985, Length=245, Percent_Identity=31.0204081632653, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17560910, Length=251, Percent_Identity=33.4661354581673, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17540306, Length=241, Percent_Identity=30.7053941908714, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI25144160, Length=180, Percent_Identity=31.1111111111111, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI25144157, Length=180, Percent_Identity=31.1111111111111, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI25141363, Length=206, Percent_Identity=28.1553398058252, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17535521, Length=272, Percent_Identity=28.6764705882353, Blast_Score=78, Evalue=5e-15, Organism=Saccharomyces cerevisiae, GI6320241, Length=185, Percent_Identity=30.2702702702703, Blast_Score=94, Evalue=2e-20, Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=49.6124031007752, Blast_Score=233, Evalue=1e-61, Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=49.6124031007752, Blast_Score=233, Evalue=1e-61, Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=42.8571428571429, Blast_Score=196, Evalue=1e-50, Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=31.5384615384615, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI19920382, Length=265, Percent_Identity=30.9433962264151, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24583077, Length=185, Percent_Identity=38.3783783783784, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI24583079, Length=185, Percent_Identity=38.3783783783784, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI19921000, Length=185, Percent_Identity=38.3783783783784, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI21357171, Length=201, Percent_Identity=34.3283582089552, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI24654903, Length=190, Percent_Identity=30, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24650670, Length=197, Percent_Identity=32.48730964467, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI19921018, Length=181, Percent_Identity=33.1491712707182, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24583165, Length=247, Percent_Identity=25.9109311740891, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI28571730, Length=139, Percent_Identity=34.5323741007194, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI28571729, Length=139, Percent_Identity=34.5323741007194, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI45550169, Length=253, Percent_Identity=24.1106719367589, Blast_Score=75, Evalue=4e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.55 [H]
Molecular weight: Translated: 28131; Mature: 28131
Theoretical pI: Translated: 5.00; Mature: 5.00
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEK CCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE AFVAGADISEMKDMSVFEAKKFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACD EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCCEEEEEEE IRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKELIYTGDMIDAEEALRIGLIS EEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH KVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCC DQKEGMAAFLEKRAPKFEGR CHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure MEYKNIEVKIEKGIATITINRPKALNALNTETLEELENVLEVLQNDDGVKVIVITGAGEK CCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCE AFVAGADISEMKDMSVFEAKKFAELGQKVFRKIELVKKPVIAAVNGYALGGGCELALACD EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCCEEEEEEE IRIASRNAKFGQPEVGLGIIPGFGGTQRLPRIVGVSKAKELIYTGDMIDAEEALRIGLIS EEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH KVVEQDKLLEEAYGIAKKIMSKGLVAVSLAKEAINKSLEVDIDSGMEYEANAFAMCFGTQ HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCC DQKEGMAAFLEKRAPKFEGR CHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8655474; 11466286 [H]