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The map label for this gene is AraH2 [H]

Identifier: 20806813

GI number: 20806813

Start: 307338

End: 308528

Strand: Direct

Name: AraH2 [H]

Synonym: TTE0292

Alternate gene names: 20806813

Gene position: 307338-308528 (Clockwise)

Preceding gene: 20806812

Following gene: 20806818

Centisome position: 11.43

GC content: 39.29

Gene sequence:

>1191_bases
ATGAGATCTTTTTATGGGCATTTAAAAGAGTTTTTAAGGGAAAATGTCAGAGACTATGCAATGTTTATTGCTTTATTGGT
TATAATGATAGTTTTTGCAATTCTCTCTGGCGGCGATTTTCTCCTGCCCGTTAATATAAGCAACTTGGTGGATCAGACAG
GTTATATTGCGGTTTTGTCAATTGGGGAGACCTTGATAATAGTCATACGTCATATAGACCTTTCTGTAGGGTTTTTGTCA
GGATTTTTAGGGGCAATTGCCGCCATTCTGATGCAGTTTCACCATTTTTCAGCTTTTACTGCTATACTCATAGTCCTGAT
ATTGGGTACTTTAGCAGGGCTTTTAAACGGGTCATTGGTAGCTTATCTTAGAATTCCTGCTTTTGTGGCAACACTAGCAG
GATGGCTTGCTTATAGAGGAGCACTTCTTCTTGCTACAAAAGGGCCTGGTACCATAATAATAACAAATAAGACCTTTAAT
GCTATAGGAAATGACTTCATACCAGATTTGCCTTTTTTGAAGAATTTCATGCCAGGTTATCACAAACTCACCCTTTTGAT
AGGCATAATAGGAGTAGTGTTAATTGTATATTTTTCGCTTAAGAACAGAAATGAGCAAGCAAGAAGGGGATTTGATGTAC
TGCCATGGGATATGTTCCTTTTAAAAATGGTATTTATAAGTGGGCTGTTGTTGTATTTGACCTTTACTTTGGCTCGCTAC
AGAGGTATTTCCTGGACATTTGTAATAGTTTTGATTGTAACAGCAGTATACAGTTTTATAACAAATAGAACGGTATTAGG
AAGGCATATATACGCTGTAGGGGGAAACCCTGAAGCAGCTGCGTTAAGTGGTATAGACGTTAATAAGATAACTCTCATTG
TATTTGCCTCCATGGGATTTCTCTCAGGGCTTTCTGGAGTACTTTTTGCATCCAGACTTCAATCTGCTACGACTACTGCC
GGTACCTTGTTTGAGCTTTACGCTATTGCTGGTGCCTTCATAGGAGGAGTGTCAGCAAGCGGCGGTGTGGGTAAAGTTGT
AAATTCTCTCATTGGAGCTTTTGTGATGAGTACCTTGACAAACGGCATGAACTTGCTGGGAGTCGATATTTCACTTCAGT
ATATAATTTTAGGGCTGGTTTTAGCTACAGCTGTGATATTCGATGTGGCAACTAGAAGCAGAGGAAGATAA

Upstream 100 bases:

>100_bases
CGTCATGAGCAAAGGAAGGATAACAGGAGAGCTCAAAGGAGACGAAGCAAATCAGGAAAAAGTAATGGCCTACGCAGTCA
TCTGAAGGAGGTTAACCGCG

Downstream 100 bases:

>100_bases
AAAGCGGGGGCAAAAACCCCGCTTTTTTATATCCCCCAGCTTCTCTCGATGGTCCTCCTTTATTTTGTCCACCTGATGAC
AGGATTTCTAGCAGCCAGCA

Product: ribose/xylose/arabinose/galactoside ABC-type transporter permease

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRSFYGHLKEFLRENVRDYAMFIALLVIMIVFAILSGGDFLLPVNISNLVDQTGYIAVLSIGETLIIVIRHIDLSVGFLS
GFLGAIAAILMQFHHFSAFTAILIVLILGTLAGLLNGSLVAYLRIPAFVATLAGWLAYRGALLLATKGPGTIIITNKTFN
AIGNDFIPDLPFLKNFMPGYHKLTLLIGIIGVVLIVYFSLKNRNEQARRGFDVLPWDMFLLKMVFISGLLLYLTFTLARY
RGISWTFVIVLIVTAVYSFITNRTVLGRHIYAVGGNPEAAALSGIDVNKITLIVFASMGFLSGLSGVLFASRLQSATTTA
GTLFELYAIAGAFIGGVSASGGVGKVVNSLIGAFVMSTLTNGMNLLGVDISLQYIILGLVLATAVIFDVATRSRGR

Sequences:

>Translated_396_residues
MRSFYGHLKEFLRENVRDYAMFIALLVIMIVFAILSGGDFLLPVNISNLVDQTGYIAVLSIGETLIIVIRHIDLSVGFLS
GFLGAIAAILMQFHHFSAFTAILIVLILGTLAGLLNGSLVAYLRIPAFVATLAGWLAYRGALLLATKGPGTIIITNKTFN
AIGNDFIPDLPFLKNFMPGYHKLTLLIGIIGVVLIVYFSLKNRNEQARRGFDVLPWDMFLLKMVFISGLLLYLTFTLARY
RGISWTFVIVLIVTAVYSFITNRTVLGRHIYAVGGNPEAAALSGIDVNKITLIVFASMGFLSGLSGVLFASRLQSATTTA
GTLFELYAIAGAFIGGVSASGGVGKVVNSLIGAFVMSTLTNGMNLLGVDISLQYIILGLVLATAVIFDVATRSRGR
>Mature_396_residues
MRSFYGHLKEFLRENVRDYAMFIALLVIMIVFAILSGGDFLLPVNISNLVDQTGYIAVLSIGETLIIVIRHIDLSVGFLS
GFLGAIAAILMQFHHFSAFTAILIVLILGTLAGLLNGSLVAYLRIPAFVATLAGWLAYRGALLLATKGPGTIIITNKTFN
AIGNDFIPDLPFLKNFMPGYHKLTLLIGIIGVVLIVYFSLKNRNEQARRGFDVLPWDMFLLKMVFISGLLLYLTFTLARY
RGISWTFVIVLIVTAVYSFITNRTVLGRHIYAVGGNPEAAALSGIDVNKITLIVFASMGFLSGLSGVLFASRLQSATTTA
GTLFELYAIAGAFIGGVSASGGVGKVVNSLIGAFVMSTLTNGMNLLGVDISLQYIILGLVLATAVIFDVATRSRGR

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=380, Percent_Identity=35, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1790191, Length=154, Percent_Identity=44.8051948051948, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790524, Length=157, Percent_Identity=41.4012738853503, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693152, Length=152, Percent_Identity=36.8421052631579, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788896, Length=156, Percent_Identity=32.6923076923077, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788471, Length=406, Percent_Identity=29.8029556650246, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693214, Length=327, Percent_Identity=30.2752293577982, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082395, Length=120, Percent_Identity=34.1666666666667, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 42694; Mature: 42694

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFYGHLKEFLRENVRDYAMFIALLVIMIVFAILSGGDFLLPVNISNLVDQTGYIAVLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCEEEEE
IGETLIIVIRHIDLSVGFLSGFLGAIAAILMQFHHFSAFTAILIVLILGTLAGLLNGSLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AYLRIPAFVATLAGWLAYRGALLLATKGPGTIIITNKTFNAIGNDFIPDLPFLKNFMPGY
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCHHHCCCCCCCCCHHHHHHCCCH
HKLTLLIGIIGVVLIVYFSLKNRNEQARRGFDVLPWDMFLLKMVFISGLLLYLTFTLARY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGISWTFVIVLIVTAVYSFITNRTVLGRHIYAVGGNPEAAALSGIDVNKITLIVFASMGF
CCCHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCCHHEECCCCHHHHHHHHHHHHHH
LSGLSGVLFASRLQSATTTAGTLFELYAIAGAFIGGVSASGGVGKVVNSLIGAFVMSTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
NGMNLLGVDISLQYIILGLVLATAVIFDVATRSRGR
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSFYGHLKEFLRENVRDYAMFIALLVIMIVFAILSGGDFLLPVNISNLVDQTGYIAVLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCEEEEE
IGETLIIVIRHIDLSVGFLSGFLGAIAAILMQFHHFSAFTAILIVLILGTLAGLLNGSLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AYLRIPAFVATLAGWLAYRGALLLATKGPGTIIITNKTFNAIGNDFIPDLPFLKNFMPGY
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCHHHCCCCCCCCCHHHHHHCCCH
HKLTLLIGIIGVVLIVYFSLKNRNEQARRGFDVLPWDMFLLKMVFISGLLLYLTFTLARY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGISWTFVIVLIVTAVYSFITNRTVLGRHIYAVGGNPEAAALSGIDVNKITLIVFASMGF
CCCHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCCHHEECCCCHHHHHHHHHHHHHH
LSGLSGVLFASRLQSATTTAGTLFELYAIAGAFIGGVSASGGVGKVVNSLIGAFVMSTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
NGMNLLGVDISLQYIILGLVLATAVIFDVATRSRGR
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]