Click here to switch to the map view.

The map label for this gene is AhpC [C]

Identifier: 20806791

GI number: 20806791

Start: 283923

End: 284585

Strand: Reverse

Name: AhpC [C]

Synonym: TTE0270

Alternate gene names: 20806791

Gene position: 284585-283923 (Counterclockwise)

Preceding gene: 20806792

Following gene: 20806789

Centisome position: 10.58

GC content: 41.33

Gene sequence:

>663_bases
ATGGAGGAAATTAGAATGAAGTTACTAGGAGAAAAATTCCCATCTATGGAGGTAATGACAACTCACGGAGTAAAGAGATT
GCCTGAAGACTATGCAGGAAAATGGTTTGTGCTCTTCAGCCATCCAGCGGACTTCACACCAGTTTGCACAACAGAGTTTG
TAGAATTTGCAAGAAAAGCTGAGGAATTCAAGCAATTAAACACTGAACTCATTGGGCTTTCAGTCGACCAGGTATTCTCT
CACATCAAATGGGTAGAGTGGATAAAGGACAACACAGGAGTACAAATCCCCTTCCCAGTAATAGCCGATGAACTAGGAAG
AGTATCCAACCAATTAGGAATGATTCATCCAGGAAAAGGAACAAACACAGTGAGAGCAGTATTCATTGTAGATGACAAAG
GAGTAATAAGGCTTATCATGTACTATCCACAGGAAGTAGGAAGAAACGTGGATGAAATACTAAGAGCGCTGAAAGCACTG
CAAACAGCAGACCAGTACGGCGTCGCACTTCCTGAGAAGTGGCCAAACAACTACTTAATTAAAGACCACGTTATAGTTCC
TCCTTCCACTGATGAAGCTTCTGCCAATGAGAGAAAAGAAAAGATAAAGGCAAAAGAAATTGAGGCTTTTGACTGGTGGT
TCGTACACAAACCTTTGAAATAA

Upstream 100 bases:

>100_bases
GAATTAGAAGGGTTTACAATTAAGAGCATTGACATAAATGCCTATGGCATATGCAAAAAATGCAATGAAAAAATAAAAAA
TAATAAGGAGGAAGAGTAAA

Downstream 100 bases:

>100_bases
GGTCACCCATAAAATATCCCTTTTTTTCAACAAAGCGGGCTTGAAATCTTCAAGCCCGCTTTTATTGTTTTTTTAACATT
ATATCCAGAATTACATCATC

Product: putative peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MEEIRMKLLGEKFPSMEVMTTHGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKAEEFKQLNTELIGLSVDQVFS
HIKWVEWIKDNTGVQIPFPVIADELGRVSNQLGMIHPGKGTNTVRAVFIVDDKGVIRLIMYYPQEVGRNVDEILRALKAL
QTADQYGVALPEKWPNNYLIKDHVIVPPSTDEASANERKEKIKAKEIEAFDWWFVHKPLK

Sequences:

>Translated_220_residues
MEEIRMKLLGEKFPSMEVMTTHGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKAEEFKQLNTELIGLSVDQVFS
HIKWVEWIKDNTGVQIPFPVIADELGRVSNQLGMIHPGKGTNTVRAVFIVDDKGVIRLIMYYPQEVGRNVDEILRALKAL
QTADQYGVALPEKWPNNYLIKDHVIVPPSTDEASANERKEKIKAKEIEAFDWWFVHKPLK
>Mature_220_residues
MEEIRMKLLGEKFPSMEVMTTHGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKAEEFKQLNTELIGLSVDQVFS
HIKWVEWIKDNTGVQIPFPVIADELGRVSNQLGMIHPGKGTNTVRAVFIVDDKGVIRLIMYYPQEVGRNVDEILRALKAL
QTADQYGVALPEKWPNNYLIKDHVIVPPSTDEASANERKEKIKAKEIEAFDWWFVHKPLK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=199, Percent_Identity=38.1909547738693, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI4505591, Length=158, Percent_Identity=40.5063291139241, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI32455266, Length=158, Percent_Identity=40.5063291139241, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI32455264, Length=158, Percent_Identity=40.5063291139241, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI32189392, Length=158, Percent_Identity=39.873417721519, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI5453549, Length=146, Percent_Identity=39.7260273972603, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5802974, Length=155, Percent_Identity=38.0645161290323, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI32483377, Length=155, Percent_Identity=38.0645161290323, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI33188454, Length=58, Percent_Identity=50, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786822, Length=147, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=147, Percent_Identity=36.734693877551, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25153706, Length=195, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI32565831, Length=175, Percent_Identity=36.5714285714286, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193204376, Length=175, Percent_Identity=36.5714285714286, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319407, Length=192, Percent_Identity=44.2708333333333, Blast_Score=141, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=158, Percent_Identity=36.0759493670886, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6320661, Length=158, Percent_Identity=34.1772151898734, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17975518, Length=194, Percent_Identity=41.2371134020619, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652434, Length=194, Percent_Identity=41.2371134020619, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24652436, Length=194, Percent_Identity=40.7216494845361, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17738015, Length=179, Percent_Identity=36.3128491620112, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24581278, Length=172, Percent_Identity=38.953488372093, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17157991, Length=147, Percent_Identity=38.7755102040816, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641739, Length=147, Percent_Identity=38.7755102040816, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24656348, Length=164, Percent_Identity=35.3658536585366, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17864676, Length=164, Percent_Identity=35.3658536585366, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21357347, Length=146, Percent_Identity=34.9315068493151, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25298; Mature: 25298

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIRMKLLGEKFPSMEVMTTHGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKA
CCHHHHHHHHCCCCCCEEHHHHHHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHH
EEFKQLNTELIGLSVDQVFSHIKWVEWIKDNTGVQIPFPVIADELGRVSNQLGMIHPGKG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHCCCEECCCC
TNTVRAVFIVDDKGVIRLIMYYPQEVGRNVDEILRALKALQTADQYGVALPEKWPNNYLI
CCEEEEEEEECCCCCEEHHEECCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
KDHVIVPPSTDEASANERKEKIKAKEIEAFDWWFVHKPLK
ECCEEECCCCCCCCHHHHHHHHHHHHCCHHHEEEEECCCC
>Mature Secondary Structure
MEEIRMKLLGEKFPSMEVMTTHGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKA
CCHHHHHHHHCCCCCCEEHHHHHHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHH
EEFKQLNTELIGLSVDQVFSHIKWVEWIKDNTGVQIPFPVIADELGRVSNQLGMIHPGKG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHCCCEECCCC
TNTVRAVFIVDDKGVIRLIMYYPQEVGRNVDEILRALKALQTADQYGVALPEKWPNNYLI
CCEEEEEEEECCCCCEEHHEECCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
KDHVIVPPSTDEASANERKEKIKAKEIEAFDWWFVHKPLK
ECCEEECCCCCCCCHHHHHHHHHHHHCCHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]