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The map label for this gene is RbsK [H]

Identifier: 20806728

GI number: 20806728

Start: 208536

End: 209456

Strand: Direct

Name: RbsK [H]

Synonym: TTE0202

Alternate gene names: 20806728

Gene position: 208536-209456 (Clockwise)

Preceding gene: 20806727

Following gene: 20806729

Centisome position: 7.75

GC content: 33.33

Gene sequence:

>921_bases
ATGAGAAAAATAGTTGTTGTAGGAAGCATTAACATGGATATTGTAATAAGAGTACCGCGCATTCCAGTTGTTGGAGAGAC
AGTTATTGCTTACGATTTAAAAAATTATGGTGGTGGTAAAGGTGCAAACCAGGCTGTATCTATAGCTAGGTTAGGTGGAA
ATGTTTCTATGATTGGTCGAGTAGGAAATGATGAGTATGGCCAAAAATTATATAGGGATTTAAAAAGCAATGGGGTAGGT
GTAGAAGGAATAGAATTTGATTCAGAGACTCCCACAGGTACAGCATATATTAACGTGAGTGAAAAAGGAGAAAACAATAT
AGTAGTTTATCAGGGTGCAAACAAGAGGCTTAATATGACACAAATAAAAAGATATGAGCATTTTTTTGATGAAGCAGAAA
TATGTCTTCTTCAATTAGAAATACCAATTGAAACAGTGAAGTTTGTAGTAGATTTGTGCTATAGCAGAGGGATAAAAGTT
ATATTAAATCCTGCACCAGCATACGAATTGCCTGATACAGTTTTAGAGAAAGTTTATATTTTGACTCCAAATGAAACAGA
GTTAGCTTTTTTATCCAAAAGCAAAATAGAAACAATTGAAGATATAAGAAAGGCTTCGAAATATTTGCTAGACAAAGGAG
TTCAAAATGTTATAACAACTATTGGAGAAAAAGGAAGTTATTTTATTAATAAAAATACGGAAAAACTATTTGATGCAATT
AAAGTTACTGCTGTTGATACAACAGCAGCAGGTGATTCATTTACAGGAGCGTTAGCTTTTGCTTTAAGCAAAGGGGAAAA
AATAGAGGATGCAATAAGATTTGCTACATTTGTTGCTGCACTTACAGTTACTAAAGAAGGTGCCCAGACTTCTTTGCCTT
ATAAAGAAGAAGTAGAAAAATTTATTAAGGAGAGGAGTTGA

Upstream 100 bases:

>100_bases
AAAGCTTATAGAAGGTAAAAAACTGAAGAAAAAAATTATTAATTTTAGACCGCAGTTGGTAATCCGGCAAAGTACTAAAT
TAGTCAAAGGTGGGTAAAAA

Downstream 100 bases:

>100_bases
AACAATGAAGAAAACGGAATTATTAAATAGTGAAATTTCAGAAGTAGTTGCAAGATTAGGGCACAAAGATTTATTAGTAA
TTGCTGATAGCGGGTTACCT

Product: ribokinase family sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRKIVVVGSINMDIVIRVPRIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGNVSMIGRVGNDEYGQKLYRDLKSNGVG
VEGIEFDSETPTGTAYINVSEKGENNIVVYQGANKRLNMTQIKRYEHFFDEAEICLLQLEIPIETVKFVVDLCYSRGIKV
ILNPAPAYELPDTVLEKVYILTPNETELAFLSKSKIETIEDIRKASKYLLDKGVQNVITTIGEKGSYFINKNTEKLFDAI
KVTAVDTTAAGDSFTGALAFALSKGEKIEDAIRFATFVAALTVTKEGAQTSLPYKEEVEKFIKERS

Sequences:

>Translated_306_residues
MRKIVVVGSINMDIVIRVPRIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGNVSMIGRVGNDEYGQKLYRDLKSNGVG
VEGIEFDSETPTGTAYINVSEKGENNIVVYQGANKRLNMTQIKRYEHFFDEAEICLLQLEIPIETVKFVVDLCYSRGIKV
ILNPAPAYELPDTVLEKVYILTPNETELAFLSKSKIETIEDIRKASKYLLDKGVQNVITTIGEKGSYFINKNTEKLFDAI
KVTAVDTTAAGDSFTGALAFALSKGEKIEDAIRFATFVAALTVTKEGAQTSLPYKEEVEKFIKERS
>Mature_306_residues
MRKIVVVGSINMDIVIRVPRIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGNVSMIGRVGNDEYGQKLYRDLKSNGVG
VEGIEFDSETPTGTAYINVSEKGENNIVVYQGANKRLNMTQIKRYEHFFDEAEICLLQLEIPIETVKFVVDLCYSRGIKV
ILNPAPAYELPDTVLEKVYILTPNETELAFLSKSKIETIEDIRKASKYLLDKGVQNVITTIGEKGSYFINKNTEKLFDAI
KVTAVDTTAAGDSFTGALAFALSKGEKIEDAIRFATFVAALTVTKEGAQTSLPYKEEVEKFIKERS

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=303, Percent_Identity=35.6435643564356, Blast_Score=167, Evalue=9e-42,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=37.953795379538, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI87082343, Length=305, Percent_Identity=26.8852459016393, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788491, Length=294, Percent_Identity=23.1292517006803, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788484, Length=287, Percent_Identity=25.7839721254355, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081971, Length=310, Percent_Identity=24.8387096774194, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788017, Length=272, Percent_Identity=23.8970588235294, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=39.7350993377483, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=32.5301204819277, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=34.1059602649007, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=30.6930693069307, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33698; Mature: 33698

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVVVGSINMDIVIRVPRIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGNVSMIGR
CCEEEEEEECCEEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCHHEEEEEECCCEEEEEE
VGNDEYGQKLYRDLKSNGVGVEGIEFDSETPTGTAYINVSEKGENNIVVYQGANKRLNMT
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCHH
QIKRYEHFFDEAEICLLQLEIPIETVKFVVDLCYSRGIKVILNPAPAYELPDTVLEKVYI
HHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCEEEE
LTPNETELAFLSKSKIETIEDIRKASKYLLDKGVQNVITTIGEKGSYFINKNTEKLFDAI
ECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
KVTAVDTTAAGDSFTGALAFALSKGEKIEDAIRFATFVAALTVTKEGAQTSLPYKEEVEK
EEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHH
FIKERS
HHHHCC
>Mature Secondary Structure
MRKIVVVGSINMDIVIRVPRIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGNVSMIGR
CCEEEEEEECCEEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCHHEEEEEECCCEEEEEE
VGNDEYGQKLYRDLKSNGVGVEGIEFDSETPTGTAYINVSEKGENNIVVYQGANKRLNMT
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCHH
QIKRYEHFFDEAEICLLQLEIPIETVKFVVDLCYSRGIKVILNPAPAYELPDTVLEKVYI
HHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCEEEE
LTPNETELAFLSKSKIETIEDIRKASKYLLDKGVQNVITTIGEKGSYFINKNTEKLFDAI
ECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
KVTAVDTTAAGDSFTGALAFALSKGEKIEDAIRFATFVAALTVTKEGAQTSLPYKEEVEK
EEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHH
FIKERS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]