Click here to switch to the map view.

The map label for this gene is Rpe [H]

Identifier: 20806711

GI number: 20806711

Start: 188930

End: 189574

Strand: Direct

Name: Rpe [H]

Synonym: TTE0185

Alternate gene names: 20806711

Gene position: 188930-189574 (Clockwise)

Preceding gene: 20806709

Following gene: 20806712

Centisome position: 7.02

GC content: 33.8

Gene sequence:

>645_bases
ATGAAGATTTCAGCTTCTATATTGGCCGCTGATACAGCTTTTTTAGGTAAGGAAGTTTTAGAACTGGAAAAATTAGGTAT
AGATTTTATTCATGTGGATGTTATAGACGGTCACTATGCAAATAATTTCGGATTTAGCCCTAAAACTGTTAAAGATTTAA
GACGAATAACTGACTTACCAATAGAAGTTCATTTGGAAATATTAAATCCAGAAAACTATGTCGAAATATTTTCAGAAGCT
GGGGCAGATATTATAATAGTCCAATTTGATACTTGTAGCCATCCTTTGCGAATTTTAAGAAAAATCAAGGCTTTAGGTAA
AAAAGCTGGTGTTGCTTTAAGCCCATGTGTTTCTTTTGAAAGCTTAAGATGGTGTTTAAATGATGTGGATTATTTGTTGT
TCATGAGTGTGGAACCCGGGTTTGGGGGACAAAATTTTGAAACTTTTACCATAGACAAGATAAAATTAGCGAAAGTTCAA
CTGAAAGAGATGGGGTTTTCTATTCCCATAGGGGTGGATGGAGGAGTAAATTTAGGCAATATAAACTTACTGAGAGAAGT
GGGGGTAGATATTGTAGTGGTAGGAAGTGCACTATTTTTAAATGAAAACAAAGAAAGATTTATTTTCCAAGTAAAAGGAG
GTTAA

Upstream 100 bases:

>100_bases
CTTTTGCTTGACTTTTTAAAAAAGATAAGTTAAACTAAATAATAAGGAGCACGATTGATATCAATAGGAACATTTGTTAC
TAAATTTATGGAGGGCAAAA

Downstream 100 bases:

>100_bases
GAAATGATTGTATCTCACAAAGACAAAAAAACACCTGCTTATATACCCTCTAATGCCCTTCATCAGTTTGTAAACATGGG
AGAAGAGGTACTTGAGCTTA

Product: Pentose-5-phosphate-3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKISASILAADTAFLGKEVLELEKLGIDFIHVDVIDGHYANNFGFSPKTVKDLRRITDLPIEVHLEILNPENYVEIFSEA
GADIIIVQFDTCSHPLRILRKIKALGKKAGVALSPCVSFESLRWCLNDVDYLLFMSVEPGFGGQNFETFTIDKIKLAKVQ
LKEMGFSIPIGVDGGVNLGNINLLREVGVDIVVVGSALFLNENKERFIFQVKGG

Sequences:

>Translated_214_residues
MKISASILAADTAFLGKEVLELEKLGIDFIHVDVIDGHYANNFGFSPKTVKDLRRITDLPIEVHLEILNPENYVEIFSEA
GADIIIVQFDTCSHPLRILRKIKALGKKAGVALSPCVSFESLRWCLNDVDYLLFMSVEPGFGGQNFETFTIDKIKLAKVQ
LKEMGFSIPIGVDGGVNLGNINLLREVGVDIVVVGSALFLNENKERFIFQVKGG
>Mature_214_residues
MKISASILAADTAFLGKEVLELEKLGIDFIHVDVIDGHYANNFGFSPKTVKDLRRITDLPIEVHLEILNPENYVEIFSEA
GADIIIVQFDTCSHPLRILRKIKALGKKAGVALSPCVSFESLRWCLNDVDYLLFMSVEPGFGGQNFETFTIDKIKLAKVQ
LKEMGFSIPIGVDGGVNLGNINLLREVGVDIVVVGSALFLNENKERFIFQVKGG

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=209, Percent_Identity=34.4497607655502, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI219879828, Length=209, Percent_Identity=32.5358851674641, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI24307923, Length=164, Percent_Identity=28.6585365853659, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789788, Length=211, Percent_Identity=37.4407582938389, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790523, Length=203, Percent_Identity=30.0492610837438, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1790754, Length=210, Percent_Identity=25.7142857142857, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=201, Percent_Identity=32.3383084577114, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322341, Length=219, Percent_Identity=31.0502283105023, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=33.0188679245283, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23626; Mature: 23626

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISASILAADTAFLGKEVLELEKLGIDFIHVDVIDGHYANNFGFSPKTVKDLRRITDLP
CCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
IEVHLEILNPENYVEIFSEAGADIIIVQFDTCSHPLRILRKIKALGKKAGVALSPCVSFE
EEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCCCHH
SLRWCLNDVDYLLFMSVEPGFGGQNFETFTIDKIKLAKVQLKEMGFSIPIGVDGGVNLGN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEEECEEEEHEEEHHHCCCEEEECCCCCCCCCC
INLLREVGVDIVVVGSALFLNENKERFIFQVKGG
HHHHHHCCCCEEEEEEEEEECCCCCEEEEEECCC
>Mature Secondary Structure
MKISASILAADTAFLGKEVLELEKLGIDFIHVDVIDGHYANNFGFSPKTVKDLRRITDLP
CCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
IEVHLEILNPENYVEIFSEAGADIIIVQFDTCSHPLRILRKIKALGKKAGVALSPCVSFE
EEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCCCHH
SLRWCLNDVDYLLFMSVEPGFGGQNFETFTIDKIKLAKVQLKEMGFSIPIGVDGGVNLGN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEEECEEEEHEEEHHHCCCEEEECCCCCCCCCC
INLLREVGVDIVVVGSALFLNENKERFIFQVKGG
HHHHHHCCCCEEEEEEEEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]