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The map label for this gene is gatC [H]

Identifier: 20806709

GI number: 20806709

Start: 186528

End: 187775

Strand: Direct

Name: gatC [H]

Synonym: TTE0183

Alternate gene names: 20806709

Gene position: 186528-187775 (Clockwise)

Preceding gene: 20806708

Following gene: 20806711

Centisome position: 6.94

GC content: 38.54

Gene sequence:

>1248_bases
ATGAGTATTATCAAATATATTTTGGATTTGGGAGCAACAGTAATGCTTCCAATAATAATTTTCTTACTGGCCCTTATATT
AGGAGAAAAACCAGGTAGAGCTTTCAGATCAGCACTTACTATAGGAATAGGTTTTGTGGGGATAAATCTAGTAATTGGAT
TACTCGTTAATAACCTCGGTCCTGCGGCTCAAGCAATGGTAGAACATATGGGAGTTCATCTTAACGTAATAGACGTCGGT
TGGCCTGCTTCTGCAGCAATTGCTTTTGCCTCAAAAGTAGGAGCTTTTGTTATTCCTATAGGTCTTTTAGTAAATATAAT
AATGCTTGCTACCAGACTTACAAAAACTGTAAACGTAGACTTATGGAATTATTGGCATTTCGCATTCACTGGAGCTTTAG
TGACAGCTGCTACAGGAAGCCTAACATGGGGATTGGTTGCAGCAGCAATAAATGCCGCGATTGTTTTATTGCTAGCCGAC
TGGACAGCAAAAATGGTGCAGGATTTCTATGGCTTACCAGGTATATCACTTCCACACGGATTTTCTGCGGCTTATGTTCC
AATAGCTATTCCTCTTAATAAACTCATAGACAAAATCCCAGTTATAAACAAAATTGAAGCGGATACAGATACAATAAACA
AAAGATTCGGCATTTTTGGTGAACCTATTGTGATAGGATTAATTTTGGGTGTTGTTCTAGGTATATTGGCAAAATACGAT
GTGAAAGGAATTTTAAACTTGGGTATTTCAATGGCTGCTGTAATGCTTTTACTGCCCAGGATGGTACGAATTTTAATGGA
AGGATTAATCCCTATCTCTGAAGCAGCAAAAGCTTTTATGCAAAAGAGATTTCAAGGCAGAGAATTTTACATTGGACTTG
ATTCTGCAATAGCTGTTGGACACCCTGCTGCAATAGCCACAGCATTGGTATTAGTTCCCATAACTATACTTCTTGCAATA
ATATTGCCTGGTAACCATGTGTTGCCTTTTGGTGATTTGGCTACAATTCCTTTTATGGTAGTTATGGTTGTACCGGTAAC
TAAGGGTAATGTCTTTAGGTCTATATTGATTGGTACAATAGTTATAGGAGTGGGATTGTGGATTGCAACAAATGTGGCTC
CTTTGTTTACTCAGGTTGCTGCAGAAGCTGCCTTCAAGTTCCCAACTGGAGCTACAGAAATATCCAGCATATGCGATGGT
GCTAATCCTTTGACATGGGTGATTTTGCAGATAATGAGGCTATTTTAA

Upstream 100 bases:

>100_bases
GGGAAAAAAAGTATAAATGCACTTCCTCTTATAACAGGTATAGGAGAAGAACAAGTATTGAAAGAAATTATTGAAGAAAT
AAAGAAGTGAGGTGTAATCT

Downstream 100 bases:

>100_bases
AAAATGGGAGGGCTTCCTCCCATTTAATTTTCAATTAAATAGTGAGCTACTTCTATATCTGTGACAAGTATATCTATCCA
TTTTCCTACTAAAGCAGCTT

Product: hypothetical protein

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSIIKYILDLGATVMLPIIIFLLALILGEKPGRAFRSALTIGIGFVGINLVIGLLVNNLGPAAQAMVEHMGVHLNVIDVG
WPASAAIAFASKVGAFVIPIGLLVNIIMLATRLTKTVNVDLWNYWHFAFTGALVTAATGSLTWGLVAAAINAAIVLLLAD
WTAKMVQDFYGLPGISLPHGFSAAYVPIAIPLNKLIDKIPVINKIEADTDTINKRFGIFGEPIVIGLILGVVLGILAKYD
VKGILNLGISMAAVMLLLPRMVRILMEGLIPISEAAKAFMQKRFQGREFYIGLDSAIAVGHPAAIATALVLVPITILLAI
ILPGNHVLPFGDLATIPFMVVMVVPVTKGNVFRSILIGTIVIGVGLWIATNVAPLFTQVAAEAAFKFPTGATEISSICDG
ANPLTWVILQIMRLF

Sequences:

>Translated_415_residues
MSIIKYILDLGATVMLPIIIFLLALILGEKPGRAFRSALTIGIGFVGINLVIGLLVNNLGPAAQAMVEHMGVHLNVIDVG
WPASAAIAFASKVGAFVIPIGLLVNIIMLATRLTKTVNVDLWNYWHFAFTGALVTAATGSLTWGLVAAAINAAIVLLLAD
WTAKMVQDFYGLPGISLPHGFSAAYVPIAIPLNKLIDKIPVINKIEADTDTINKRFGIFGEPIVIGLILGVVLGILAKYD
VKGILNLGISMAAVMLLLPRMVRILMEGLIPISEAAKAFMQKRFQGREFYIGLDSAIAVGHPAAIATALVLVPITILLAI
ILPGNHVLPFGDLATIPFMVVMVVPVTKGNVFRSILIGTIVIGVGLWIATNVAPLFTQVAAEAAFKFPTGATEISSICDG
ANPLTWVILQIMRLF
>Mature_414_residues
SIIKYILDLGATVMLPIIIFLLALILGEKPGRAFRSALTIGIGFVGINLVIGLLVNNLGPAAQAMVEHMGVHLNVIDVGW
PASAAIAFASKVGAFVIPIGLLVNIIMLATRLTKTVNVDLWNYWHFAFTGALVTAATGSLTWGLVAAAINAAIVLLLADW
TAKMVQDFYGLPGISLPHGFSAAYVPIAIPLNKLIDKIPVINKIEADTDTINKRFGIFGEPIVIGLILGVVLGILAKYDV
KGILNLGISMAAVMLLLPRMVRILMEGLIPISEAAKAFMQKRFQGREFYIGLDSAIAVGHPAAIATALVLVPITILLAII
LPGNHVLPFGDLATIPFMVVMVVPVTKGNVFRSILIGTIVIGVGLWIATNVAPLFTQVAAEAAFKFPTGATEISSICDGA
NPLTWVILQIMRLF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=410, Percent_Identity=49.0243902439024, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1790758, Length=410, Percent_Identity=44.390243902439, Blast_Score=355, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 44079; Mature: 43948

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIKYILDLGATVMLPIIIFLLALILGEKPGRAFRSALTIGIGFVGINLVIGLLVNNLG
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAAQAMVEHMGVHLNVIDVGWPASAAIAFASKVGAFVIPIGLLVNIIMLATRLTKTVNVD
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LWNYWHFAFTGALVTAATGSLTWGLVAAAINAAIVLLLADWTAKMVQDFYGLPGISLPHG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FSAAYVPIAIPLNKLIDKIPVINKIEADTDTINKRFGIFGEPIVIGLILGVVLGILAKYD
CCCEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VKGILNLGISMAAVMLLLPRMVRILMEGLIPISEAAKAFMQKRFQGREFYIGLDSAIAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHCC
HPAAIATALVLVPITILLAIILPGNHVLPFGDLATIPFMVVMVVPVTKGNVFRSILIGTI
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VIGVGLWIATNVAPLFTQVAAEAAFKFPTGATEISSICDGANPLTWVILQIMRLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SIIKYILDLGATVMLPIIIFLLALILGEKPGRAFRSALTIGIGFVGINLVIGLLVNNLG
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAAQAMVEHMGVHLNVIDVGWPASAAIAFASKVGAFVIPIGLLVNIIMLATRLTKTVNVD
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LWNYWHFAFTGALVTAATGSLTWGLVAAAINAAIVLLLADWTAKMVQDFYGLPGISLPHG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FSAAYVPIAIPLNKLIDKIPVINKIEADTDTINKRFGIFGEPIVIGLILGVVLGILAKYD
CCCEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VKGILNLGISMAAVMLLLPRMVRILMEGLIPISEAAKAFMQKRFQGREFYIGLDSAIAVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHCC
HPAAIATALVLVPITILLAIILPGNHVLPFGDLATIPFMVVMVVPVTKGNVFRSILIGTI
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VIGVGLWIATNVAPLFTQVAAEAAFKFPTGATEISSICDGANPLTWVILQIMRLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]