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The map label for this gene is HypE [H]

Identifier: 20806663

GI number: 20806663

Start: 134409

End: 135464

Strand: Direct

Name: HypE [H]

Synonym: TTE0134

Alternate gene names: 20806663

Gene position: 134409-135464 (Clockwise)

Preceding gene: 20806662

Following gene: 20806664

Centisome position: 5.0

GC content: 41.95

Gene sequence:

>1056_bases
TTGCATGGTGTCTTCGGAAGGGTCCTGTGCAGCGTTTTACAAGTATGGCGCATAAGAGGTGATTTAATGGAAAGGGTGTT
ATTGTCCCACGGTGGCGGCGGGACAATGATGGAAAAGTTAATTGAAGAAGTGTTTGCTGATGCCTTTGACAATGAATATA
TAAGAGCAATGGAAGATGCTGCTCTTCTTTTTGGCAACATAACACTTACAACAGACAGCTTCACAGTAAAACCTCTTTTT
TTCCCAGGAGGTGACATAGGAAAGCTTGCAGTGTGCGGCACTGTAAATGATGCTTCTATGAGGGGGGCAAAGCCTTTGTT
TTTAACCGCTGCTTTCATAATAGAAGAAGGTTTTCCTGTAGAAGACTTAAAAAAAATTGTGAAGTCAATGGCAGAGGCAG
CCAAAGAAGCTGGAGTGAAAATTGTTGCAGGAGACACCAAAGTGGTTGAAAAAGGCAGTGTAGATAGAATTTTTATAAAC
ACTTCAGGGATTGGGGTGCTTTATGAGGGAGCAAATGTGTCGATAAAAAATGCCAAACCGGGAGATATAGTTTTAATCTC
TGGAACTATAGGGGACCATGGGATGGCTGTAATGAGCGCAAGAGAGGAACTTCAATTTGACACTCCTATTTTTTCCGATG
TTGCTCCTTTAAACGGTCTTATTGAGAAGCTTATGACTTTGGGGGAGGCTATAAAGGTTTTAAGAGACCCTACGAGGGGT
GGAGTGGCGGAAGTTTTGTACGAAATTTCCAAGATGAGTGGGGTGGGAATAAAGATATACGAGGAGAAGCTGCCTGTTAA
AGAAAGTGTTAAATCTGCCTGTGAGTTTATGGGCATTGACTTTTTGCACCTTGCCAATGAGGGGAAAGTGGTTGTAGTTG
TAGAAAGAGATTACGCAGAAAAAGCGTTGGAGATTATGAAGTCCCATGAATATGGCAAAGATGCAGAGATAATAGGAGAG
GTCAATGACTCAAAACTTGTGACGATTAACACAATTTACGGCACATCAAGGATTGTAGATAGACCTATAGGGGAATTACT
GCCCAGGATATGTTAG

Upstream 100 bases:

>100_bases
TAAAGGGATGTAGATGCGGAGATGTTCTAAAAGGGCGCATATATCCAAATGAATGTCCGCTATTTGGTAGAGTCTGCACC
CCAGACAATCCGGTTGGGCC

Downstream 100 bases:

>100_bases
ATGAGTTCAAGATAGAGATATTTTCCATTTCTTATTGAAGTAACCATGTAAATTGTGATAGAATAATGTAAACATTAATT
GGTTTTACGGAATATGGGGG

Product: hydrogenase maturation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MHGVFGRVLCSVLQVWRIRGDLMERVLLSHGGGGTMMEKLIEEVFADAFDNEYIRAMEDAALLFGNITLTTDSFTVKPLF
FPGGDIGKLAVCGTVNDASMRGAKPLFLTAAFIIEEGFPVEDLKKIVKSMAEAAKEAGVKIVAGDTKVVEKGSVDRIFIN
TSGIGVLYEGANVSIKNAKPGDIVLISGTIGDHGMAVMSAREELQFDTPIFSDVAPLNGLIEKLMTLGEAIKVLRDPTRG
GVAEVLYEISKMSGVGIKIYEEKLPVKESVKSACEFMGIDFLHLANEGKVVVVVERDYAEKALEIMKSHEYGKDAEIIGE
VNDSKLVTINTIYGTSRIVDRPIGELLPRIC

Sequences:

>Translated_351_residues
MHGVFGRVLCSVLQVWRIRGDLMERVLLSHGGGGTMMEKLIEEVFADAFDNEYIRAMEDAALLFGNITLTTDSFTVKPLF
FPGGDIGKLAVCGTVNDASMRGAKPLFLTAAFIIEEGFPVEDLKKIVKSMAEAAKEAGVKIVAGDTKVVEKGSVDRIFIN
TSGIGVLYEGANVSIKNAKPGDIVLISGTIGDHGMAVMSAREELQFDTPIFSDVAPLNGLIEKLMTLGEAIKVLRDPTRG
GVAEVLYEISKMSGVGIKIYEEKLPVKESVKSACEFMGIDFLHLANEGKVVVVVERDYAEKALEIMKSHEYGKDAEIIGE
VNDSKLVTINTIYGTSRIVDRPIGELLPRIC
>Mature_351_residues
MHGVFGRVLCSVLQVWRIRGDLMERVLLSHGGGGTMMEKLIEEVFADAFDNEYIRAMEDAALLFGNITLTTDSFTVKPLF
FPGGDIGKLAVCGTVNDASMRGAKPLFLTAAFIIEEGFPVEDLKKIVKSMAEAAKEAGVKIVAGDTKVVEKGSVDRIFIN
TSGIGVLYEGANVSIKNAKPGDIVLISGTIGDHGMAVMSAREELQFDTPIFSDVAPLNGLIEKLMTLGEAIKVLRDPTRG
GVAEVLYEISKMSGVGIKIYEEKLPVKESVKSACEFMGIDFLHLANEGKVVVVVERDYAEKALEIMKSHEYGKDAEIIGE
VNDSKLVTINTIYGTSRIVDRPIGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=46.2908011869436, Blast_Score=321, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 38050; Mature: 38050

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGVFGRVLCSVLQVWRIRGDLMERVLLSHGGGGTMMEKLIEEVFADAFDNEYIRAMEDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALLFGNITLTTDSFTVKPLFFPGGDIGKLAVCGTVNDASMRGAKPLFLTAAFIIEEGFPV
HHEEEEEEEEECCEEEEEEECCCCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHCCCCH
EDLKKIVKSMAEAAKEAGVKIVAGDTKVVEKGSVDRIFINTSGIGVLYEGANVSIKNAKP
HHHHHHHHHHHHHHHHCCEEEEECCCEEECCCCCCEEEEECCCCEEEEECCCEEECCCCC
GDIVLISGTIGDHGMAVMSAREELQFDTPIFSDVAPLNGLIEKLMTLGEAIKVLRDPTRG
CCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVAEVLYEISKMSGVGIKIYEEKLPVKESVKSACEFMGIDFLHLANEGKVVVVVERDYAE
CHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCHHH
KALEIMKSHEYGKDAEIIGEVNDSKLVTINTIYGTSRIVDRPIGELLPRIC
HHHHHHHHCCCCCCCCEEEECCCCEEEEEEEECCCHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MHGVFGRVLCSVLQVWRIRGDLMERVLLSHGGGGTMMEKLIEEVFADAFDNEYIRAMEDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALLFGNITLTTDSFTVKPLFFPGGDIGKLAVCGTVNDASMRGAKPLFLTAAFIIEEGFPV
HHEEEEEEEEECCEEEEEEECCCCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHCCCCH
EDLKKIVKSMAEAAKEAGVKIVAGDTKVVEKGSVDRIFINTSGIGVLYEGANVSIKNAKP
HHHHHHHHHHHHHHHHCCEEEEECCCEEECCCCCCEEEEECCCCEEEEECCCEEECCCCC
GDIVLISGTIGDHGMAVMSAREELQFDTPIFSDVAPLNGLIEKLMTLGEAIKVLRDPTRG
CCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVAEVLYEISKMSGVGIKIYEEKLPVKESVKSACEFMGIDFLHLANEGKVVVVVERDYAE
CHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCHHH
KALEIMKSHEYGKDAEIIGEVNDSKLVTINTIYGTSRIVDRPIGELLPRIC
HHHHHHHHCCCCCCCCEEEECCCCEEEEEEEECCCHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8326860 [H]