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The map label for this gene is HypD [H]

Identifier: 20806662

GI number: 20806662

Start: 133402

End: 134463

Strand: Direct

Name: HypD [H]

Synonym: TTE0133

Alternate gene names: 20806662

Gene position: 133402-134463 (Clockwise)

Preceding gene: 20806661

Following gene: 20806663

Centisome position: 4.96

GC content: 41.71

Gene sequence:

>1062_bases
ATGATGCAGCAGAGGGAAATAGTTGAAAAAGCCAAAAAAGCCATTGAAACACTAAATCCGGGTATCCCTTTTAACATAAT
GGAAGTGTGTGGATCTCACACGATGGCAATTTCAAAATTTGGCTTAAGGCAGGTTCTCCCTAAAAACATAAGGCTCATAT
CAGGACCCGGGTGTCCCGTGTGCGTGACTGCCCAGAACGAAATAGACGCAGTGATAGAGCTTTCAAATAAAAATATAGTG
ATTGCCACTTTTGGGGATTTAATAAGAGTTCCAGGGAATAAGTCCTCCCTTCAGAAGGAAAGAGCTAAAGGGAAAGAGGT
AAGAGTGTTTTACTCTCCTTTGGACGCTTTGAAGTACGCAGAGGAGAATCCGCAAAAGGAAGTTGTCTTCATAGGTATAG
GCTTTGAGACCACTGTCCCTACAGTGGCTTTGACGATAAAAGAGGCAAAAGAGAGAAAAATAAAAAATTACAGTGTGTAT
TCGCTTCACAAGACAATGCCTGAAGCCTTAAGAGCTCTTCTGGTAGGGGGTTCTAATGTTCAGGGATTTTTACTGCCGGG
ACATGTGAGTGCAATAACAGGAAGCCGCATATATGAGTTTTTGCCAAGAGAGTTTGGAGTAGGTGGTGTGATATCAGGTT
TTGAGGCAGAAGATATTTTGATGAGCATAGTAATGCTTTTAAAAAATTATAAAAATCCTACAATTGAGATCCAGTACAAA
AGGGTTGTGAAAGAAGAAGGAAATATTGAAGCGCAGAAGATAATTGAAGAAGTTTTTGAACCCTGTGACAGCACATGGAG
AGGGCTTGGCGAGATAAAAGGTTCAGGCCTTAAGATAAGGGACAAATACAAAGACTTTGATGCAGCCTTAAAATTTGACA
TAAAGCCTGTTGGAGATGAAATAGAGATAAAGGGATGTAGATGCGGAGATGTTCTAAAAGGGCGCATATATCCAAATGAA
TGTCCGCTATTTGGTAGAGTCTGCACCCCAGACAATCCGGTTGGGCCTTGCATGGTGTCTTCGGAAGGGTCCTGTGCAGC
GTTTTACAAGTATGGCGCATAA

Upstream 100 bases:

>100_bases
GACTATGTAATGGTGCACGCAGGAGTTGCAATAAGCATAGTGGATAAAGAAGAGGCAGAAGCACAGAGAGGGCTCTGGAA
TGAGCTTATGGAGGTTTTAA

Downstream 100 bases:

>100_bases
GAGGTGATTTAATGGAAAGGGTGTTATTGTCCCACGGTGGCGGCGGGACAATGATGGAAAAGTTAATTGAAGAAGTGTTT
GCTGATGCCTTTGACAATGA

Product: hydrogenase maturation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MMQQREIVEKAKKAIETLNPGIPFNIMEVCGSHTMAISKFGLRQVLPKNIRLISGPGCPVCVTAQNEIDAVIELSNKNIV
IATFGDLIRVPGNKSSLQKERAKGKEVRVFYSPLDALKYAEENPQKEVVFIGIGFETTVPTVALTIKEAKERKIKNYSVY
SLHKTMPEALRALLVGGSNVQGFLLPGHVSAITGSRIYEFLPREFGVGGVISGFEAEDILMSIVMLLKNYKNPTIEIQYK
RVVKEEGNIEAQKIIEEVFEPCDSTWRGLGEIKGSGLKIRDKYKDFDAALKFDIKPVGDEIEIKGCRCGDVLKGRIYPNE
CPLFGRVCTPDNPVGPCMVSSEGSCAAFYKYGA

Sequences:

>Translated_353_residues
MMQQREIVEKAKKAIETLNPGIPFNIMEVCGSHTMAISKFGLRQVLPKNIRLISGPGCPVCVTAQNEIDAVIELSNKNIV
IATFGDLIRVPGNKSSLQKERAKGKEVRVFYSPLDALKYAEENPQKEVVFIGIGFETTVPTVALTIKEAKERKIKNYSVY
SLHKTMPEALRALLVGGSNVQGFLLPGHVSAITGSRIYEFLPREFGVGGVISGFEAEDILMSIVMLLKNYKNPTIEIQYK
RVVKEEGNIEAQKIIEEVFEPCDSTWRGLGEIKGSGLKIRDKYKDFDAALKFDIKPVGDEIEIKGCRCGDVLKGRIYPNE
CPLFGRVCTPDNPVGPCMVSSEGSCAAFYKYGA
>Mature_353_residues
MMQQREIVEKAKKAIETLNPGIPFNIMEVCGSHTMAISKFGLRQVLPKNIRLISGPGCPVCVTAQNEIDAVIELSNKNIV
IATFGDLIRVPGNKSSLQKERAKGKEVRVFYSPLDALKYAEENPQKEVVFIGIGFETTVPTVALTIKEAKERKIKNYSVY
SLHKTMPEALRALLVGGSNVQGFLLPGHVSAITGSRIYEFLPREFGVGGVISGFEAEDILMSIVMLLKNYKNPTIEIQYK
RVVKEEGNIEAQKIIEEVFEPCDSTWRGLGEIKGSGLKIRDKYKDFDAALKFDIKPVGDEIEIKGCRCGDVLKGRIYPNE
CPLFGRVCTPDNPVGPCMVSSEGSCAAFYKYGA

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=337, Percent_Identity=46.5875370919881, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 38975; Mature: 38975

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQQREIVEKAKKAIETLNPGIPFNIMEVCGSHTMAISKFGLRQVLPKNIRLISGPGCPV
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCE
CVTAQNEIDAVIELSNKNIVIATFGDLIRVPGNKSSLQKERAKGKEVRVFYSPLDALKYA
EEECCCCCEEEEEECCCCEEEEECCCEEECCCCHHHHHHHHHCCCEEEEEECCHHHHHHH
EENPQKEVVFIGIGFETTVPTVALTIKEAKERKIKNYSVYSLHKTMPEALRALLVGGSNV
CCCCCCEEEEEEECCCCCCCEEEEEEEHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCC
QGFLLPGHVSAITGSRIYEFLPREFGVGGVISGFEAEDILMSIVMLLKNYKNPTIEIQYK
CEEEECCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEEEEEH
RVVKEEGNIEAQKIIEEVFEPCDSTWRGLGEIKGSGLKIRDKYKDFDAALKFDIKPVGDE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCEEEEECEECCCC
IEIKGCRCGDVLKGRIYPNECPLFGRVCTPDNPVGPCMVSSEGSCAAFYKYGA
EEEECCCCCCCEECCCCCCCCCCCEEECCCCCCCCCEEECCCCCEEEEEECCC
>Mature Secondary Structure
MMQQREIVEKAKKAIETLNPGIPFNIMEVCGSHTMAISKFGLRQVLPKNIRLISGPGCPV
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCE
CVTAQNEIDAVIELSNKNIVIATFGDLIRVPGNKSSLQKERAKGKEVRVFYSPLDALKYA
EEECCCCCEEEEEECCCCEEEEECCCEEECCCCHHHHHHHHHCCCEEEEEECCHHHHHHH
EENPQKEVVFIGIGFETTVPTVALTIKEAKERKIKNYSVYSLHKTMPEALRALLVGGSNV
CCCCCCEEEEEEECCCCCCCEEEEEEEHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCC
QGFLLPGHVSAITGSRIYEFLPREFGVGGVISGFEAEDILMSIVMLLKNYKNPTIEIQYK
CEEEECCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCEEEEEEH
RVVKEEGNIEAQKIIEEVFEPCDSTWRGLGEIKGSGLKIRDKYKDFDAALKFDIKPVGDE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCEEEEECEECCCC
IEIKGCRCGDVLKGRIYPNECPLFGRVCTPDNPVGPCMVSSEGSCAAFYKYGA
EEEECCCCCCCEECCCCCCCCCCCEEECCCCCCCCCEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]