BacMap

Definition	Thermoanaerobacter tengcongensis MB4, complete genome.
Accession	NC_003869
Length	2,689,445

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The map label for this gene is HflB [H]

Identifier: 20806651

GI number: 20806651

Start: 123281

End: 124759

Strand: Direct

Name: HflB [H]

Synonym: TTE0122

Alternate gene names: 20806651

Gene position: 123281-124759 (Clockwise)

Preceding gene: 20806650

Following gene: 20806652

Centisome position: 4.58

GC content: 40.16

Gene sequence:

>1479_bases
ATGGTAAGAGAGATTTTGCTTGGGATAGCTATTGCTTTTACAATATTTGCTGCGTTTTTGGGTATTAATGTGATGCCTAT
TGTCTTTTTGATGGCTGCTTTTCTGCTTTTGAGCCATCTTATAGAAAATAGAGGTTTAGTTCCTGCGAATAAAAATATTG
TAAATCCAGAGTCGGAAGTTTCTTTTGAGGATATTGGAGGGCAAAATACGGCCATTTCTGAATTGAAAGAGGCTTTAGAT
TTTGTTGTAAATAGAGAAAAAATAGCTCAGATGGGAATACGACCTATCAAGGGGATATTGCTTATTGGGCCTCCTGGAAC
GGGGAAAACTTTGCTTGCTAAAGCTGCTGCAAAATACACGAATTCCAGTTTTATAGCTACTTCTGGCAGCGAGTTCATAG
AGATGTATGCGGGAGTTGGAGCTCAAAGAGTAAGGCATCTTTTTGAAACAGCAAAAAGCTTAGCCAAAAAAGAAGGGAAA
AACAGTGCTATAATTTTCATAGACGAAATTGACATATTGGGGGCGAAAAGAGGTACTCATGAAAGCCACCACGAATACGA
TCAGACCCTTAATCAGCTTTTAGTGGAAATGGATGGAATCAAAAATAATGGGGATGTAAATATTTTGGTCATAGCTGCGA
CTAACAGACCGGACCTTCTGGACCCTGCGCTTTTAAGGCCAGGGCGCTTTGACAGACAGGTTGTGGTGGACCTTCCTGAC
AAAAACGGCAGACTTCAGATTTTAAAGATTCACACAAAGAATAAGCCTTTAGGAGAGGATGTGAATTTGGAGGAAATAGC
AGAGAGCACTTTTGGTTTTTCTGGAGCTCATCTAGAAAATTTGTGCAATGAAGCTGCAATTTTGGCTTTAAGAGACGGTT
CCCCTTCAATTTTGCAAAAGCATTTCAAAGAGGCTATAGATAAAGTTATACTGGGGGAGAAGAGTGACAGAAAGCCTACA
GAGGAGGAACTTTACAGAATTGCTGTTCACGAAGCAGGACATGCTATAGTTGGAGAAGAAGTAAACCCAGGGTCTGTTGC
TGTAATTACAATTGTGCCAAGAGGAAGGGCATTAGGATTTGTAAGACAAGCAGAAAAAAAGGACCTCCTCATATACACCA
AGGAACAGCTGGAAAAGGACATAATGGTGGCTTTAGGAGGTACAGTTGCAGAGGTTTTGGTTTTAGGGGGGAGGAGCACG
GGTTCTGCCAATGACTTTGAGCAGGCTGTGGATATTGCTAAAAAAATCGTGTTTACAGGGCTTTCTGATCTGGGGATTGT
GAGTAAAGAGGATATTTCAAAAGAAAAAGTGAATGAGGAAGTAAACAAGATTGTAAAAAATTTAGAGGATAAGGTGAAGG
AGATCCTCGAAAGAAGGCTTGAAAAGTTAAAAGAAGTGGCTGAACTTCTTAAGAAAGAAGAAGCTATTTCGGGGGAAAAG
TTGAGAGAGATTTTGAATAAGGAGGAAGTTTTGGCTTAA

Upstream 100 bases:

>100_bases
ATAGACGAGCACAATATTTACATCGATTTGAGGGATGATTCCCATTATCTTTACAAGGTAATTGCGCGGTGACTGCTTGA
AAAGCCAAGGGGGAATTTGT

Downstream 100 bases:

>100_bases
GTAAAGCTGTTTTTTTACTCTCGTTTGTTAAAATAATAACAACTATTTTGTGATAAAAGTTCTTTATTATTATTGACTTT
GTAGTTTTAAAACTTTATAA

Product: ATP-dependent Zn protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MVREILLGIAIAFTIFAAFLGINVMPIVFLMAAFLLLSHLIENRGLVPANKNIVNPESEVSFEDIGGQNTAISELKEALD
FVVNREKIAQMGIRPIKGILLIGPPGTGKTLLAKAAAKYTNSSFIATSGSEFIEMYAGVGAQRVRHLFETAKSLAKKEGK
NSAIIFIDEIDILGAKRGTHESHHEYDQTLNQLLVEMDGIKNNGDVNILVIAATNRPDLLDPALLRPGRFDRQVVVDLPD
KNGRLQILKIHTKNKPLGEDVNLEEIAESTFGFSGAHLENLCNEAAILALRDGSPSILQKHFKEAIDKVILGEKSDRKPT
EEELYRIAVHEAGHAIVGEEVNPGSVAVITIVPRGRALGFVRQAEKKDLLIYTKEQLEKDIMVALGGTVAEVLVLGGRST
GSANDFEQAVDIAKKIVFTGLSDLGIVSKEDISKEKVNEEVNKIVKNLEDKVKEILERRLEKLKEVAELLKKEEAISGEK
LREILNKEEVLA

Sequences:

>Translated_492_residues
MVREILLGIAIAFTIFAAFLGINVMPIVFLMAAFLLLSHLIENRGLVPANKNIVNPESEVSFEDIGGQNTAISELKEALD
FVVNREKIAQMGIRPIKGILLIGPPGTGKTLLAKAAAKYTNSSFIATSGSEFIEMYAGVGAQRVRHLFETAKSLAKKEGK
NSAIIFIDEIDILGAKRGTHESHHEYDQTLNQLLVEMDGIKNNGDVNILVIAATNRPDLLDPALLRPGRFDRQVVVDLPD
KNGRLQILKIHTKNKPLGEDVNLEEIAESTFGFSGAHLENLCNEAAILALRDGSPSILQKHFKEAIDKVILGEKSDRKPT
EEELYRIAVHEAGHAIVGEEVNPGSVAVITIVPRGRALGFVRQAEKKDLLIYTKEQLEKDIMVALGGTVAEVLVLGGRST
GSANDFEQAVDIAKKIVFTGLSDLGIVSKEDISKEKVNEEVNKIVKNLEDKVKEILERRLEKLKEVAELLKKEEAISGEK
LREILNKEEVLA
>Mature_492_residues
MVREILLGIAIAFTIFAAFLGINVMPIVFLMAAFLLLSHLIENRGLVPANKNIVNPESEVSFEDIGGQNTAISELKEALD
FVVNREKIAQMGIRPIKGILLIGPPGTGKTLLAKAAAKYTNSSFIATSGSEFIEMYAGVGAQRVRHLFETAKSLAKKEGK
NSAIIFIDEIDILGAKRGTHESHHEYDQTLNQLLVEMDGIKNNGDVNILVIAATNRPDLLDPALLRPGRFDRQVVVDLPD
KNGRLQILKIHTKNKPLGEDVNLEEIAESTFGFSGAHLENLCNEAAILALRDGSPSILQKHFKEAIDKVILGEKSDRKPT
EEELYRIAVHEAGHAIVGEEVNPGSVAVITIVPRGRALGFVRQAEKKDLLIYTKEQLEKDIMVALGGTVAEVLVLGGRST
GSANDFEQAVDIAKKIVFTGLSDLGIVSKEDISKEKVNEEVNKIVKNLEDKVKEILERRLEKLKEVAELLKKEEAISGEK
LREILNKEEVLA

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=461, Percent_Identity=40.997830802603, Blast_Score=295, Evalue=7e-80,
Organism=Homo sapiens, GI7657689, Length=438, Percent_Identity=39.7260273972603, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI21327685, Length=438, Percent_Identity=39.7260273972603, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI4507173, Length=451, Percent_Identity=37.0288248337029, Blast_Score=265, Evalue=9e-71,
Organism=Homo sapiens, GI21361144, Length=259, Percent_Identity=41.6988416988417, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4506209, Length=260, Percent_Identity=40.3846153846154, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI24430151, Length=268, Percent_Identity=40.6716417910448, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI24497435, Length=258, Percent_Identity=43.0232558139535, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI6005942, Length=236, Percent_Identity=44.0677966101695, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI5729991, Length=271, Percent_Identity=41.3284132841328, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI24430155, Length=271, Percent_Identity=41.3284132841328, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI195539395, Length=268, Percent_Identity=41.4179104477612, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI89064750, Length=271, Percent_Identity=41.3284132841328, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI157671927, Length=254, Percent_Identity=40.9448818897638, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI229577436, Length=272, Percent_Identity=37.5, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI45643125, Length=271, Percent_Identity=40.2214022140221, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI45643123, Length=271, Percent_Identity=40.2214022140221, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI24497618, Length=260, Percent_Identity=39.2307692307692, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI153792536, Length=266, Percent_Identity=37.9699248120301, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI4505725, Length=250, Percent_Identity=38, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI5901990, Length=246, Percent_Identity=37.8048780487805, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI156564401, Length=250, Percent_Identity=40.8, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI14149767, Length=246, Percent_Identity=36.5853658536585, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI62177112, Length=246, Percent_Identity=36.5853658536585, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI310125282, Length=250, Percent_Identity=40.4, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI310125280, Length=236, Percent_Identity=41.5254237288136, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI40806170, Length=247, Percent_Identity=38.8663967611336, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI11875211, Length=247, Percent_Identity=38.8663967611336, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI194018488, Length=235, Percent_Identity=40.4255319148936, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI31742536, Length=234, Percent_Identity=36.3247863247863, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI112789543, Length=234, Percent_Identity=36.3247863247863, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI7019569, Length=256, Percent_Identity=33.203125, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI31377644, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI40806173, Length=143, Percent_Identity=48.2517482517483, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226371754, Length=286, Percent_Identity=32.8671328671329, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI17865802, Length=235, Percent_Identity=35.7446808510638, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI64084766, Length=256, Percent_Identity=27.734375, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI116292174, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI75677353, Length=215, Percent_Identity=30.2325581395349, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI283436224, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI283436222, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI283436220, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789568, Length=505, Percent_Identity=37.4257425742574, Blast_Score=309, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI71994521, Length=462, Percent_Identity=38.961038961039, Blast_Score=284, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17554264, Length=441, Percent_Identity=37.4149659863946, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI115534323, Length=468, Percent_Identity=34.8290598290598, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17508701, Length=249, Percent_Identity=42.1686746987952, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17563248, Length=262, Percent_Identity=41.2213740458015, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17563250, Length=268, Percent_Identity=41.7910447761194, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17554786, Length=258, Percent_Identity=43.0232558139535, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI25144281, Length=258, Percent_Identity=43.0232558139535, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI25144278, Length=258, Percent_Identity=43.0232558139535, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=257, Percent_Identity=41.2451361867704, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71987364, Length=267, Percent_Identity=39.3258426966292, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71987372, Length=267, Percent_Identity=39.3258426966292, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17532375, Length=237, Percent_Identity=43.0379746835443, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17531535, Length=236, Percent_Identity=42.7966101694915, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=255, Percent_Identity=38.8235294117647, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17537217, Length=279, Percent_Identity=39.7849462365591, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17554784, Length=261, Percent_Identity=38.6973180076628, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI133901658, Length=253, Percent_Identity=41.897233201581, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI133901662, Length=253, Percent_Identity=41.897233201581, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI193206114, Length=347, Percent_Identity=33.7175792507205, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI133931034, Length=347, Percent_Identity=33.7175792507205, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193206116, Length=347, Percent_Identity=33.7175792507205, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25153574, Length=236, Percent_Identity=40.2542372881356, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193209502, Length=235, Percent_Identity=40.4255319148936, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI32563584, Length=240, Percent_Identity=37.9166666666667, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17508421, Length=240, Percent_Identity=37.9166666666667, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=254, Percent_Identity=35.0393700787402, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17562804, Length=267, Percent_Identity=34.8314606741573, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17560432, Length=244, Percent_Identity=35.655737704918, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17541224, Length=227, Percent_Identity=34.8017621145374, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541226, Length=227, Percent_Identity=34.8017621145374, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI86561515, Length=241, Percent_Identity=35.2697095435685, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17570397, Length=154, Percent_Identity=43.5064935064935, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32566590, Length=154, Percent_Identity=43.5064935064935, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320854, Length=455, Percent_Identity=40.4395604395604, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6325281, Length=472, Percent_Identity=38.3474576271186, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6323736, Length=499, Percent_Identity=36.0721442885772, Blast_Score=280, Evalue=4e-76,
Organism=Saccharomyces cerevisiae, GI6322704, Length=264, Percent_Identity=42.0454545454545, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324691, Length=252, Percent_Identity=43.2539682539683, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320197, Length=254, Percent_Identity=42.5196850393701, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321390, Length=286, Percent_Identity=38.1118881118881, Blast_Score=190, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6320077, Length=239, Percent_Identity=42.6778242677824, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324833, Length=258, Percent_Identity=43.4108527131783, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321709, Length=256, Percent_Identity=38.28125, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6320602, Length=255, Percent_Identity=38.4313725490196, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324000, Length=234, Percent_Identity=39.7435897435897, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6322651, Length=241, Percent_Identity=39.8340248962656, Blast_Score=160, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6323429, Length=258, Percent_Identity=39.1472868217054, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322994, Length=238, Percent_Identity=38.655462184874, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6319554, Length=266, Percent_Identity=37.9699248120301, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6325183, Length=248, Percent_Identity=38.3064516129032, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321465, Length=246, Percent_Identity=36.5853658536585, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6325431, Length=255, Percent_Identity=34.9019607843137, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=254, Percent_Identity=34.251968503937, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320583, Length=163, Percent_Identity=29.4478527607362, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24665814, Length=458, Percent_Identity=41.703056768559, Blast_Score=305, Evalue=6e-83,
Organism=Drosophila melanogaster, GI28574878, Length=458, Percent_Identity=41.703056768559, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24658770, Length=497, Percent_Identity=39.4366197183099, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24639391, Length=460, Percent_Identity=37.8260869565217, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17738151, Length=258, Percent_Identity=42.6356589147287, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24649446, Length=268, Percent_Identity=42.5373134328358, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17137738, Length=260, Percent_Identity=41.1538461538462, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24651451, Length=260, Percent_Identity=43.0769230769231, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19920408, Length=258, Percent_Identity=43.0232558139535, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24640100, Length=269, Percent_Identity=39.7769516728625, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI17137560, Length=235, Percent_Identity=42.5531914893617, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI161076488, Length=235, Percent_Identity=42.5531914893617, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI161076486, Length=235, Percent_Identity=42.5531914893617, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI18860063, Length=271, Percent_Identity=40.9594095940959, Blast_Score=185, Evalue=8e-47,
Organism=Drosophila melanogaster, GI281361487, Length=249, Percent_Identity=40.9638554216867, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24663015, Length=269, Percent_Identity=39.0334572490706, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19921202, Length=236, Percent_Identity=38.5593220338983, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24656825, Length=266, Percent_Identity=40.6015037593985, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24656820, Length=266, Percent_Identity=40.6015037593985, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24660075, Length=265, Percent_Identity=39.2452830188679, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281365776, Length=265, Percent_Identity=39.2452830188679, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI45552965, Length=265, Percent_Identity=39.2452830188679, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24652279, Length=242, Percent_Identity=37.603305785124, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281363136, Length=238, Percent_Identity=39.4957983193277, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI78707192, Length=238, Percent_Identity=39.4957983193277, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573010, Length=251, Percent_Identity=39.4422310756972, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI17864540, Length=251, Percent_Identity=39.4422310756972, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360146, Length=268, Percent_Identity=33.5820895522388, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360138, Length=268, Percent_Identity=33.5820895522388, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360142, Length=268, Percent_Identity=33.5820895522388, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357333, Length=268, Percent_Identity=33.5820895522388, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281360144, Length=268, Percent_Identity=33.5820895522388, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360140, Length=268, Percent_Identity=33.5820895522388, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360136, Length=268, Percent_Identity=33.5820895522388, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24644411, Length=268, Percent_Identity=33.5820895522388, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24644145, Length=243, Percent_Identity=34.5679012345679, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21355121, Length=237, Percent_Identity=36.2869198312236, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI45554047, Length=175, Percent_Identity=46.8571428571429, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24581396, Length=247, Percent_Identity=37.6518218623482, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI20129529, Length=243, Percent_Identity=35.3909465020576, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859657, Length=253, Percent_Identity=35.1778656126482, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571849, Length=245, Percent_Identity=38.3673469387755, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28571847, Length=245, Percent_Identity=38.3673469387755, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20129423, Length=249, Percent_Identity=32.1285140562249, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24639486, Length=295, Percent_Identity=29.4915254237288, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 53946; Mature: 53946

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVREILLGIAIAFTIFAAFLGINVMPIVFLMAAFLLLSHLIENRGLVPANKNIVNPESEV
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SFEDIGGQNTAISELKEALDFVVNREKIAQMGIRPIKGILLIGPPGTGKTLLAKAAAKYT
CHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHC
NSSFIATSGSEFIEMYAGVGAQRVRHLFETAKSLAKKEGKNSAIIFIDEIDILGAKRGTH
CCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCC
ESHHEYDQTLNQLLVEMDGIKNNGDVNILVIAATNRPDLLDPALLRPGRFDRQVVVDLPD
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCC
KNGRLQILKIHTKNKPLGEDVNLEEIAESTFGFSGAHLENLCNEAAILALRDGSPSILQK
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHCCCEEEEEECCCCHHHHHH
HFKEAIDKVILGEKSDRKPTEEELYRIAVHEAGHAIVGEEVNPGSVAVITIVPRGRALGF
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECCCCHHHH
VRQAEKKDLLIYTKEQLEKDIMVALGGTVAEVLVLGGRSTGSANDFEQAVDIAKKIVFTG
HHHHCCCCEEEEEHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
LSDLGIVSKEDISKEKVNEEVNKIVKNLEDKVKEILERRLEKLKEVAELLKKEEAISGEK
CHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LREILNKEEVLA
HHHHHHHHHCCC
>Mature Secondary Structure
MVREILLGIAIAFTIFAAFLGINVMPIVFLMAAFLLLSHLIENRGLVPANKNIVNPESEV
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SFEDIGGQNTAISELKEALDFVVNREKIAQMGIRPIKGILLIGPPGTGKTLLAKAAAKYT
CHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHC
NSSFIATSGSEFIEMYAGVGAQRVRHLFETAKSLAKKEGKNSAIIFIDEIDILGAKRGTH
CCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCC
ESHHEYDQTLNQLLVEMDGIKNNGDVNILVIAATNRPDLLDPALLRPGRFDRQVVVDLPD
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCC
KNGRLQILKIHTKNKPLGEDVNLEEIAESTFGFSGAHLENLCNEAAILALRDGSPSILQK
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHCCCEEEEEECCCCHHHHHH
HFKEAIDKVILGEKSDRKPTEEELYRIAVHEAGHAIVGEEVNPGSVAVITIVPRGRALGF
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECCCCHHHH
VRQAEKKDLLIYTKEQLEKDIMVALGGTVAEVLVLGGRSTGSANDFEQAVDIAKKIVFTG
HHHHCCCCEEEEEHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHC
LSDLGIVSKEDISKEKVNEEVNKIVKNLEDKVKEILERRLEKLKEVAELLKKEEAISGEK
CHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LREILNKEEVLA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]