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The map label for this gene is AcrR [H]

Identifier: 20806602

GI number: 20806602

Start: 77827

End: 78402

Strand: Direct

Name: AcrR [H]

Synonym: TTE0070

Alternate gene names: 20806602

Gene position: 77827-78402 (Clockwise)

Preceding gene: 20806601

Following gene: 20806603

Centisome position: 2.89

GC content: 35.59

Gene sequence:

>576_bases
ATGAGCAGTACGAAAGAGAGGATATTTAAGGCTGCTTTAGAGACTTTTTCTAAAAGAGGATTTTACAAGGCTACTATGGA
TGAGATTGCTGAGGCTGCTGGAGTTGCCAAGGGAACTCTTTATTACCATTTTAAAAGCAAGGACGATATATTGGATTTTT
TGATAGATGAGGGCATAAAGAGGTTAAAGCAACAAGCAATAGAGGAAATAAGCAAGGTGAATGGCGCAATTGAAAAACTC
AAAAGGATTGTTTTTGTTCAGACCAATTTTCTTTATAAAAATCACGATTTTATAATAGTGCTTTTGAGTCAAATATGGGG
GCACGGAGATGTTCCGCGAAGATTTAGAGAAAAACTTTCAACTTATTTGGAGATTATTGAAAAGGTAGTTAAAGAGGGAA
AGGAACAAAAACTTTTGGCGGATTGTAATGAAAAACTAGTGGCAGCGGCGTTTTTTGGCATGACAACTTCGATTCTTGCA
CTAAAAGTCATAAGAGAAGAAGAAACTGTCGATACTCAAGAAATAACTGATACAGTCTTCAATTTTGCCCTAAATGGTTT
GAAATTTTATCACTGA

Upstream 100 bases:

>100_bases
CTTGTGTTCTGAGGAAGCTTCTTTTATAACAGGTGCAAATTTGATTGTCGACGGCGGCATGACAGTAAAAATGATTTATC
TGTAGAGGAAAGGAAAGAAA

Downstream 100 bases:

>100_bases
CACCTCGAAAGAGGTGTTTTTTGTTGACTTTTAAAAGGACGGCGAATATAATATTTATTGTACTGACTGGTCAGTATAAA
TTTTAAAGTGGGGAGGGGAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSSTKERIFKAALETFSKRGFYKATMDEIAEAAGVAKGTLYYHFKSKDDILDFLIDEGIKRLKQQAIEEISKVNGAIEKL
KRIVFVQTNFLYKNHDFIIVLLSQIWGHGDVPRRFREKLSTYLEIIEKVVKEGKEQKLLADCNEKLVAAAFFGMTTSILA
LKVIREEETVDTQEITDTVFNFALNGLKFYH

Sequences:

>Translated_191_residues
MSSTKERIFKAALETFSKRGFYKATMDEIAEAAGVAKGTLYYHFKSKDDILDFLIDEGIKRLKQQAIEEISKVNGAIEKL
KRIVFVQTNFLYKNHDFIIVLLSQIWGHGDVPRRFREKLSTYLEIIEKVVKEGKEQKLLADCNEKLVAAAFFGMTTSILA
LKVIREEETVDTQEITDTVFNFALNGLKFYH
>Mature_190_residues
SSTKERIFKAALETFSKRGFYKATMDEIAEAAGVAKGTLYYHFKSKDDILDFLIDEGIKRLKQQAIEEISKVNGAIEKLK
RIVFVQTNFLYKNHDFIIVLLSQIWGHGDVPRRFREKLSTYLEIIEKVVKEGKEQKLLADCNEKLVAAAFFGMTTSILAL
KVIREEETVDTQEITDTVFNFALNGLKFYH

Specific function: Putative repressor of the mtrC gene. Controls the permeability of the cell envelope to hydrophobic compounds such as antibiotics and detergents [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21953; Mature: 21821

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTKERIFKAALETFSKRGFYKATMDEIAEAAGVAKGTLYYHFKSKDDILDFLIDEGIK
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
RLKQQAIEEISKVNGAIEKLKRIVFVQTNFLYKNHDFIIVLLSQIWGHGDVPRRFREKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCHHHHHHHH
TYLEIIEKVVKEGKEQKLLADCNEKLVAAAFFGMTTSILALKVIREEETVDTQEITDTVF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
NFALNGLKFYH
HHHHHHHHCCC
>Mature Secondary Structure 
SSTKERIFKAALETFSKRGFYKATMDEIAEAAGVAKGTLYYHFKSKDDILDFLIDEGIK
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
RLKQQAIEEISKVNGAIEKLKRIVFVQTNFLYKNHDFIIVLLSQIWGHGDVPRRFREKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCHHHHHHHH
TYLEIIEKVVKEGKEQKLLADCNEKLVAAAFFGMTTSILALKVIREEETVDTQEITDTVF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
NFALNGLKFYH
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196548 [H]