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The map label for this gene is FocA [H]

Identifier: 20806596

GI number: 20806596

Start: 71511

End: 72374

Strand: Direct

Name: FocA [H]

Synonym: TTE0064

Alternate gene names: 20806596

Gene position: 71511-72374 (Clockwise)

Preceding gene: 20806595

Following gene: 20806597

Centisome position: 2.66

GC content: 38.43

Gene sequence:

>864_bases
ATGGGTTTTAAAATGCCAAAAGACATAACAGAAGGAATGAGTAGTTTAGGAAAAGCTAAATCAGAGCTTTCTATTTCTAA
ATTGCTTGTGCTGGGGTTTTTAGGAGGAGCGTACATAGCTTTAGGAGGGCTTTTAGCAATTAGAGCGGCAGGAGCCTTGC
CTGACTCCTTTGGAAGCCTTCAAAAATTTATATTTGGAGCAGTATTTCCTTTGGGGCTTATTCTTGTGGTAATAGCGGGA
GCAGAACTGGTCACAGGAAATATGATGACACAGCCCATGGCTTATTTTGATAGAAAAATAGACTTGAAAGGCCTTTTAAA
AAACTGGACTTTTGTTTACATAGGGAACTTTATAGGTTCAGTGTTTGTCGCATATTTTTTGGCTTATAAAACGGGGCTTA
TAATGGAAGTGGCAAAAATGGGGGAAATACCAAAAGCACTCCCATGGGCTTTATATGCAGTAAAAATAGCGAACGCTAAA
GTGAGCTTATCGTGGTGGCAGGCATTTTTAAGAGGTATAGGGTGTAATTGGCTGGTCGCTTTGGCCGTGTGGATGGCCTA
TTCTGCTGAGGATATAATAGGCAAGATTTTTGCCATATGGTGGCCTATAATGGGTTTTGTCGCTATAGGCTTTGAACATT
CAGTGGCTAATATGTTTTTTATTCCTCTCGGAATATATGCAGGACAAGACCCTCTTTATGTTAATTTTGCAAAAAGTGCA
GAAGGAATACTTTTAAATGTACCTATTCTGAAAGCTACATGGGAGAATTTTATAGTAAATAATTTGATACCTGTAACTCT
AGGTAACATAGTAGGAGCGGGATTTTTTGTGGCTACAATCTACTGGTATGTATATAGAAAATAA

Upstream 100 bases:

>100_bases
TAATTTTCATTGAAGGCAAAAAGTCTCCGGCATCTTCGGAGACTTTTTAAATTGTTCAAAATTGTGATATCGTTTACTGT
ATTTAAGCTGGGGGGATTTT

Downstream 100 bases:

>100_bases
GTGGTACTTTATAAAGTGCCACTTATTTTGTAAATATTTTACTTAGGAAGGCTTGACATTCCACATTTTCTCAATTATAA
TATCTTATAGATTAATTTTA

Product: formate/nitrate transporter

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGFKMPKDITEGMSSLGKAKSELSISKLLVLGFLGGAYIALGGLLAIRAAGALPDSFGSLQKFIFGAVFPLGLILVVIAG
AELVTGNMMTQPMAYFDRKIDLKGLLKNWTFVYIGNFIGSVFVAYFLAYKTGLIMEVAKMGEIPKALPWALYAVKIANAK
VSLSWWQAFLRGIGCNWLVALAVWMAYSAEDIIGKIFAIWWPIMGFVAIGFEHSVANMFFIPLGIYAGQDPLYVNFAKSA
EGILLNVPILKATWENFIVNNLIPVTLGNIVGAGFFVATIYWYVYRK

Sequences:

>Translated_287_residues
MGFKMPKDITEGMSSLGKAKSELSISKLLVLGFLGGAYIALGGLLAIRAAGALPDSFGSLQKFIFGAVFPLGLILVVIAG
AELVTGNMMTQPMAYFDRKIDLKGLLKNWTFVYIGNFIGSVFVAYFLAYKTGLIMEVAKMGEIPKALPWALYAVKIANAK
VSLSWWQAFLRGIGCNWLVALAVWMAYSAEDIIGKIFAIWWPIMGFVAIGFEHSVANMFFIPLGIYAGQDPLYVNFAKSA
EGILLNVPILKATWENFIVNNLIPVTLGNIVGAGFFVATIYWYVYRK
>Mature_286_residues
GFKMPKDITEGMSSLGKAKSELSISKLLVLGFLGGAYIALGGLLAIRAAGALPDSFGSLQKFIFGAVFPLGLILVVIAGA
ELVTGNMMTQPMAYFDRKIDLKGLLKNWTFVYIGNFIGSVFVAYFLAYKTGLIMEVAKMGEIPKALPWALYAVKIANAKV
SLSWWQAFLRGIGCNWLVALAVWMAYSAEDIIGKIFAIWWPIMGFVAIGFEHSVANMFFIPLGIYAGQDPLYVNFAKSAE
GILLNVPILKATWENFIVNNLIPVTLGNIVGAGFFVATIYWYVYRK

Specific function: May act as a formate transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=288, Percent_Identity=33.6805555555556, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788837, Length=283, Percent_Identity=31.8021201413428, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87082249, Length=254, Percent_Identity=31.8897637795276, Blast_Score=101, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321779, Length=269, Percent_Identity=29.368029739777, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 31429; Mature: 31298

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFKMPKDITEGMSSLGKAKSELSISKLLVLGFLGGAYIALGGLLAIRAAGALPDSFGSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QKFIFGAVFPLGLILVVIAGAELVTGNMMTQPMAYFDRKIDLKGLLKNWTFVYIGNFIGS
HHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
VFVAYFLAYKTGLIMEVAKMGEIPKALPWALYAVKIANAKVSLSWWQAFLRGIGCNWLVA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCEEEHHHHHHHHHHCCHHHHHH
LAVWMAYSAEDIIGKIFAIWWPIMGFVAIGFEHSVANMFFIPLGIYAGQDPLYVNFAKSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCC
EGILLNVPILKATWENFIVNNLIPVTLGNIVGAGFFVATIYWYVYRK
CCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9006048 [H]