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The map label for this gene is MurE

Identifier: 20806550

GI number: 20806550

Start: 7924

End: 9276

Strand: Reverse

Name: MurE

Synonym: TTE0008

Alternate gene names: NA

Gene position: 9276-7924 (Counterclockwise)

Preceding gene: 20806551

Following gene: 20806549

Centisome position: 0.34

GC content: 35.18

Gene sequence:

>1353_bases
GTGAAAGGGCTAGGGGTAGCAATAGGAAAATTAGTAAACATCTCCTGTAAAATTACAGGCAAAGGAGGAACTTCATTACC
AGGTAAAATTGCCCTCATGGCAGATGACCACTTAATAAAAAAGCTGATAGAACCTTTAAAAGAAAACAAAGTAATAGTCA
CCGGAACTAATGGAAAAACTACTACTTCAGGGCTTATAGCTCACCTTCTTTCCTATTCCGGAAGAAAGGTAGTTCACAAC
AGAGAAGGGGCAAATATGAGAACAGGAATAGCCACTTCTCTTATAAAAAGCAGTAGTTTGACGGGCAATCTAGACAGAGA
CGCCGCAGTATTTGAAGTAGATGAGGCAAACTTGAGCTTTGTGGTAAATGAAATAAATCCAAATGTGGTTGTAATCACAA
ACTTCTTTAGAGACCAGTTAGACAGATTTGGTGAATTAGACCTTATTGTAAATAAGGTAAAAAAGGCTCTTTCAGACCTT
TCCAAAGATTCTTTTGTCCTTTTAAACGCAGATGACCCTTTTACTGCCTCTATAGGAGAGGACTTAGAGGCAAAAGTTCT
ATACTATGGAATTGAGGATGATATAAAAAGTCTCAAATCTTCTTCCTTTGAGCAAAAATTTTGCCCTGTATGTGGCACAA
AATACGAATACAAAAAGATATATTACGGCCACCTGGGAAACTACTACTGTCCAAACTGCGGTAAAAAACGCCCTTCTCTT
GATTTTAGAGCAAGTGATATATTTTTAAGCGAAGATGGAATAAAGTTTAAATTATCCTATAAAGATAAAATTTTTACAGT
TAAAAGCAACTTGGTAGGTTTATACAATGTTTACAACATCCTTGCTTCCACATCTGCTGGAATGCTTCTTAATTTAGATG
ATTCTACTATTTTAAAGGCAGTAGAAAATTACTGGCCTATAGAAGGACGACTACAAAAAATCCAAATAAGAGGAAAAAAA
GCTATAATAAATCTCATAAAAAACCCCGTAGGATTTGAAAGCACATTAAACATGCTCTCCCAATTTGACAAACCTCTAAA
CCTTCTTATCTTAATAAACGATAACTATGCGGATGGAAGAGATGTATCTTGGCTATGGGATGTAAATTTAGAAGAATTCT
TATCAAAAGCTAAAGTAAACCACATAATAACCTCAGGGCTAAGAGCAGAAGACATGGCTTTAAGAGTGAAATATGCTGGC
TTTGACACTGAAAGAATAAAGATAATGCCACTTAATGAAGCTGTAAAAGAAATCTTGGATATAACAAAAGAAGAGCTTAT
TGCAATTCTCCCAAATTACACTGCTTTACAAGACCTTAATAAATATCTCAAATCTCAGGGGGCATTAAAATGA

Upstream 100 bases:

>100_bases
TTAGTTTTGGGCGTTGACGATAAAGAGGAAAACGTCGTTTTACTTCAGCCAGAAAGAGAAGTAAAAGTAGGAAATAAAGT
TTATTAAAGGTGGGGAAAAA

Downstream 100 bases:

>100_bases
AGCTAACTATTGGCCACATGTATCCCGACCTTTTAAACTTATACGGTGACAGGGGAAATATAATCGCTCTAAAAAAAAGA
TGTGAATGGAGAAAAATTGA

Product: UDP-N-acetylmuramyl tripeptide synthase

Products: NA

Alternate protein names: Mur Ligase Family Protein; UDP-N-Acetylmuramyl Tripeptide Synthetase; Ligase; Mur Ligase; Mur Ligase Middle Domain Protein; UDP-N-Acetylmuramoylalanine-D-Glutamate Ligase; UDP-N-Acetylmuramate-Alanine Ligase; Conserved Domain Protein; UDP-N-Acetylmuramyl Tripeptide Synthase-Like Protein; Cell Wall Biosynthesis Protein Mur Ligase Family; Mur Ligase Middle Domain-Containing Protein; UDP-N-Acetylmuramyl Tripeptide Synthetase MurC; UDP-N-Acetylmuramyl Tripeptide Synthetase Related Protein; Peptide Ligase; Murein Ligase; UDP-N-Acetylmuramoyl-L-Alanyl-D-Glutamate-Lysine Ligase; Udp-N-Acetylmuramyl Tripeptide Synthetase; UDP-N-Acetylmuramyl Tripeptide Synthetase Like; UDP-N-Acetylmuramyl Peptide Synthetase

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKGLGVAIGKLVNISCKITGKGGTSLPGKIALMADDHLIKKLIEPLKENKVIVTGTNGKTTTSGLIAHLLSYSGRKVVHN
REGANMRTGIATSLIKSSSLTGNLDRDAAVFEVDEANLSFVVNEINPNVVVITNFFRDQLDRFGELDLIVNKVKKALSDL
SKDSFVLLNADDPFTASIGEDLEAKVLYYGIEDDIKSLKSSSFEQKFCPVCGTKYEYKKIYYGHLGNYYCPNCGKKRPSL
DFRASDIFLSEDGIKFKLSYKDKIFTVKSNLVGLYNVYNILASTSAGMLLNLDDSTILKAVENYWPIEGRLQKIQIRGKK
AIINLIKNPVGFESTLNMLSQFDKPLNLLILINDNYADGRDVSWLWDVNLEEFLSKAKVNHIITSGLRAEDMALRVKYAG
FDTERIKIMPLNEAVKEILDITKEELIAILPNYTALQDLNKYLKSQGALK

Sequences:

>Translated_450_residues
MKGLGVAIGKLVNISCKITGKGGTSLPGKIALMADDHLIKKLIEPLKENKVIVTGTNGKTTTSGLIAHLLSYSGRKVVHN
REGANMRTGIATSLIKSSSLTGNLDRDAAVFEVDEANLSFVVNEINPNVVVITNFFRDQLDRFGELDLIVNKVKKALSDL
SKDSFVLLNADDPFTASIGEDLEAKVLYYGIEDDIKSLKSSSFEQKFCPVCGTKYEYKKIYYGHLGNYYCPNCGKKRPSL
DFRASDIFLSEDGIKFKLSYKDKIFTVKSNLVGLYNVYNILASTSAGMLLNLDDSTILKAVENYWPIEGRLQKIQIRGKK
AIINLIKNPVGFESTLNMLSQFDKPLNLLILINDNYADGRDVSWLWDVNLEEFLSKAKVNHIITSGLRAEDMALRVKYAG
FDTERIKIMPLNEAVKEILDITKEELIAILPNYTALQDLNKYLKSQGALK
>Mature_450_residues
MKGLGVAIGKLVNISCKITGKGGTSLPGKIALMADDHLIKKLIEPLKENKVIVTGTNGKTTTSGLIAHLLSYSGRKVVHN
REGANMRTGIATSLIKSSSLTGNLDRDAAVFEVDEANLSFVVNEINPNVVVITNFFRDQLDRFGELDLIVNKVKKALSDL
SKDSFVLLNADDPFTASIGEDLEAKVLYYGIEDDIKSLKSSSFEQKFCPVCGTKYEYKKIYYGHLGNYYCPNCGKKRPSL
DFRASDIFLSEDGIKFKLSYKDKIFTVKSNLVGLYNVYNILASTSAGMLLNLDDSTILKAVENYWPIEGRLQKIQIRGKK
AIINLIKNPVGFESTLNMLSQFDKPLNLLILINDNYADGRDVSWLWDVNLEEFLSKAKVNHIITSGLRAEDMALRVKYAG
FDTERIKIMPLNEAVKEILDITKEELIAILPNYTALQDLNKYLKSQGALK

Specific function: Unknown

COG id: COG0769

COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50089; Mature: 50089

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS01011 FOLYLPOLYGLU_SYNT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLGVAIGKLVNISCKITGKGGTSLPGKIALMADDHLIKKLIEPLKENKVIVTGTNGKT
CCCCCEEHHEEEEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHCCEEEECCCCCC
TTSGLIAHLLSYSGRKVVHNREGANMRTGIATSLIKSSSLTGNLDRDAAVFEVDEANLSF
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEE
VVNEINPNVVVITNFFRDQLDRFGELDLIVNKVKKALSDLSKDSFVLLNADDPFTASIGE
EEEECCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
DLEAKVLYYGIEDDIKSLKSSSFEQKFCPVCGTKYEYKKIYYGHLGNYYCPNCGKKRPSL
CCEEEEEEECCHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
DFRASDIFLSEDGIKFKLSYKDKIFTVKSNLVGLYNVYNILASTSAGMLLNLDDSTILKA
CCEECEEEEECCCEEEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCHHHHHH
VENYWPIEGRLQKIQIRGKKAIINLIKNPVGFESTLNMLSQFDKPLNLLILINDNYADGR
HHHCCCCCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCC
DVSWLWDVNLEEFLSKAKVNHIITSGLRAEDMALRVKYAGFDTERIKIMPLNEAVKEILD
CCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEHHHHHHHHHH
ITKEELIAILPNYTALQDLNKYLKSQGALK
HCHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGLGVAIGKLVNISCKITGKGGTSLPGKIALMADDHLIKKLIEPLKENKVIVTGTNGKT
CCCCCEEHHEEEEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHCCEEEECCCCCC
TTSGLIAHLLSYSGRKVVHNREGANMRTGIATSLIKSSSLTGNLDRDAAVFEVDEANLSF
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEE
VVNEINPNVVVITNFFRDQLDRFGELDLIVNKVKKALSDLSKDSFVLLNADDPFTASIGE
EEEECCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
DLEAKVLYYGIEDDIKSLKSSSFEQKFCPVCGTKYEYKKIYYGHLGNYYCPNCGKKRPSL
CCEEEEEEECCHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
DFRASDIFLSEDGIKFKLSYKDKIFTVKSNLVGLYNVYNILASTSAGMLLNLDDSTILKA
CCEECEEEEECCCEEEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCHHHHHH
VENYWPIEGRLQKIQIRGKKAIINLIKNPVGFESTLNMLSQFDKPLNLLILINDNYADGR
HHHCCCCCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCC
DVSWLWDVNLEEFLSKAKVNHIITSGLRAEDMALRVKYAGFDTERIKIMPLNEAVKEILD
CCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEHHHHHHHHHH
ITKEELIAILPNYTALQDLNKYLKSQGALK
HCHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA