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The map label for this gene is RpiA [H]

Identifier: 20095101

GI number: 20095101

Start: 1667190

End: 1667828

Strand: Reverse

Name: RpiA [H]

Synonym: MK1665

Alternate gene names: 20095101

Gene position: 1667828-1667190 (Counterclockwise)

Preceding gene: 20095105

Following gene: 20095100

Centisome position: 98.4

GC content: 61.5

Gene sequence:

>639_bases
TTGAGCGGCAAACGGAACGCGGCCAGGAAAGCCGCGGAAGAGGTCTGCCGACGCGGGTACGAGGTGATCGGGGTTGGTGC
CGGCACCACCGTCGAGGCTTTCCTTGAAGAGCTGGTGAAGAGAGAGGCCGACGTACTGGTGTTCACCACGATACCCGGCA
CGATCGATGCTTGTCGCCGCATCGGACTGAACGTGACTACGATACCGCCCGAAGAGCTCCCGGTCGCCATCGACGGAGCT
GACGCCGTGGATCCCGATGGTAACCTGCTGAAAGGAGGAGGGGCCTGCCACTCGTTGGAGAAGGCGATAGATTACACCGC
CGACGAGTTCTGGGTCGTCGTGGACGAGTCGAAGCTCGTCGAGAACCTCTGGGAGCTCCCGGTACCCGTTGAGGTACTCC
GCGGCTGCTACGAGTTAACAGTTCGGACGCTGGAGGAGTTCGGTGAGGTCAGACCGAGAACGTGTGACGAGAAGTACGGG
CCCGTGGTCTCGGACTCGGGTAATCCCATCGTCGACCTGCATGTGGACGACTGGGATCCCGCCGAGCTCGAACGCGAGTT
GAACTCCGTTCCCGGCGTAGTTGAATGCGGCGTATTCCCCGGGGACAAGGTAGATAGGATCATCGTCGGGAGGTCGTAG

Upstream 100 bases:

>100_bases
TTAGGGCCCGCACCTATCACGAGGACTTTATCGGACATCGTCCGGCTACCCGCGTGTGAGGGCCCACACGCCGCATTAAG
AAACCCTCGGGGGTTCGGCT

Downstream 100 bases:

>100_bases
GGGGTGAGATGTTGCGTGTACCTCCTGTTATCGTGAATTTCAAGGCGTACTCGGAAGCGGTCGGTGAGAACGCACTACGA
CTGGCTCGAGTGGCCGCGGA

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSGKRNAARKAAEEVCRRGYEVIGVGAGTTVEAFLEELVKREADVLVFTTIPGTIDACRRIGLNVTTIPPEELPVAIDGA
DAVDPDGNLLKGGGACHSLEKAIDYTADEFWVVVDESKLVENLWELPVPVEVLRGCYELTVRTLEEFGEVRPRTCDEKYG
PVVSDSGNPIVDLHVDDWDPAELERELNSVPGVVECGVFPGDKVDRIIVGRS

Sequences:

>Translated_212_residues
MSGKRNAARKAAEEVCRRGYEVIGVGAGTTVEAFLEELVKREADVLVFTTIPGTIDACRRIGLNVTTIPPEELPVAIDGA
DAVDPDGNLLKGGGACHSLEKAIDYTADEFWVVVDESKLVENLWELPVPVEVLRGCYELTVRTLEEFGEVRPRTCDEKYG
PVVSDSGNPIVDLHVDDWDPAELERELNSVPGVVECGVFPGDKVDRIIVGRS
>Mature_211_residues
SGKRNAARKAAEEVCRRGYEVIGVGAGTTVEAFLEELVKREADVLVFTTIPGTIDACRRIGLNVTTIPPEELPVAIDGAD
AVDPDGNLLKGGGACHSLEKAIDYTADEFWVVVDESKLVENLWELPVPVEVLRGCYELTVRTLEEFGEVRPRTCDEKYGP
VVSDSGNPIVDLHVDDWDPAELERELNSVPGVVECGVFPGDKVDRIIVGRS

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=209, Percent_Identity=35.4066985645933, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1789280, Length=192, Percent_Identity=31.25, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551758, Length=216, Percent_Identity=32.4074074074074, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324669, Length=232, Percent_Identity=32.7586206896552, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364072, Length=196, Percent_Identity=33.1632653061224, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23063; Mature: 22932

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKRNAARKAAEEVCRRGYEVIGVGAGTTVEAFLEELVKREADVLVFTTIPGTIDACRR
CCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
IGLNVTTIPPEELPVAIDGADAVDPDGNLLKGGGACHSLEKAIDYTADEFWVVVDESKLV
CCCCEEECCCCCCCEEECCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCEEEEECHHHHH
ENLWELPVPVEVLRGCYELTVRTLEEFGEVRPRTCDEKYGPVVSDSGNPIVDLHVDDWDP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEECCCCCEEEEEEECCCCH
AELERELNSVPGVVECGVFPGDKVDRIIVGRS
HHHHHHHHCCCCEEEECCCCCCCCCEEEECCC
>Mature Secondary Structure 
SGKRNAARKAAEEVCRRGYEVIGVGAGTTVEAFLEELVKREADVLVFTTIPGTIDACRR
CCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
IGLNVTTIPPEELPVAIDGADAVDPDGNLLKGGGACHSLEKAIDYTADEFWVVVDESKLV
CCCCEEECCCCCCCEEECCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCEEEEECHHHHH
ENLWELPVPVEVLRGCYELTVRTLEEFGEVRPRTCDEKYGPVVSDSGNPIVDLHVDDWDP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEECCCCCEEEEEEECCCCH
AELERELNSVPGVVECGVFPGDKVDRIIVGRS
HHHHHHHHCCCCEEEECCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]