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The map label for this gene is LldP [C]

Identifier: 20095088

GI number: 20095088

Start: 1657359

End: 1658759

Strand: Reverse

Name: LldP [C]

Synonym: MK1652

Alternate gene names: 20095088

Gene position: 1658759-1657359 (Counterclockwise)

Preceding gene: 20095090

Following gene: 20095087

Centisome position: 97.86

GC content: 59.1

Gene sequence:

>1401_bases
CTGAGGTTATACAGACGTCGAGACCCTGAGCCCCAATCACCATCGTCGTCAGAAGGGGGATTACCGTTGCCATCCCTCGC
ACTGGTTGTCCCCCTGATATCAATCTCGGCTTTGATCGTAGCCGCACTTCGCGGCTGGGGGCTATTCCGCGCGTCTTCTC
TTTCCTTAGCCCTCTACCTTATAGCCTCAACATTCACTCCGTTCACCGTTCAGGTACCCTACGTTCGGGTCGTCGACTCC
GCGCTAAAAGGTGTTGAAATTTTGGCCGTCGTGTTGGCCAGCCTCACGCTCGTGGAGATGATGCGTGAAGACGGCGTGCT
GGAGGATATCGTGCACATTCTGAAGGAGACCTGCCAACTGCGCGGCCCGTGCTTGGTGGGCCTAAGCGTCGTGGCTACCG
GAGCTTTCGAGAGTGTGGCAAGCTTCGGAACGCCCGCTACTCTAGTAGGTCCACTCCTCGTCGAAGCGGGACTGAGTAAG
ACGACCGCGGCGGCCGCGGCTCTCGTGGGGCACGCTCCGTTCGGGGTGTTCGCGGCCTTCGGTGTACCGATTCTCGTCAC
TTCGGGAGTTTCAGGGATCGATCCTAAGAAGCTGAGCTTCGATGTCGCCCTCTGCATCGCTCCGAGCCTGCTGGTATTGC
CTTATGCTGTAGCGGAGACAGCCGACCTCCGGGTGTCGAAGGTCCTACTGACGACCATGGGGATTATGACCACTGCCTCC
TTGCTGGCCGTTTGGTGGGTCGCATCTCCCAGTATCGTGGGCCCGCTCTTAGTTTTGGGCGTAGCTTCCGGTTTCCTCTG
GTACCTACGAGTCGCGGGCGAGGAAGCCAGGATCAAGGTCAGCAATGACACTATCAAGGGAATGATAGTCTACGGGCTGG
TGGTCGTCGGGATAGGAGTAGTCAAGGCCCTGGACGTGAAGTGGGTGCAACCGTGGATGCTGCTGTGGGTCGCCGTATTA
TTGTACGCGACTCCCCGATGGACTCGAATGGTCGGAGCACTCATCCGTGTGCTTCGGAAGACTTGGGAGGAACTGCTTTC
GATCGTGCTCCTAATGGTCCTTGGAACGCTGATAGCTCATTCCGAACTCCCCAGCGCGATCAGGCCTTACGCGGGGTCTC
CGCTGGTCACTTTCCTGGTGGGGTTCATGGGGGAGATGGTCGTCGGCAGCACTACCGCGGTGATGGCGACTTTCGCGTCT
GGAACACCATATCCGGAGATCACACTGGCCGGTGCGGCCTGTGCGGCGGCCGCATGCCCTTACAACGTCGCCGTGGCCGC
GGCGGCCGTAAGATGCCACGAGAAGCGGGTTATGCGGAGGAGTCTCCTGGGTTCGATGTACTTGACGGTACCGACGTTAG
CGTGGTGTACCATGCTATGGATTTGGGGCGCGATGAAATGA

Upstream 100 bases:

>100_bases
ACGTTGTCTATCCGGAGGCCATAGATAGGGGCTTTGTCGTGTAAGGCGACTGCGAACTCCTTCAGGAATGCGAGATCGGA
AGTATTCCCGTTGATAGCGT

Downstream 100 bases:

>100_bases
GACGGGAGTTGATCGAAAGGCTCGAGTCACGTCTCGACCGGAGAGAGATCGAGAAAGCCCGCCGAGATTCCCACGCCCGT
CGACGTCCGAGGCCTTGTGG

Product: L-lactate permease

Products: lactate [Cytoplasm]; Proton [Cytoplasm]; glycolate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MRLYRRRDPEPQSPSSSEGGLPLPSLALVVPLISISALIVAALRGWGLFRASSLSLALYLIASTFTPFTVQVPYVRVVDS
ALKGVEILAVVLASLTLVEMMREDGVLEDIVHILKETCQLRGPCLVGLSVVATGAFESVASFGTPATLVGPLLVEAGLSK
TTAAAAALVGHAPFGVFAAFGVPILVTSGVSGIDPKKLSFDVALCIAPSLLVLPYAVAETADLRVSKVLLTTMGIMTTAS
LLAVWWVASPSIVGPLLVLGVASGFLWYLRVAGEEARIKVSNDTIKGMIVYGLVVVGIGVVKALDVKWVQPWMLLWVAVL
LYATPRWTRMVGALIRVLRKTWEELLSIVLLMVLGTLIAHSELPSAIRPYAGSPLVTFLVGFMGEMVVGSTTAVMATFAS
GTPYPEITLAGAACAAAACPYNVAVAAAAVRCHEKRVMRRSLLGSMYLTVPTLAWCTMLWIWGAMK

Sequences:

>Translated_466_residues
MRLYRRRDPEPQSPSSSEGGLPLPSLALVVPLISISALIVAALRGWGLFRASSLSLALYLIASTFTPFTVQVPYVRVVDS
ALKGVEILAVVLASLTLVEMMREDGVLEDIVHILKETCQLRGPCLVGLSVVATGAFESVASFGTPATLVGPLLVEAGLSK
TTAAAAALVGHAPFGVFAAFGVPILVTSGVSGIDPKKLSFDVALCIAPSLLVLPYAVAETADLRVSKVLLTTMGIMTTAS
LLAVWWVASPSIVGPLLVLGVASGFLWYLRVAGEEARIKVSNDTIKGMIVYGLVVVGIGVVKALDVKWVQPWMLLWVAVL
LYATPRWTRMVGALIRVLRKTWEELLSIVLLMVLGTLIAHSELPSAIRPYAGSPLVTFLVGFMGEMVVGSTTAVMATFAS
GTPYPEITLAGAACAAAACPYNVAVAAAAVRCHEKRVMRRSLLGSMYLTVPTLAWCTMLWIWGAMK
>Mature_466_residues
MRLYRRRDPEPQSPSSSEGGLPLPSLALVVPLISISALIVAALRGWGLFRASSLSLALYLIASTFTPFTVQVPYVRVVDS
ALKGVEILAVVLASLTLVEMMREDGVLEDIVHILKETCQLRGPCLVGLSVVATGAFESVASFGTPATLVGPLLVEAGLSK
TTAAAAALVGHAPFGVFAAFGVPILVTSGVSGIDPKKLSFDVALCIAPSLLVLPYAVAETADLRVSKVLLTTMGIMTTAS
LLAVWWVASPSIVGPLLVLGVASGFLWYLRVAGEEARIKVSNDTIKGMIVYGLVVVGIGVVKALDVKWVQPWMLLWVAVL
LYATPRWTRMVGALIRVLRKTWEELLSIVLLMVLGTLIAHSELPSAIRPYAGSPLVTFLVGFMGEMVVGSTTAVMATFAS
GTPYPEITLAGAACAAAACPYNVAVAAAAVRCHEKRVMRRSLLGSMYLTVPTLAWCTMLWIWGAMK

Specific function: May Play A Role In L-Lactate Transport. [C]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49376; Mature: 49376

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYRRRDPEPQSPSSSEGGLPLPSLALVVPLISISALIVAALRGWGLFRASSLSLALYL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IASTFTPFTVQVPYVRVVDSALKGVEILAVVLASLTLVEMMREDGVLEDIVHILKETCQL
HHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
RGPCLVGLSVVATGAFESVASFGTPATLVGPLLVEAGLSKTTAAAAALVGHAPFGVFAAF
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
GVPILVTSGVSGIDPKKLSFDVALCIAPSLLVLPYAVAETADLRVSKVLLTTMGIMTTAS
CCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAVWWVASPSIVGPLLVLGVASGFLWYLRVAGEEARIKVSNDTIKGMIVYGLVVVGIGV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
VKALDVKWVQPWMLLWVAVLLYATPRWTRMVGALIRVLRKTWEELLSIVLLMVLGTLIAH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SELPSAIRPYAGSPLVTFLVGFMGEMVVGSTTAVMATFASGTPYPEITLAGAACAAAACP
HCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEECHHHHHHHCCC
YNVAVAAAAVRCHEKRVMRRSLLGSMYLTVPTLAWCTMLWIWGAMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLYRRRDPEPQSPSSSEGGLPLPSLALVVPLISISALIVAALRGWGLFRASSLSLALYL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IASTFTPFTVQVPYVRVVDSALKGVEILAVVLASLTLVEMMREDGVLEDIVHILKETCQL
HHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
RGPCLVGLSVVATGAFESVASFGTPATLVGPLLVEAGLSKTTAAAAALVGHAPFGVFAAF
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
GVPILVTSGVSGIDPKKLSFDVALCIAPSLLVLPYAVAETADLRVSKVLLTTMGIMTTAS
CCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAVWWVASPSIVGPLLVLGVASGFLWYLRVAGEEARIKVSNDTIKGMIVYGLVVVGIGV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
VKALDVKWVQPWMLLWVAVLLYATPRWTRMVGALIRVLRKTWEELLSIVLLMVLGTLIAH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SELPSAIRPYAGSPLVTFLVGFMGEMVVGSTTAVMATFASGTPYPEITLAGAACAAAACP
HCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEECHHHHHHHCCC
YNVAVAAAAVRCHEKRVMRRSLLGSMYLTVPTLAWCTMLWIWGAMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: lactate [Periplasm]; Proton [Periplasm]; glycolate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] Proton [Periplasm] + glycolate [Periplasm] = Proton [Cytoplasm] + glycolate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA