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The map label for this gene is yfnA [H]

Identifier: 20095012

GI number: 20095012

Start: 1589278

End: 1590753

Strand: Reverse

Name: yfnA [H]

Synonym: MK1576

Alternate gene names: 20095012

Gene position: 1590753-1589278 (Counterclockwise)

Preceding gene: 20095013

Following gene: 20095011

Centisome position: 93.85

GC content: 58.94

Gene sequence:

>1476_bases
ATGGAGAAGGTAGGTCTCAGGCGAGAGCTCACCATGTTGGGTTTCATTTCAACGATTTGTTGTACCGTGATCGGAGGAGG
AGTCAACGTCCTGACGTGTATGATCCAAGTCAAGGCACCGGGAGTCGGTCCTTACGTTCCGTTGGCGTTCTTGATCGGGG
CCGTTCCGAGCTTGGTAGCCGGTATCGTAGCAGGAGCCCTCAGCGCGGCGGTTCCACGAGCAGGCGGTCACTACACGTAC
GTGAGCCGACTGTTCGACCCGTTCTTGGCATTCTTCAGCTCTTGGAGCCGATTCGTGGGCGAGATCGGAGCCTTCGTAGC
GATCGCGATCGGAGACGTGGCACTGTTGGCGGCGATGTGCAAGTTCTGGGGTGCACCGGCGGCAGGGAAGTGGTTGAACG
CACACACACTCGAGGTGGCGACCCTTATCATCATCTTCACGTGGCTAGTCAACGTCTTAGGAATCCGGATTTACGAGGCC
GTCGTCGATGTGATGTTCTTCATCCTGCTGACGGGTTTCTTCATCGTAGTCGGGTACGGATTCGCACACTCTCCGGCCGA
GTACCTCAAGGCGATCGGCGGAACGACCGCGCTGAAATCGCTGATATCTCAGGCTGGAGGACTACCGAAGGACGTAGGTA
CCCTCAGCGCGATATTCTCGGCGGCCGCGACGCTGGTGTTCGCGTACGTGGGCTTCGAGACGGGCACGCAGGCGGCAGGT
GAAGTCAAGAAGCCGGAGAAAACCGTGTTCAGAGGCATGTTGATCGCGCTGGGGATCATCACGGCGTACTACCTGCTGTA
CTCGGCCGCGGTGTACCACGCCGTGCCTTGGGAGTACATCTACGCTAAGGCGGCGCTCGCCGACAAGGCGGGTAGCAACT
TCACCGTCCCCGAGGCGATGGCTCCGATAATGCCGAGCGCACTCGCGGGATACGTAGCGTTCGTGGCCGCTATCGCGCTG
TTAAGCGACCTGCCGCCGATGTTCCTGTCGACCAGCAGGATGACGTTCGCCTGGGCCTACGACGGGATGTTCCCGAAGGT
GTTCGCTAAGGTGCACAAGAGCTTCGGTACTCCGCACTGGGCACTGACGGTCCTGATGGTAGTCTCGGTGATCCTGACGT
GGGCGGTCGGTAAGTTCCTGGCGGCCGTGGACATCACGACGGTAGCGCTGCTGTTCACGTACCTGTTCATCTGTATGACC
GGACTTGTCTGGAAGTTCGTAAGACCGGACATTTACGAGAAGGCCCCGTTGGGTGACAAGACCAAGAAGGCAGTCAACTG
GCTGGGAGCCACCGGTACCGTGCTGAGCCTATTCTTCCTGGGTGAGATCGCCATCAGCGACCCGACGAGCTTCTACTGGT
GGATCGCACTGATGGTACCGGGACCGTTCATCTTCTACTACGCGTACAACAGAACCGTGAAGAAGCTGGGCCCGGAGAAG
GCCAGGGAGCGTCTAATGACTATACCTCCGGAGTAA

Upstream 100 bases:

>100_bases
GAAAGGTTATAATTCCTATCCGCCGGCCTTTGCGGGATAGGTAAGATAAAACCGGAAAGCGATTTCCGGGCGGTGGTCGG
AAGTGGCTGGGGACGCTAAA

Downstream 100 bases:

>100_bases
GGGGGCTTCTCCCCCCATACGCACCGTCATCGGAACCCTCGCCGACGCACTCACCGACATGGAAGAGCGGGGCCACTCGC
TCAAAGCCGCCCTCCGTAAC

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MEKVGLRRELTMLGFISTICCTVIGGGVNVLTCMIQVKAPGVGPYVPLAFLIGAVPSLVAGIVAGALSAAVPRAGGHYTY
VSRLFDPFLAFFSSWSRFVGEIGAFVAIAIGDVALLAAMCKFWGAPAAGKWLNAHTLEVATLIIIFTWLVNVLGIRIYEA
VVDVMFFILLTGFFIVVGYGFAHSPAEYLKAIGGTTALKSLISQAGGLPKDVGTLSAIFSAAATLVFAYVGFETGTQAAG
EVKKPEKTVFRGMLIALGIITAYYLLYSAAVYHAVPWEYIYAKAALADKAGSNFTVPEAMAPIMPSALAGYVAFVAAIAL
LSDLPPMFLSTSRMTFAWAYDGMFPKVFAKVHKSFGTPHWALTVLMVVSVILTWAVGKFLAAVDITTVALLFTYLFICMT
GLVWKFVRPDIYEKAPLGDKTKKAVNWLGATGTVLSLFFLGEIAISDPTSFYWWIALMVPGPFIFYYAYNRTVKKLGPEK
ARERLMTIPPE

Sequences:

>Translated_491_residues
MEKVGLRRELTMLGFISTICCTVIGGGVNVLTCMIQVKAPGVGPYVPLAFLIGAVPSLVAGIVAGALSAAVPRAGGHYTY
VSRLFDPFLAFFSSWSRFVGEIGAFVAIAIGDVALLAAMCKFWGAPAAGKWLNAHTLEVATLIIIFTWLVNVLGIRIYEA
VVDVMFFILLTGFFIVVGYGFAHSPAEYLKAIGGTTALKSLISQAGGLPKDVGTLSAIFSAAATLVFAYVGFETGTQAAG
EVKKPEKTVFRGMLIALGIITAYYLLYSAAVYHAVPWEYIYAKAALADKAGSNFTVPEAMAPIMPSALAGYVAFVAAIAL
LSDLPPMFLSTSRMTFAWAYDGMFPKVFAKVHKSFGTPHWALTVLMVVSVILTWAVGKFLAAVDITTVALLFTYLFICMT
GLVWKFVRPDIYEKAPLGDKTKKAVNWLGATGTVLSLFFLGEIAISDPTSFYWWIALMVPGPFIFYYAYNRTVKKLGPEK
ARERLMTIPPE
>Mature_491_residues
MEKVGLRRELTMLGFISTICCTVIGGGVNVLTCMIQVKAPGVGPYVPLAFLIGAVPSLVAGIVAGALSAAVPRAGGHYTY
VSRLFDPFLAFFSSWSRFVGEIGAFVAIAIGDVALLAAMCKFWGAPAAGKWLNAHTLEVATLIIIFTWLVNVLGIRIYEA
VVDVMFFILLTGFFIVVGYGFAHSPAEYLKAIGGTTALKSLISQAGGLPKDVGTLSAIFSAAATLVFAYVGFETGTQAAG
EVKKPEKTVFRGMLIALGIITAYYLLYSAAVYHAVPWEYIYAKAALADKAGSNFTVPEAMAPIMPSALAGYVAFVAAIAL
LSDLPPMFLSTSRMTFAWAYDGMFPKVFAKVHKSFGTPHWALTVLMVVSVILTWAVGKFLAAVDITTVALLFTYLFICMT
GLVWKFVRPDIYEKAPLGDKTKKAVNWLGATGTVLSLFFLGEIAISDPTSFYWWIALMVPGPFIFYYAYNRTVKKLGPEK
ARERLMTIPPE

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=465, Percent_Identity=24.5161290322581, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87082250, Length=421, Percent_Identity=25.41567695962, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790653, Length=351, Percent_Identity=23.3618233618234, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI2367353, Length=341, Percent_Identity=25.2199413489736, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=212, Percent_Identity=25.9433962264151, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=378, Percent_Identity=23.5449735449735, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=22.9857819905213, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=22.9857819905213, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667468, Length=403, Percent_Identity=21.5880893300248, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52945; Mature: 52945

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCC
>Mature Secondary Structure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HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]