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The map label for this gene is rsmB [H]

Identifier: 20095011

GI number: 20095011

Start: 1587924

End: 1589219

Strand: Reverse

Name: rsmB [H]

Synonym: MK1575

Alternate gene names: 20095011

Gene position: 1589219-1587924 (Counterclockwise)

Preceding gene: 20095012

Following gene: 20095007

Centisome position: 93.76

GC content: 62.42

Gene sequence:

>1296_bases
ATGGAAGAGCGGGGCCACTCGCTCAAAGCCGCCCTCCGTAACGCCCTTCGCGGCATAGGCGGGCGTAGGCATAGATTCGT
TCAAGCATTAGCCCACGAGCTCGTGCGAGTTCTGGGTAATGTGGACCTAGTTCTCAACAGAGTACTCCGGGGTTCCACGG
TCGAGGACCTTCACCCGTACCTCCGCAACGCCCTACGAGTAGGCACGTGGGAGATCCACTGGCGCCGTGAGCATCCGGGG
CCCGTCACTAAGGCCGTAGTGGACGTCGTCAAGGAGCGTGTCGGACCCAAGCACGCCCGTTTCGCCAACGCCATCCTCAG
ACAGGTGGAGCGTGTGAACCCCGAGGAAGTCATCAGTTCCATTAGGGACCCTACGGCCCGCTTCGCGGCCCGCTATAACT
TCCCCAAGTGGTACGTGGAGCTCGTGCGCTCGGCCTTCGACAGCATGGACGAGTTGCGCAAGTTCCTGGAAGCCTGCAAC
CGGAGACCTGCCCGGTACGTTCGTGTCAATACCTTAGTGTCCGACCCTGAAGAAGTCGTGAGACGGTTGAAGCGAAGGGG
GATCGAAGCAGAACGGGACCCGGACGTCCCCGATGTCCTCCGCATAAGATCCGCCGAGACACCGGTCATCAAGACCCCGG
AGTTCAAGAAGGGTGAAGTGTACCCTCAGACGAAGGCCTCCGCAGCCGTCGCCCACGCCGCCGAGCCTGAGCCGGGGATG
ACCGTCGTCGACTTGTGTGCAGCTCCGGGTGGGAAAACCACCCATCTAGCCCAGCTGATGGAAGGCCGTGGGGAGATCAT
CGCAATCGACATGCACCCGAAGAGGTTCGGAACACTGAAGAAGCGGGTCAGGCAGTTCCACGCGGACGACATCGTGGAAA
CACTGTGCATGGACGCACGCGACGCGCCCGATCAGCTGGGTGAGGGGATTGCGGACTTAGTCCTCGTCGACCCGCCGTGC
ACGGGTACGGGGTCCGTCTATTCCAAGCCCGAGAAGAGGTGGGATCGGGAGACAACCGGCGAGCCGACCAAGTGGGCCCA
GCTCCAGTGGGAGCTCCTGAAGGTCGCCGTGAGGCTGCTGAAGCCGGGCGGCAGGATAGTGTACTCCACGTGTTCGATCA
CGCTCACCGAGAACGAGCGCCTGATCGAACGTCTCGTCCGGCGCTACCGGGGTCTCGAGCTCGTGGATGTTCCTCTGGAA
TGGGCTTCACCCGGTGTAAGGATGCCGGAGGCCCGCAGGATCTGGCCACATCGCCACGATACCGACGGTTTCTTCGTGGC
CCGAGTCGAGGCGTGA

Upstream 100 bases:

>100_bases
GAGAAGGCCAGGGAGCGTCTAATGACTATACCTCCGGAGTAAGGGGGCTTCTCCCCCCATACGCACCGTCATCGGAACCC
TCGCCGACGCACTCACCGAC

Downstream 100 bases:

>100_bases
TGAGGCCCGTCGCTGGTGACATTCGGATGATCGAAGGCCCCCTACCGCGGCGGCTGAACCTGCCGATGAGGATACGCCCC
CACAGGGCGACCGATGACCG

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MEERGHSLKAALRNALRGIGGRRHRFVQALAHELVRVLGNVDLVLNRVLRGSTVEDLHPYLRNALRVGTWEIHWRREHPG
PVTKAVVDVVKERVGPKHARFANAILRQVERVNPEEVISSIRDPTARFAARYNFPKWYVELVRSAFDSMDELRKFLEACN
RRPARYVRVNTLVSDPEEVVRRLKRRGIEAERDPDVPDVLRIRSAETPVIKTPEFKKGEVYPQTKASAAVAHAAEPEPGM
TVVDLCAAPGGKTTHLAQLMEGRGEIIAIDMHPKRFGTLKKRVRQFHADDIVETLCMDARDAPDQLGEGIADLVLVDPPC
TGTGSVYSKPEKRWDRETTGEPTKWAQLQWELLKVAVRLLKPGGRIVYSTCSITLTENERLIERLVRRYRGLELVDVPLE
WASPGVRMPEARRIWPHRHDTDGFFVARVEA

Sequences:

>Translated_431_residues
MEERGHSLKAALRNALRGIGGRRHRFVQALAHELVRVLGNVDLVLNRVLRGSTVEDLHPYLRNALRVGTWEIHWRREHPG
PVTKAVVDVVKERVGPKHARFANAILRQVERVNPEEVISSIRDPTARFAARYNFPKWYVELVRSAFDSMDELRKFLEACN
RRPARYVRVNTLVSDPEEVVRRLKRRGIEAERDPDVPDVLRIRSAETPVIKTPEFKKGEVYPQTKASAAVAHAAEPEPGM
TVVDLCAAPGGKTTHLAQLMEGRGEIIAIDMHPKRFGTLKKRVRQFHADDIVETLCMDARDAPDQLGEGIADLVLVDPPC
TGTGSVYSKPEKRWDRETTGEPTKWAQLQWELLKVAVRLLKPGGRIVYSTCSITLTENERLIERLVRRYRGLELVDVPLE
WASPGVRMPEARRIWPHRHDTDGFFVARVEA
>Mature_431_residues
MEERGHSLKAALRNALRGIGGRRHRFVQALAHELVRVLGNVDLVLNRVLRGSTVEDLHPYLRNALRVGTWEIHWRREHPG
PVTKAVVDVVKERVGPKHARFANAILRQVERVNPEEVISSIRDPTARFAARYNFPKWYVELVRSAFDSMDELRKFLEACN
RRPARYVRVNTLVSDPEEVVRRLKRRGIEAERDPDVPDVLRIRSAETPVIKTPEFKKGEVYPQTKASAAVAHAAEPEPGM
TVVDLCAAPGGKTTHLAQLMEGRGEIIAIDMHPKRFGTLKKRVRQFHADDIVETLCMDARDAPDQLGEGIADLVLVDPPC
TGTGSVYSKPEKRWDRETTGEPTKWAQLQWELLKVAVRLLKPGGRIVYSTCSITLTENERLIERLVRRYRGLELVDVPLE
WASPGVRMPEARRIWPHRHDTDGFFVARVEA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=322, Percent_Identity=31.055900621118, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI76150623, Length=322, Percent_Identity=31.055900621118, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI32698918, Length=215, Percent_Identity=36.7441860465116, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI8922322, Length=301, Percent_Identity=29.2358803986711, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI270288818, Length=301, Percent_Identity=29.2358803986711, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI270288816, Length=301, Percent_Identity=29.2358803986711, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI23199998, Length=301, Percent_Identity=29.2358803986711, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI40316918, Length=181, Percent_Identity=34.8066298342541, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI39995082, Length=253, Percent_Identity=28.8537549407115, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI301336155, Length=253, Percent_Identity=28.8537549407115, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI11545785, Length=232, Percent_Identity=27.1551724137931, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI2367212, Length=427, Percent_Identity=25.9953161592506, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081985, Length=308, Percent_Identity=29.8701298701299, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=319, Percent_Identity=28.5266457680251, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71998419, Length=225, Percent_Identity=36.4444444444444, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI115534021, Length=225, Percent_Identity=36.4444444444444, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25143471, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=298, Percent_Identity=30.5369127516779, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319447, Length=267, Percent_Identity=24.3445692883895, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324306, Length=270, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668781, Length=231, Percent_Identity=31.6017316017316, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356513, Length=231, Percent_Identity=31.6017316017316, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI22024126, Length=316, Percent_Identity=28.7974683544304, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21356579, Length=333, Percent_Identity=27.027027027027, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355201, Length=258, Percent_Identity=25.1937984496124, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920494, Length=157, Percent_Identity=28.6624203821656, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49014; Mature: 49014

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERGHSLKAALRNALRGIGGRRHRFVQALAHELVRVLGNVDLVLNRVLRGSTVEDLHPY
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
LRNALRVGTWEIHWRREHPGPVTKAVVDVVKERVGPKHARFANAILRQVERVNPEEVISS
HHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
IRDPTARFAARYNFPKWYVELVRSAFDSMDELRKFLEACNRRPARYVRVNTLVSDPEEVV
HCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHH
RRLKRRGIEAERDPDVPDVLRIRSAETPVIKTPEFKKGEVYPQTKASAAVAHAAEPEPGM
HHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
TVVDLCAAPGGKTTHLAQLMEGRGEIIAIDMHPKRFGTLKKRVRQFHADDIVETLCMDAR
HHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAPDQLGEGIADLVLVDPPCTGTGSVYSKPEKRWDRETTGEPTKWAQLQWELLKVAVRLL
CCHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
KPGGRIVYSTCSITLTENERLIERLVRRYRGLELVDVPLEWASPGVRMPEARRIWPHRHD
CCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCCHHCCCCCCCC
TDGFFVARVEA
CCCEEEEEECC
>Mature Secondary Structure
MEERGHSLKAALRNALRGIGGRRHRFVQALAHELVRVLGNVDLVLNRVLRGSTVEDLHPY
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
LRNALRVGTWEIHWRREHPGPVTKAVVDVVKERVGPKHARFANAILRQVERVNPEEVISS
HHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
IRDPTARFAARYNFPKWYVELVRSAFDSMDELRKFLEACNRRPARYVRVNTLVSDPEEVV
HCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHH
RRLKRRGIEAERDPDVPDVLRIRSAETPVIKTPEFKKGEVYPQTKASAAVAHAAEPEPGM
HHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
TVVDLCAAPGGKTTHLAQLMEGRGEIIAIDMHPKRFGTLKKRVRQFHADDIVETLCMDAR
HHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAPDQLGEGIADLVLVDPPCTGTGSVYSKPEKRWDRETTGEPTKWAQLQWELLKVAVRLL
CCHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
KPGGRIVYSTCSITLTENERLIERLVRRYRGLELVDVPLEWASPGVRMPEARRIWPHRHD
CCCCEEEEEEEEEEECCCHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCCHHCCCCCCCC
TDGFFVARVEA
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]